Article (Scientific journals)
Coagulopathies, risque thrombotique et anticoagulation dans la COVID-19.
Peters, Pierre; SPRYNGER, Muriel; Lancellotti, Patrizio et al.
2020In Revue Médicale de Liège, 75 (S1), p. 86-93
Peer reviewed


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Keywords :
Anticoagulants/adverse effects; Betacoronavirus; COVID-19; Coronavirus Infections; Humans; Pandemics; Pneumonia, Viral; SARS-CoV-2; Thrombosis; Coagulation; D-dimers; Disseminated intravascular coagulation; Venous thromboembolism; Thrombo-inflammation
Abstract :
[en] Clinical observations indicate that COVID-19 often provokes coagulopathies, which have been associated with high morbidity and mortality rates. These coagulopathies likely result from Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection-elicited systemic inflammation and endothelial damage. Patients with severe COVID-19 are at high risk of venous and arterial thromboembolic diseases; they can also develop disseminated intravascular coagulation in the most advanced stages of the disease. Medical Organisations on Thrombosis and Hemostasis, among which the Belgian Society on Thrombosis and Haemostasis (BSTH), have formulated recommendations for the prophylaxis and treatment of COVID-19-related venous thromboembolism in ambulatory and hospitalised patients, as well as for the anticoagulation of COVID-19 patients in need of long-term anticoagulation for unrelated cause.These recommendations provide every hospital and primary care physicians with an easy-to-use clinical guidance; they mainly rely on limited level of evidence and are likely to evolve with knowledge of COVID-19 pathophysiology and availability of data from ongoing clinical trials.
Disciplines :
Cardiovascular & respiratory systems
Author, co-author :
Peters, Pierre ;  Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
SPRYNGER, Muriel ;  Centre Hospitalier Universitaire de Liège - CHU > Département de médecine interne > Angéiologie
Lancellotti, Patrizio  ;  Université de Liège - ULiège > Département des sciences cliniques > Cardiologie - Pathologie spéciale et réhabilitation
Oury, Cécile  ;  Université de Liège - ULiège > Cardiovascular Sciences-Cardiology
Language :
Title :
Coagulopathies, risque thrombotique et anticoagulation dans la COVID-19.
Alternative titles :
[en] Coagulopathies, thrombotic risk and anticoagulation in COVID-19
Publication date :
Journal title :
Revue Médicale de Liège
Publisher :
Université de Liège. Revue Médicale de Liège, Liège, Belgium
Volume :
Issue :
Pages :
Peer reviewed :
Peer reviewed
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