Atteintes rénales de la COVID-19

ERPICUM, Pauline; GROSCH, Stéphanie; BOUQUEGNEAU, Antoine; HUART, Justine; Résimont, Guillaume; BOVY, Christophe; HABRAN, Lionel; Delvenne, Philippe; KRZESINSKI, Jean-Marie; BURTEY, Stéphane; DELANAYE, Pierre; Jouret, François

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Atteintes rénales de la COVID-19

ERPICUM, Pauline; GROSCH, Stéphanie; BOUQUEGNEAU, Antoine et al.

2020 • In Revue Médicale de Liège. Supplément, 75 (supplément 1), p. 109-S114

Peer reviewed

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https://hdl.handle.net/2268/254585

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33211431

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Keywords :

SARS-CoV-2; COVID-19; Atteinte rénale; Acute Kidney Injury

Abstract :

[fr] Le virus SARS-CoV-2 provoque un syndrome de détresse respiratoire aiguë, le symptôme principal de l’infection COVID-19 (pour «COronaVIrus Disease 2019»). Cette maladie infectieuse provoque une pandémie de gravité sanitaire et socio-économique majeure depuis décembre 2019. La cible principale du SARS-CoV-2 serait l’alvéole pulmonaire. Néanmoins, ce coronavirus est capable d’affecter directement ou indirectement d’autres organes, y compris les reins. Nous résumons ici la physiopathologie présumée de l’atteinte rénale de la COVID-19. L’incidence de l’insuffisance rénale aiguë varie entre 0,5 à 22 % de tous les patients infectés par le SARS-CoV-2. La nécessité d’une épuration extra-rénale est rapportée chez 5-9 % des patients pris en charge aux soins intensifs. L’analyse histologique de biopsies rénales montre, principalement, une nécrose tubulaire aiguë de sévérité variable, ainsi qu’une congestion des capillaires glomérulaires et péri-tubulaires. Une endothélite a parfois été décrite. L’atteinte inflammatoire du glomérule reste débattue. Les conséquences à moyen/long termes de la néphropathie COVID-19 sont inconnues et mériteront un suivi étroit.
[en] The SARS-CoV-2 virus causes a respiratory distress syndrome, the main symptom of COVID-19 (for “COronaVIrus Disease 2019”). This infectious disease has been causing a major health and socio-economic pandemic since December 2019. The pulmonary alveolus is regarded as the main target of SARS-CoV-2. However, this coronavirus is capable of directly or indirectly affecting other organs, including the kidneys. Here, we summarize the presumed pathophysiology of COVID-19 renal disease. The incidence of acute kidney injury ranges from 0,5 to 22 % of all patients infected with SARS-CoV-2. The need for renal replacement therapy is reported in 5-9 % of patients in intensive care. Histological analysis of renal biopsies mainly shows acute tubular necrosis of varying severity, as well as the congestion of glomerular and peri-tubular capillaries. Endothelitis has been described in few cases. Evidence for a factual inflammation of the glomerulus remains controversial. The medium/long term consequences of COVID-19 nephropathy are unknown and will deserve a tight follow-up.

Disciplines :

Urology & nephrology
Anatomy (cytology, histology, embryology...) & physiology

Author, co-author :

ERPICUM, Pauline ; Centre Hospitalier Universitaire de Liège - CHU > Département de médecine interne > Service de néphrologie

GROSCH, Stéphanie ; Centre Hospitalier Universitaire de Liège - CHU > Département de médecine interne > Service de néphrologie

BOUQUEGNEAU, Antoine ; Centre Hospitalier Universitaire de Liège - CHU > Département de médecine interne > Service de néphrologie

HUART, Justine ; Centre Hospitalier Universitaire de Liège - CHU > Département de médecine interne > Service de néphrologie

Résimont, Guillaume ; Centre Hospitalier Universitaire de Liège - CHU > Département de médecine interne > Service de néphrologie

BOVY, Christophe ; Centre Hospitalier Universitaire de Liège - CHU > Département de médecine interne > Service de néphrologie

HABRAN, Lionel ; Centre Hospitalier Universitaire de Liège - CHU > Unilab > Anatomie et Cytologie Pathologiques

Delvenne, Philippe ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques

KRZESINSKI, Jean-Marie ; Centre Hospitalier Universitaire de Liège - CHU > Département de médecine interne > Service de néphrologie

BURTEY, Stéphane; Assistante Publique des Hôpitaux de Marseille, France > Centre de Néphrologie et Transplantation rénale

DELANAYE, Pierre ; Centre Hospitalier Universitaire de Liège - CHU > Département de médecine interne > Service de néphrologie

Jouret, François ; Université de Liège - ULiège > Cardiovascular Sc.-Lab. of Translational Res. in Nephrology

Language :

French

Title :

Atteintes rénales de la COVID-19

Alternative titles :

[en] Kidney injury in COVID-19

Publication date :

2020

Journal title :

Revue Médicale de Liège. Supplément

ISSN :

0035-3663

Publisher :

