Le Bail, Romain ; Université de Liège - ULiège > Stem Cells-Molecular Regulation of Neurogenesis
Bonafina, Antonela ; Université de Liège - ULiège > Stem Cells-Molecular Regulation of Neurogenesis
Espuny Camacho, Ira Mercedes ✱; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques
Nguyen, Laurent ✱; Université de Liège - ULiège > Stem Cells-Molecular Regulation of Neurogenesis
✱ These authors have contributed equally to this work.
Language :
English
Title :
Learning about cell lineage, cellular diversity and evolution of the human brain through stem cell models
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Pellegrini, L., Bonfio, C., Chadwick, J., Begum, F., Skehel, M., Lancaster, M.A., Human CNS barrier-forming organoids with cerebrospinal fluid production. Science, 2020 This paper shows the formation of choroid plexus organoids (ChP) with the formation of a selective barrier and CSF-like fluid secretion. Interestingly, the transcriptomic and proteomic signature of ChP matched the in vivo choroid plexus.
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