[en] Since January 2020, the Novel Coronavirus Disease 2019 (COVID-19) pandemic has dramatically impacted the world. In March 2020, the COVID-19 epidemic reached Belgium creating uncertainty towards all aspects of life. There has been an impressive capacity and solidarity of all healthcare professionals to acutely reconvert facilities to treat these patients. In the context of liver transplantation (LTx), concerns are raised about organ donation shortage and safety, the ethics of using limited healthcare resources for LTx, selection criteria for LTx during the epidemic and the risk of de novo COVID-19 infection on the waiting list and after LTx. BeLIAC makes several recommendations to try to mitigate the deleterious effect that this epidemic has/will have on donation and LTx, taking into account the available resources, and trying to maximize patients and healthcare professionals' safety.
Delwaide, Jean ; Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
Detry, Olivier ; Université de Liège - ULiège > Département des sciences cliniques > Pathologie chirurgicale abdominale et endocrinienne
DELBOUILLE, Marie-Hélène ; Centre Hospitalier Universitaire de Liège - CHU > Département de chirurgie > Chirurgie abdo, sénologique, endocrine et de transplantation
SCIENSANO, 2020, Epidemiology monitoring of the COVID-19 epidemic in Belgium, viewed 28 April 2020, .
FRANCQUE S., LANTHIER N., VERBEKE L., REYNAERT H., VAN STEENKISTE C., VONGHIA L. et al. The Belgian Association for Study of the Liver Guidance Document on the Management of Adult and Paediatric Non-Alcoholic Fatty Liver Disease. Acta Gastroentero. Belg., 2018, 81: 55-81.
EASL Clinical Practice Guidelines: Liver transplantation. J. Hepatol., 2016, 64: 433-485.
SCHIELKE A., MEURISSE N., LAMPROYE A., HONORÉ P., DELWAIDE J., HUSTINX R. et al. Selection criteria for liver transplantation in patients with hepatocellular carcinoma. Eastern and western experiences, and pe-spectives for the future. Acta Gastroentero. Belg., 2019, 82: 314-318.
LAURENT S., VERHELST X., GEERTS A., GEBOES K., DE MAN M., TROISI R. et al. Update on liver transplantation for cholangiocarcinoma: a review of the recent literature. Acta Gastroentero. Belg., 2019, 82: 417-420.
ANGELICO R., TRAPANI S., MANZIA T. M., LOMBARDINI L., TISONE G., CARDILLO M. The COVID-19 outbreak in Italy: Initial implications for organ transplantation programs. Am. J. Transplant., 2020.
FERNÁNDEZ-RUIZ M., ANDRÉS A., LOINAZ C., DELGADO J. F., LÓPEZ-MEDRANO F., SAN JUAN R. et al. COVID-19 in solid organ transplant recipients: a single-center case series from Spain. Am. J. Transplant., 2020.
BOETTLER T., NEWSOME P. N., MONDELLI M. U., MATICIC M., CORDERO E., CORNBERG M. et al. Care of patients with liver disease during the COVID-19 pandemic: EASL-ESCMID position paper. JHEP Rep., 2020, 2: 100113-100113.
MORIS D., SHAW B. I., DIMITROKALLIS N., BARBAS A. S. Organ Donation During the Coronavirus Pandemic: An Evolving Saga in Uncharted Waters. Transpl. Int., 2020.
MAGGI U., DE CARLIS L., YIU D., COLLEDAN M., REGALIA E., ROSSI G. et al. The impact of the COVID-19 outbreak on Liver Transplantation programmes in Northern Italy. Am. J. Transplant., 2020.
LANTHIER N., MOREELS T. G. The future of Acta Gastro-Enterologica Belgica. Acta Gastroentero. Belg., 2019, 82: 3-4.
MOREELS T. G., LANTHIER N. The quest for quality. Acta Gastroentero. Belg., 2018, 81: 3-4.
PAN L., ZENG J., YANG H. Challenges and countermeasures for organ donation during the SARS-CoV-2 epidemic: the experience of Sichuan Provincial People’s Hospital. Intensive Care Med., 2020, 1-2.
BOYARSKY B. J., CHIANG T. P., WERBEL W. A., DURAND C. M., AVERY R. K., GETSIN S. N. et al. Early Impact of COVID-19 on Transplant Center Practices and Policies in the United States. Am. J. Transplant., 2020.
Belgium transplantation society and the national transplant council guidelines, viewed April 28 2020, https://www.basl.be/wp-content/uploads/2020/04/BTS_NTC_position-statement-transplantation-COVID_final.pdf.
AHMAD J., DOWNEY K. K., AKOAD M., CACCIARELLI T. V. Impact of the MELD score on waiting time and disease severity in liver transplantation in United States veterans. Liver Transpl., 2007, 13: 1564-1569.
MOECKLI B., PELOSO A., OLDANI G., ORCI L. A., BANZ V., DUTKOWSKI P. et al. The Swiss approach to the COVID-19 outbreak. Am. J. Transplant., 2020.
FIX O. K., HAMEED B., FONTANA R. J., KWOK R. M., MCGUIRE B. M., MULLIGAN D. C. et al. Clinical Best Practice Advice for Hepatology and Liver Transplant Providers During the COVID-19 Pandemic: AASLD Expert Panel Consensus Statement. Hepatology, 2020.
WEBB G. J., MOON A. M., BARNES E., BARRITT A. S., MARJOT T. Determining risk factors for mortality in liver transplant patients with COVID-19. Lancet Gastroenterol. Hepatol., 2020: S2468-1253(2420)30125-30124.
LAGANA S. M., DE MICHELE S., LEE M. J., EMOND J. C., GRIESEMER A. D., TULIN-SILVER S. A. et al. COVID-19 Associated Hepatitis Complicating Recent Living Donor Liver Transplantation. Arch. Pathol. Lab. Med., 2020.
MEHTA P., MCAULEY D. F., BROWN M., SANCHEZ E., TATTERSALL R. S., MANSON J. J. COVID-19: consider cytokine storm syndromes and immunosuppression. The Lancet, 2020, 395: 1033-1034.
