[en] Pituitary adenomas are usually nonmalignant, but have a heavy burden on patients and health care systems. Increased availability of MRI has led to an increase in incidentally found pituitary lesions and clinically relevant pituitary adenomas. Epidemiologic studies show that pituitary adenomas are increasing in incidence (between 3.9 and 7.4 cases per 100,000 per year) and prevalence (76 to 116 cases per 100,000 population) in the general population (approximately 1 case per 1000 of the general population). Most new cases diagnosed are prolactinomas and nonsecreting pituitary adenomas. Most clinically relevant pituitary adenomas occur in females, but pituitary adenomas are clinically heterogeneous.
Disciplines :
Endocrinology, metabolism & nutrition
Author, co-author :
Daly, Adrian ; Université de Liège - ULiège > Département des sciences cliniques > Endocrinologie
Beckers, Albert ; Université de Liège - ULiège > Département des sciences cliniques > Endocrinologie
Language :
English
Title :
The Epidemiology of Pituitary Adenomas.
Publication date :
2020
Journal title :
Endocrinology and Metabolism Clinics of North America
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Bibliography
Melmed, S., Mechanisms for pituitary tumorigenesis: the plastic pituitary. J Clin Invest 112:11 (2003), 1603–1618.
Asa, S.L., Ezzat, S., The pathogenesis of pituitary tumors. Annu Rev Pathol 4 (2009), 97–126.
Vandeva, S., Daly, A.F., Petrossians, P., et al. GENETICS IN ENDOCRINOLOGY: somatic and germline mutations in the pathogenesis of pituitary adenomas. Eur J Endocrinol, 2019, 10.1530/EJE-19-0602.
Freda, P.U., Beckers, A.M., Katznelson, L., et al. Pituitary incidentaloma: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 96:4 (2011), 894–904.
Costello, R.T., Subclinical Adenoma of the Pituitary Gland. Am J Pathol 12:2 (1936), 205–216 Available at: http://www.ncbi.nlm.nih.gov/pubmed/19970261 Accessed January 20, 2020.
Ezzat, S., Asa, S.L., Couldwell, W.T., et al. The prevalence of pituitary adenomas: a systematic review. Cancer 101:3 (2004), 613–619.
Molitch, M.E., Pituitary incidentalomas. Best Pract Res Clin Endocrinol Metab 23:5 (2009), 667–675.
Buurman, H., Saeger, W., Subclinical adenomas in postmortem pituitaries: classification and correlations to clinical data. Eur J Endocrinol 154:5 (2006), 753–758.
Vasilev, V., Rostomyan, L., Daly, A.F., et al. Management of endocrine disease: pituitary “incidentaloma”: neuroradiological assessment and differential diagnosis. Eur J Endocrinol 175:4 (2016), R171–R184.
Famini, P., Maya, M.M., Melmed, S., Pituitary magnetic resonance imaging for sellar and parasellar masses: ten-year experience in 2598 patients. J Clin Endocrinol Metab 96:6 (2011), 1633–1641.
Yue, N.C., Longstreth, W.T., Elster, A.D., et al. Clinically serious abnormalities found incidentally at MR imaging of the brain: data from the Cardiovascular Health Study. Radiology 202:1 (1997), 41–46, 10.1148/radiology.202.1.8988190.
Haberg, A.K., Hammer, T.A., Kvistad, K.A., et al. Incidental intracranial findings and their clinical impact; The HUNT MRI Study in a general population of 1006 participants between 50-66 Years. PLoS One, 11(3), 2016, 10.1371/journal.pone.0151080.
Sandeman, E.M., Hernandez Mdel, C.V., Morris, Z., et al. Incidental findings on brain MR imaging in older community-dwelling subjects are common but serious medical consequences are rare: a cohort study. PLoS One, 8(8), 2013, 10.1371/journal.pone.0071467.
Karavitaki, N., Collison, K., Halliday, J., et al. What is the natural history of nonoperated nonfunctioning pituitary adenomas?. Clin Endocrinol (Oxf) 67:6 (2007), 938–943.
Hoang, J.K., Hoffman, A.R., González, R.G., et al. Management of incidental pituitary findings on CT, MRI, and 18 F-fluorodeoxyglucose PET: a white paper of the ACR Incidental Findings Committee. J Am Coll Radiol 15:7 (2018), 966–972.
Ostrom, Q.T., Cioffi, G., Gittleman, H., et al. CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2012–2016. Neuro Oncol 21:Supplement_5 (2019), v1–v100.
Fainstein Day, P., Loto, M.G., Glerean, M., et al. Incidence and prevalence of clinically relevant pituitary adenomas: retrospective cohort study in a health management organization in Buenos Aires, Argentina. Arch Endocrinol Metab 60:6 (2016), 554–561.
Gruppetta, M., Mercieca, C., Vassallo, J., Prevalence and incidence of pituitary adenomas: a population based study in Malta. Pituitary 16:4 (2013), 545–553.
Al-Dahmani, K., Mohammad, S., Imran, F., et al. Sellar masses: an epidemiological study from the department of medicine, Tawam Hospital in affiliation with. Can J Neurol Sci 43 (2016), 291–297.
Agustsson, T.T., Baldvinsdottir, T., Jonasson, J.G., et al. The epidemiology of pituitary adenomas in Iceland, 1955-2012: a nationwide population-based study. Eur J Endocrinol 173:5 (2015), 655–664.
Raappana, A., Koivukangas, J., Ebeling, T., et al. Incidence of pituitary adenomas in Northern Finland in 1992-2007. J Clin Endocrinol Metab 95:9 (2010), 4268–4275.
Tjörnstrand, A., Gunnarsson, K., Evert, M., et al. The incidence rate of pituitary adenomas in western Sweden for the period 2001-2011. Eur J Endocrinol 171:4 (2014), 519–526.
Ahmad, O.B., Boschi-Pinto, C., Lopez Christopher, A.D., et al. Age standardization of rates: a new WHO standard. 2001 World Health Organization Discussion Paper Series 31. Available at: https://www.who.int/healthinfo/paper31.pdf.
Naves, L.A., Porto, L.B., Rosa, J.W.C., et al. Geographical information system (GIS) as a new tool to evaluate epidemiology based on spatial analysis and clinical outcomes in acromegaly. Pituitary 18:1 (2015), 8–15.
Zakir, J.C., Casulari, L.A., Rosa, J.W.C., et al. Prognostic value of invasion, markers of proliferation, and classification of giant pituitary tumors, in a georeferred cohort in Brazil of 50 patients, with a long-term postoperative follow-up. Int J Endocrinol, 2016, 2016, 7964523.
Daly, A.F., Rixhon, M., Adam, C., et al. High prevalence of pituitary adenomas: a cross-sectional study in the province of Liège, Belgium. J Clin Endocrinol Metab 91:12 (2006), 4769–4775.
Fernandez, A., Karavitaki, N., Wass, J.A., Prevalence of pituitary adenomas: a community-based, cross-sectional study in Banbury (Oxfordshire, UK). Clin Endocrinol 72:3 (2010), 377–382.
Fontana Gaillard, R.E., Epidemiology of pituitary adenoma: results of the first Swiss study. Rev Med Suisse 5:223 (2009), 2172–2174.
Vroonen, L., Daly, A.F., Beckers, A., Epidemiology and management challenges in prolactinomas. Neuroendocrinology 109:1 (2019), 20–27.
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