[en] Cryptosporidiosis is currently recognized worldwide as a leading cause of moderate to severe diarrhea. In Europe, large water- and foodborne outbreaks have been reported, highlighting
the widespread distribution of the parasite and its important health impact. Surveillance networks
have been progressively set up and the aim of this study was to present recent epidemiological
data obtained in France from 2017 to 2019 by the National Reference Center—Expert Laboratory of
cryptosporidiosis (Centre National de Référence–Laboratoire Expert cryptosporidioses CNR-LE).
Data were obtained from online reports of volunteer network participants and stools were sent to the CNR-LE for species identification and GP60 genotyping. During this period, data from 750 online reports were available. Cryptosporidiosis occurred predominantly in young children (<5 years old) and in young adults, especially during late summer. Most patients were immunocompetent (60%), and deaths were reported only in immunocompromised patients. Cryptosporidium parvum was largely predominant (72% of cases) over C. hominis (24%) and some other uncommon species. C. parvum GP60 subtypes IIa and IId were the most represented, which suggests frequent zoonotic transmission.
For C. hominis, subtypes IbA10G2 and IaA22R2 were predominant.
Research center :
CNR LE cryptosporidiosis
Disciplines :
Laboratory medicine & medical technology
Author, co-author :
Costa, Damien; University Hospital of Rouen, 76000 Rouen, France ; EA ESCAPE 7510, University of Medicine Pharmacy Rouen, 76000 Rouen, France ; CNR LE Cryptosporidiosis, Santé Publique France, 76000 Rouen, France
Razakandrainibe, Romy; EA ESCAPE 7510, University of Medicine Pharmacy Rouen, 76000 Rouen, France ; CNR LE Cryptosporidiosis, Santé Publique France, 76000 Rouen, France
Valot, Stéphane; CNR LE Cryptosporidiosis Collaborating Laboratory, Santé Publique France, 21000 Dijon, France ; University Hospital of Dijon, 21000 Dijon, France
Vannier, Margot; Rouen University Hospital, 76000 Rouen, France > Biostatistics
Sautour, Marc; University Hospital of Dijon, 21000 Dijon, France > Parasitology/Mycology
Basmaciyan, Louise; CNR LE Cryptosporidiosis Collaborating Laboratory, Santé Publique France, 21000 Dijon, France ; University Hospital of Dijon, 21000 Dijon, France
Gargala, Gilles; University Hospital of Rouen, 76000 Rouen, France ; EA ESCAPE 7510, University of Medicine Pharmacy Rouen, 76000 Rouen, France ; CNR LE Cryptosporidiosis, Santé Publique France, 76000 Rouen, France
Viller, Venceslas; CNR LE Cryptosporidiosis, Santé Publique France, 76000 Rouen, France
Lemeteil, Denis; University Hospital of Rouen, 76000 Rouen, France > Parasitology/Mycology
Ballet, Jean-Jacques; EA ESCAPE 7510, University of Medicine Pharmacy Rouen, 76000 Rouen, France
French National Network on Surveillance of Human Cryptosporidiosis
Hayette, Marie-Pierre ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Bact., mycologie, parasitologie, virologie, microbio.
Dalle, frédéric; CNR LE Cryptosporidiosis Collaborating Laboratory, Santé Publique France, 21000 Dijon, France ; University Hospital of Dijon, 21000 Dijon, France
Favennec, Loïc; University Hospital of Rouen, 76000 Rouen, France ; EA ESCAPE 7510, University of Medicine Pharmacy Rouen, 76000 Rouen, France ; CNR LE Cryptosporidiosis, Santé Publique France, 76000 Rouen, France
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