[en] Endocrine disruptors (EDs) are defined by the World Health Organization (WHO) as exogenous compounds or mixtures that alter function(s) of the endocrine system and consequently cause adverse effects in an intact organism, or its progeny, or (sub)populations. European regulations on pesticides, biocides, cosmetics, and industrial chemicals require the European Commission to establish scientific criteria to define EDs. Objectives: We address the scientific relevance of four options for the identification of EDs proposed by the European Commission.
Disciplines :
Endocrinology, metabolism & nutrition
Author, co-author :
Slama, R.; Team of Environmental Epidemiology, IAB (Institute of Advanced Biosciences), Inserm, CNRS, University Grenoble-Alpes, IAB joint research center, Grenoble (La Tronche), France
Bourguignon, Jean-Pierre ; Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
Demeneix, B.; Department RDDM, Muséum National d’Histoire Naturell, UMR CNRS/MNHN 7221, Paris, France
Ivell, R.; School of Biosciences, University of Nottingham, Nottingham, United Kingdom, School of Veterinary Medicine and Science, University of Nottingham, Nottingham, United Kingdom
Panzica, G.; Department of Neuroscience, University of Torino, Turin, Italy, Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano, Italy
Kortenkamp, A.; Institute of Environment, Health and Societies, Brunel University London, Uxbridge, United Kingdom
Zoeller, R. T.; Department of Biology, University of Massachusetts, Amherst, MA, United States
Language :
English
Title :
Scientific issues relevant to setting regulatory criteria to identify endocrine-disrupting substances in the european union
Publication date :
2016
Journal title :
Environmental Health Perspectives
ISSN :
0091-6765
Publisher :
Public Health Services, US Dept of Health and Human Services
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