ULiège - Université de Liège, Liège, Belgium

Volume :

Issue :

supplément 1

Pages :

S109-S114

Peer reviewed :

Peer reviewed

Available on ORBi :

since 31 December 2020

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Bibliography

Davenne E, Giot JB. Coronavirus et COVID-19 : le point sur une pandémie galopante. Rev Med Liege 2020;75:218-25.
Lipsitch M, Swerdlow DL, Finelli L. Defining the epidemiology of Covid-19 - studies needed. N Engl J Med 2020;382:1194-6.
Guan W, Ni Z, Hu Y, et al. Clinical characteristics of Coronavirus Disease 2019 in China. N Engl J Med 2020;382:1708-20.
Wu C, Chen X, Cai Y, et al. Risk factors associated with acute respiratory distress syndrome and death in patients with Coronavirus Disease 2019 pneumonia in Wuhan, China. JAMA Intern Med 2020;180:934-943.
Roser M, Ritchie H. Coronavirus Disease (COVID-19). Our World in data. En ligne : https://ourworldindata.org/coronavirus. Dernière consultation le 10 mars 2020.
Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020;395:497-506.
Perico L, Benigni A, Remuzzi G. Should COVID-19 concern nephrologists? Why and to what extent? The emerging impasse of angiotensin blockade. Nephron 2020;144:213-21.
Lai AS, Lai KN. Viral nephropathy. Nat Clin Pract Nephrol 2006;2:254-62.
Guilbeau-Frugier C, Delisle MB, Modesto-Segonds A. Glomérulonéphrites au cours des infections virales (hors infections virales du foie et hors VIH). Dans : Atlas de Pathologie rénale. Paris;Flammarion;2008:568-73.
Kupin WL. Viral-associated GN : hepatitis B and other viral infections. Clin J Am Soc Nephrol 2017;12:1529-33.
Berns JS, Bloom RD. Viral nephropathies : core curriculum 2008. Am J Kidney Dis 2008;52:370-81.
Pan X, Xu D, Zhang H, et al. Identification of a potential mechanism of acute kidney injury during the COVID-19 outbreak : a study based on single-cell transcriptome analysis. Intensive Care Med 2020;46:1114-6.
Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China : a retrospective cohort study. Lancet 2020;395:1054-62.
Richardson S, Hirsch JS, Narasimhan M, et al. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area. JAMA 2020;323:2052-9.
Wang L, Li X, Chen H, et al. Coronavirus Disease 19 infection does not result in acute kidney injury : an analysis of 116 hospitalized patients from Wuhan, China. Am J Nephrol 2020;51:343-8.
Pei G, Zhang Z, Peng J, et al. Renal involvement and early prognosis in patients with COVID-19 pneumonia. J Am Soc Nephrol 2020;31:1157-65.
Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China : a descriptive study. Lancet 2020;395:507-513.
Ng JJ, Luo Y, Phua K, Choong AM. Acute kidney injury in hospitalized patients with coronavirus disease 2019 (COVID-19) : A meta-analysis. J Infect 2020;81:647-79.
Cheng Y, Luo R, Wang K, et al. Kidney disease is associated with in-hospital death of patients with COVID-19. Kidney Int 2020;97:829-38.
Naicker S, Yang C, Hwang SJ, et al. The novel Coronavirus 2019 epidemic and kidneys. Kidney Int 2020;97:824-8.
Docherty AB, Harrison EM, Green CA, et al. Features of 16, 749 hospitalised UK patients with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol. MedRxiv 2020;doi: https://doi.org/10.1101/2020.04.23.20076042.
Delanaye P, Résimont G, Bigot-Corbel E, et al. Urinary strips for proteins : easy to do but difficult to read! Ann Biol Clin 2018;76:617-26.
Résimont G, Gadisseur R, Lutteri L, et al. Comment j'explore... une protéinurie. Rev Med Liege 2018;73:519-25.
Kormann R, Jacquot A, Alla A, et al. Coronavirus disease 2019 : acute Fanconi syndrome precedes acute kidney injury. Clin Kidney J 2020;13:362.
Hong D, Long L, Wang AY, et al. Kidney manifestations of mild, moderate and severe coronavirus disease 2019 : a retrospective cohort study. Clin Kidney J 2020;13:340-6.
Werion A, Belkhir L, Perrot M, et al. SARS-CoV-2 causes a specific dysfunction of the kidney proximal tubule. Kidney Int 2020;S0085-2538:30912-1.
Santoriello D, Khairallah P, Bomback AS, et al. Postmortem kidney pathology findings in patients with COVID-19. J Am Soc Nephrol 2020;31:2158-67.
Golmai P, Larsen CP, DeVita MV, et al. Histopathologic and ultrastructural findings in postmortem kidney biopsy material in 12 patients with AKI and COVID-19. J Am Soc Nephrol 2020;31:1944-7.
Diao B, Wang C, Wang R, et al. Human kidney is a target for novel severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) Infection. MedRxiv 2020; doi:10.1101/2020.03 .04.20031120.
