Article (Scientific journals)
Role of cardiovascular imaging in cancer patients receiving cardiotoxic therapies: a position statement on behalf of the Heart Failure Association (HFA), the European Association of Cardiovascular Imaging (EACVI) and the Cardio-Oncology Council of the European Society of Cardiology (ESC)
Čelutkienė, J.; Pudil, R.; López-Fernández, T. et al.
2020In European Journal of Heart Failure, 22 (9), p. 1504-1524
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Keywords :
Cardiac magnetic resonance; Cardio-oncology; Cardiotoxicity; Computed tomography; Echocardiography; Global longitudinal strain; Heart failure; Imaging; Nuclear imaging
Abstract :
[en] Cardiovascular (CV) imaging is an important tool in baseline risk assessment and detection of CV disease in oncology patients receiving cardiotoxic cancer therapies. This position statement examines the role of echocardiography, cardiac magnetic resonance, nuclear cardiac imaging and computed tomography in the management of cancer patients. The Imaging and Cardio-Oncology Study Groups of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) in collaboration with the European Association of Cardiovascular Imaging (EACVI) and the Cardio-Oncology Council of the ESC have evaluated the current evidence for the value of modern CV imaging in the cardio-oncology field. The most relevant echocardiographic parameters, including global longitudinal strain and three-dimensional ejection fraction, are proposed. The protocol for baseline pre-treatment evaluation and specific surveillance algorithms or pathways for anthracycline chemotherapy, HER2-targeted therapies such as trastuzumab, vascular endothelial growth factor tyrosine kinase inhibitors, BCr-Abl tyrosine kinase inhibitors, proteasome inhibitors and immune checkpoint inhibitors are presented. The indications for CV imaging after completion of oncology treatment are considered. The typical consequences of radiation therapy and the possibility of their identification in the long term are also summarized. Special populations are discussed including female survivors planning pregnancy, patients with carcinoid disease, patients with cardiac tumours and patients with right heart failure. Future directions and ongoing CV imaging research in cardio-oncology are discussed. © 2020 European Society of Cardiology
Disciplines :
Cardiovascular & respiratory systems
Author, co-author :
Čelutkienė, J.;  Clinic of Cardiac and Vascular Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania, State Research Institute Centre For Innovative Medicine, Vilnius, Lithuania
Pudil, R.;  First Department of Medicine - Cardioangiology, Charles University Prague, Medical Faculty and University Hospital Hradec Králové, Hradec Kralove, Czech Republic
López-Fernández, T.;  Cardiology Department, La Paz University Hospital, IdiPAz, Ciber CV, Madrid, Spain
Grapsa, J.;  Department of Cardiology, St Bartholomew Hospital, Barts Health Trust, London, United Kingdom
Nihoyannopoulos, P.;  Unit of Inherited Cardiovascular Diseases/Heart Center of the Young and Athletes, First Department of Cardiology, Hippokrateion General Hospital, National and Kapodistrian University of Athens, Athens, Greece, National Heart and Lung Institute Imperial College London, Hammersmith Hospital, London, United Kingdom
Bergler-Klein, J.;  Department of Cardiology, Medical University of Vienna, Vienna, Austria
Cohen-Solal, A.;  UMR-S 942, Cardiology Department, Hôpital Lariboisière, AP-HP, Université de Paris, Paris, France
Farmakis, D.;  University of Cyprus Medical School, Nicosia, Cyprus, Cardio-Oncology Clinic, Heart Failure Unit, Department of Cardiology, Athens University Hospital Attikon, National and Kapodistrian University of Athens, Athens, Greece
Tocchetti, C. G.;  Department of Translational Medical Sciences, and Interdepartmental Center for Clinical and Translational Research (CIRCET), Federico II University, Naples, Italy
von Haehling, S.;  Department of Cardiology and Pneumology, University of Göttingen Medical Centre, Göttingen, Germany
Barberis, V.;  American Medical Center, American Heart Institute, Nicosia, Cyprus
Flachskampf, F. A.;  Department of Medical Sciences, Uppsala University, Clinical Physiology and Cardiology, Akademiska Hospital, Uppsala, Sweden
Čeponienė, I.;  Department of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
Haegler-Laube, E.;  Department of Cardiology, Inselspital, University of Bern, Bern, Switzerland
Suter, T.;  Department of Cardiology, Inselspital, University of Bern, Bern, Switzerland
Lapinskas, T.;  Department of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
Prasad, S.;  Department of Cardiac Magnetic Resonance, Royal Brompton Hospital, London, United Kingdom, National Heart and Lung Institute, Imperial College, London, United Kingdom
