Article (Scientific journals)
Surfactant use in late preterm infants: a survey among Belgian neonatologists.
Cornette, L.; Mulder, A.; DeBeer, Ann et al.
2021In European Journal of Pediatrics, 180 (3), p. 885-892
Peer Reviewed verified by ORBi
 

Files


Full Text
Cornette 2020 Eur J Ped___Surfactant use in late preterm infants a survey among Belgianneonatologits.pdf
Author preprint (524.01 kB)
Download

Open access on publisher website


All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Late preterm infant; Nationwide survey; Respiratory distress syndrome; Surfactant therapy
Abstract :
[en] Specific recommendations on surfactant administration in late preterm (LPT) infants with pulmonary disease are lacking. We performed an online-based, nationwide survey amongst all (n = 102) Belgian neonatologists to identify the use of surfactant in LPT infants suffering from several respiratory pathologies. The survey used clearly defined clinical cases and resulted in a 86% response rate. Neonatologists adhere to the 200 mg/kg initial surfactant dosing scheme. Surfactant is widely used in respiratory distress syndrome (70.1%), but there is less unanimity on its use in meconium aspiration syndrome (58.0%), transient tachypnoea of the newborn (30.6%), congenital pneumonia (27.2%) and congenital diaphragmatic hernia (8.6%). Respondents adhere to the European guideline of a timely referral to a newborn intensive care unit (non-invasive ventilation and FiO(2) > 0.30 at 12 h of age), in order to minimise the risk of deterioration.Conclusion: We demonstrate a wide variety in the use of surfactant within LPT infants. The majority of Belgian neonatologists therefore urge for an investment in multi-centre trials on surfactant administration in LPT infants, in order to create an evidence-based practice as well as to reduce the strain on health care budgets.Trial registration: https://clinicaltrials.gov What is Known: • Any late preterm (LPT) infant with respiratory distress needs a timely referral to a neonatal intensive care unit in case of non-invasive ventilation and FiO(2) > 0.30 at 12 h of life, in order to minimise the risk of acute deterioration as well as chronic lung disease. • Any modest increase in morbidity in the sizeable group of LPT infants exerts a significant strain on health care budgets. What is New: • We report the attitudes and opinions of Belgian neonatologists about the use of surfactant in LPT infants suffering from several respiratory diseases. • Our survey demonstrates a significant variability in practice between neonatologists during treatment of respiratory pathologies in LPT infants. This highlights an urgent need for univocal therapeutic lines.
Disciplines :
Pediatrics
Author, co-author :
Cornette, L.
Mulder, A.
DeBeer, Ann
Malfilâtre, G.
Rigo, Vincent  ;  Université de Liège - ULiège > Département des sciences cliniques > Néonatologie
Cools, F.
Danhaive, O.
Language :
English
Title :
Surfactant use in late preterm infants: a survey among Belgian neonatologists.
Publication date :
March 2021
Journal title :
European Journal of Pediatrics
ISSN :
0340-6199
eISSN :
1432-1076
Publisher :
Springer, Germany
Volume :
180
Issue :
3
Pages :
885-892
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 18 January 2021

Statistics


Number of views
59 (2 by ULiège)
Number of downloads
19 (2 by ULiège)

Scopus citations®
 
9
Scopus citations®
without self-citations
9
OpenCitations
 
4

Bibliography


Similar publications



Contact ORBi