Bradley BT, Maioli H, Johnston R, et al. Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State : a case series. Lancet 2020;396:320-32.
Su H, Yang M, Wan C, et al. Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China. Kidney Int 2020;98:219-27.
Menter T, Haslbauer JD, Nienhold R, et al. Postmortem examination of COVID-19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings in lungs and other organs suggesting vascular dysfunction. Histopathology 2020;77:198-209.
Sharma P, Uppal NN, Wanchoo R, et al. COVID-19-associated kidney injury : a case series of kidney biopsy findings. J Am Soc Nephrol 2020;31:1948-58.
Kudose S, Batal I, Santoriello D, et al. Kidney biopsy findings in patients with COVID-19. J Am Soc Nephrol 2020;31:1959-68.
Calomeni E, Satoskar A, Ayoub I, et al. Multivesicular bodies mimicking SARS-CoV-2 in patients without COVID-19. Kidney Int 2020;98:233-4.
Miller SE, Brealey JK. Visualization of putative coronavirus in kidney. Kidney Int 2020;98:231.
Varga Z, Flammer AJ, Steiger P, et al. Endothelial cell infection and endotheliitis in COVID-19. Lancet 2020;395:1417-8.
Rapkiewicz AV, Mai X, Carsons SE, et al. Megakaryocytes and platelet-fibrin thrombi characterize multi-organ thrombosis at autopsy in COVID-19 : a case series. EClinicalMedicine 2020;24:100434.
Connors JM, Levy JH. COVID-19 and its implications for thrombosis and anticoagulation. Blood 2020;135:2033-40.
Larsen CP, Bourne TD, Wilson JD, et al. Collapsing glomerulopathy in a patient with Coronavirus Disease 2019 (COVID-19). Kidney Int Reports 2020;5:935-9.
Kissling S, Rotman S, Gerber C, et al. Collapsing glomerulopathy in a COVID-19 patient. Kidney Int 2020;98:228-39.
Gaillard F, Ismael S, Sannier A, et al. Tubuloreticular inclusions in COVID-19-related collapsing glomerulopathy. Kidney Int 2020;98:241.
Couturier A, Ferlicot S, Chevalier K, et al. Indirect effects of severe acute respiratory syndrome coronavirus 2 on the kidney in coronavirus disease patients. Clin Kidney J 2020;13:347-53.
Durvasula R, Wellington T, McNamara E, Watnick S. COVID- 19 and kidney failure in the acute care setting : our experience from Seattle. Am J Kidney Dis 2020;76:4-6.
Mehta P, McAuley DF, Brown M, et al. COVID-19 : consider cytokine storm syndromes and immunosuppression. Lancet 2020;395:1033-4.
Ronco C, Reis T. Kidney involvement in COVID-19 and rationale for extracorporeal therapies. Nat Rev Nephrol 2020;16:308-10.
Hoffmann M, Kleine-Weber H, Schroeder S, et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell 2020;181:271-80.
Ling Y, Xu SB, Lin YX, et al. Persistence and clearance of viral RNA in 2019 novel coronavirus disease rehabilitation patients. Chin Med J 2020;133:1039-43.
Pan Y, Zhang D, Yang P, et al. Viral load of SARS-CoV-2 in clinical samples. Lancet Infect Dis 2020;20:411-2.
Wang W, Xu Y, Gao R, et al. Detection of SARS-CoV-2 in different types of clinical specimens. JAMA 2020;323:1843-4.
Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA 2020;323:1061.
Yang X, Yu Y, Xu J, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China : a single-centered, retrospective, observational study. Lancet Respir Med 2020;8:475-81.
Cao B, Wang Y, Wen D, et al. A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19. N Engl J Med 2020;382:1787-99.
Chen T, Wu D, Chen H, et al. Clinical characteristics of 113 deceased patients with coronavirus disease 2019 : retrospective study. BMJ 2020;368:m1091.
Arentz M, Yim E, Klaff L, et al. Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington State. JAMA 2020;323:1612.
Zheng F, Liao C, Fan Q, et al. Clinical characteristics of children with Coronavirus Disease 2019 in Hubei, China. Curr Med Sci 2020;40:275-80.
Shi S, Qin M, Shen B, et al. Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China. JAMA Cardiol 2020;5:802-10.
Qiu H, Wu J, Hong L, et al. Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID- 19) in Zhejiang, China : an observational cohort study. Lancet Infect Dis 2020;20:689-96.
Guo T, Fan Y, Chen M, et al. Cardiovascular implications of fatal outcomes of patients with Coronavirus Disease 2019 (COVID-19). JAMA Cardiol 2020;5:1-8.
Chen G, Wu D, Guo W, et al. Clinical and immunological features of severe and moderate coronavirus disease 2019. J Clin Invest 2020;130:2620-9.
Price-Haywood EG, Burton J, Fort D, Seoane L. Hospitalization and mortality among black patients and white patients with Covid-19. N Engl J Med 2020;382:2534-43.