de Boer, R. A.;  Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands
Wechalekar, K.;  Department of Nuclear Medicine, Royal Brompton Hospital, London, United Kingdom
Anker, M. S.;  Division of Cardiology and Metabolism, Department of Cardiology, Charité
Berlin Institute of Health Center for Regenerative Therapies (BCRT)
German Centre for Cardiovascular Research
Charité Campus Benjamin Franklin;  Berlin, Germany
Iakobishvili, Z.;  Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Tel Aviv-Jaffa District, Clalit Health Services, Tel Aviv, Israel
Bucciarelli-Ducci, C.;  Bristol Heart Institute, Bristol NIHR Biomedical Research Centre and Clinical Research and Imaging Centre (CRIC) Bristol, University Hospitals Bristol NHS Trust and University of Bristol, Bristol, United Kingdom
Schulz-Menger, J.;  Working Group on Cardiovascular Magnetic Resonance, Experimental and Clinical Research Center a joint cooperation between the Charité - Universitätsmedizin Berlin, Department of Internal Medicine and Cardiology and the Max-Delbrueck Center for Molecular Medicine, and HELIOS Klinikum Berlin Buch, Department of Cardiology and Nephrology, Berlin, Germany, DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany
Cosyns, B.;  Department of Cardiology, CHVZ (Centrum voor Hart en Vaatziekten), ICMI (In Vivo Cellular and Molecular Imaging) Laboratory, Universitair Ziekenhuis Brussel, Brussels, Belgium
Gaemperli, O.;  Heart Clinic Hirslanden, Hirslanden Hospital, Zurich, Switzerland
Belenkov, Y.;  I.M. Sechenov's First Moscow State Medical University of Ministry of Health (Sechenov University), Moscow, Russian Federation
Hulot, J.-S.;  Université de Paris, CIC1418, Paris Cardiovascular Research Center, INSERM, Paris, France
Galderisi, M.;  Department of Advanced Biomedical Sciences, Federico II University Hospital, Naples, Italy
Lancellotti, Patrizio  ;  Université de Liège - ULiège > Département des sciences cliniques > Cardiologie - Pathologie spéciale et réhabilitation
Bax, J.;  Department of Cardiology, Leiden University Medical Centre, Leiden, Netherlands
Marwick, T. H.;  Baker Heart and Diabetes Institute, Melbourne, Australia
Chioncel, O.;  Emergency Institute for Cardiovascular Diseases C.C. Iliescu, Bucuresti, Romania, University of Medicine Carol Davila, Bucuresti, Romania
Jaarsma, T.;  Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands
Mullens, W.;  Ziekenhuis Oost Limburg, University Hasselt, Genk, Belgium
Piepoli, M.;  Heart Failure Unit, Cardiology, Guglielmo da Saliceto Hospital, Piacenza, Italy, University of Parma, Parma, Italy
Thum, T.;  Hannover Medical School, Institute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover, Germany
Heymans, S.;  Department of Cardiology, CARIM School for Cardiovascular Diseases Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands, William Harvey Research Institute, Barts Heart Centre, Queen Mary University of London, Charterhouse Square, London, United Kingdom, Department of Cardiovascular Sciences, Centre for Molecular and Vascular Biology, KU Leuven, Leuven, Belgium
Mueller, C.;  Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland
Moura, B.;  Cardiology Department, Military Hospital, and CINTESIS, CardioCare, Faculty of Medicine, Porto University, Porto, Portugal
Ruschitzka, F.;  University Heart Center, Department of Cardiology, University Hospital Zurich, Zurich, Switzerland
Zamorano, J. L.;  Cardiology Department, University Hospital Ramón y Cajal, Madrid, Spain, University Alcala, Madrid, Spain, CIBERCV, Instituto de Salud Carlos III (ISCIII), Madrid, Spain
Rosano, G.;  Department of Medical Sciences, IRCCS San Raffaele Pisana, Rome, Italy, Cardiology Clinical Academic Group, St George's Hospitals NHS Trust University of London, London, United Kingdom
Coats, A. J. S.;  IRCCS San Raffaele Pisana, Rome, Italy
Asteggiano, R.;  Cardiologist in Practice, Turin, Italy
Seferovic, P.;  University of Belgrade Faculty of Medicine and Serbian Academy of Sciences and Arts, Belgrade, Serbia
Edvardsen, T.;  Department of Cardiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Faculty of Medicine, University of Oslo, Oslo, Norway
Lyon, A. R.;  National Heart and Lung Institute, Imperial College, London, United Kingdom, Cardio-Oncology Service, Royal Brompton Hospital, London, United Kingdom
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Title :
Role of cardiovascular imaging in cancer patients receiving cardiotoxic therapies: a position statement on behalf of the Heart Failure Association (HFA), the European Association of Cardiovascular Imaging (EACVI) and the Cardio-Oncology Council of the European Society of Cardiology (ESC)
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European Journal of Heart Failure
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John Wiley and Sons Ltd
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