Reference : Biochemical markers and radiographic scores as an evaluation for the osteochondral st...
Dissertations and theses : Master of advanced studies dissertation
Life sciences : Veterinary medicine & animal health
Biochemical markers and radiographic scores as an evaluation for the osteochondral status of Warmblood stallions
[fr] Marquers biologiques et score radiologique comme outil d'evaluation du status osteoarticulaire chez des etalons de sport Belge
Verwilghen, Denis mailto [Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Anesthésiologie gén. et pathologie chirurg. des grds animaux >]
University of Liege, ​Liege, ​​Belgium
DES: Diplome d'Etude Specialisé en chirurgie des grands animaux
Serteyn, Didier mailto
[en] Establishing the osteoarticular status of the horse is often performed by means of radiological screening of the animals. Widespread blood sampling could reveal to be an interesting alternative to this procedure which is time consuming and sometimes technically difficult. The aim of this study was to investigate the relationship between the radiological status of the horses and the levels of biochemical markers of cartilage degradation and synovial inflammation. A specific radiological scoring and classification system was therefore developed and applied on 63 stallions presented for studbook admission. Additionally, groups of horses were established according to the occurrence of osteochondrosis, degenerative joint disease and distal interphalangeal joint effusion. Insulin growth factor-I, myeloperoxidases, Coll2-1 and Coll2-1NO2 were used as blood markers. The combination of the blood parameters did not seem to correlate with the used scoring system. Coll2-1NO2 levels however tended to increase with poorer radiological class and this could therefore potentially be a useful predictor of the osteoarticular status in the horse. Coll2-1 levels were significantly higher in the degenerative joint disease group. A high percentage of horses with distal interphalangeal joint effusion was present in this study and was associated with decreased IGF-I and increased Coll2
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