Betacoronavirus; Coronavirus Infections/complications/transmission; Cytoreduction Surgical Procedures; Female; France; Genital Neoplasms, Female/complications/surgery; Gynecologic Surgical Procedures/adverse effects; Humans; Minimally Invasive Surgical Procedures; Pandemics; Pneumonia, Viral/complications/transmission; Practice Guidelines as Topic; Societies, Medical; COVID-19; Cancer gynécologique; Guideline; Gynaecological cancer; Management; Prise en charge; Recommandation
Abstract :
[en] INTRODUCTION: Recommendations for the management of patients with gynecological cancer during the COVID-19 pandemic period. MATERIAL AND METHOD: Recommendations based on the consensus conference model. RESULTS: In the case of a COVID-19 positive patient, surgical management should be postponed for at least 15 days. For cervical cancer, the place of surgery must be re-evaluated in relation to radiotherapy and Radio-Chemotherapy-Concomitant and the value of lymph node staging surgeries must be reviewed on a case-by-case basis. For advanced ovarian cancers, neo-adjuvant chemotherapy should be favored even if primary cytoreduction surgery could be envisaged. It is lawful not to offer hyperthermic intraperitoneal chemotherapy during a COVID-19 pandemic. In the case of patients who must undergo interval surgery, it is possible to continue the chemotherapy and to offer surgery after 6 cycles of chemotherapy. For early stage endometrial cancer, in case of low and intermediate preoperative ESMO risk, hysterectomy with bilateral annexectomy associated with a sentinel lymph node procedure should be favored. It is possible to consider postponing surgery for 1 to 2 months in low-risk endometrial cancers (FIGO Ia stage on MRI and grade 1-2 endometrioid cancer on endometrial biopsy). For high ESMO risk, it ispossible to favor the MSKCC algorithm (combining PET-CT and sentinel lymph node biopsy) in order to omit pelvic and lumbar-aortic lymphadenectomies. CONCLUSION: During COVID-19 pandemic, patients suffering from cancer should not lose life chance, while limiting the risks associated with the virus.
Disciplines :
Oncology
Author, co-author :
Akladios, C.
Azais, H.
Ballester, M.
Bendifallah, S.
Bolze, P.-A.
Bourdel, N.
Bricou, A.
Canlorbe, G.
Carcopino, X.
Chauvet, P.
Collinet, P.
Coutant, C.
Dabi, Y.
Dion, L.
Gauthier, T.
Graesslin, O.
Huchon, C.
Koskas, M.
Kridelka, Frédéric ; Université de Liège - ULiège > Département des sciences cliniques > Gynécologie-Obstétrique