Article (Scientific journals)
Recommendations for the surgical treatment of endometriosis. Part 2: deep endometriosis.
Keckstein, Joerg; Becker, Christian M.; Canis, Michel et al.
2020In Human Reproduction Open, 2020 (1), p. 002
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Keywords :
deep endometriosis; endometriosis; extrapelvic; frozen pelvis; good practice recommendations; hysterectomy; laparoscopy; surgery
Abstract :
[en] STUDY QUESTION: How should surgery for endometriosis be performed? SUMMARY ANSWER: This document provides recommendations covering technical aspects of different methods of surgery for deep endometriosis in women of reproductive age. WHAT IS KNOWN ALREADY: Endometriosis is highly prevalent and often associated with severe symptoms. Yet compared to equally prevalent conditions, it is poorly understood and a challenge to manage. Previously published guidelines have provided recommendations for (surgical) treatment of deep endometriosis, based on the best available evidence, but without technical information and details on how to best perform such treatment in order to be effective and safe. STUDY DESIGN SIZE DURATION: A working group of the European Society for Gynaecological Endoscopy (ESGE), ESHRE and the World Endometriosis Society (WES) collaborated on writing recommendations on the practical aspects of surgery for treatment of deep endometriosis. PARTICIPANTS/MATERIALS SETTING METHODS: This document focused on surgery for deep endometriosis and is complementary to a previous document in this series focusing on endometrioma surgery. MAIN RESULTS AND THE ROLE OF CHANCE: The document presents general recommendations for surgery for deep endometriosis, starting from preoperative assessments and first steps of surgery. Different approaches for surgical treatment are discussed and are respective of location and extent of disease; uterosacral ligaments and rectovaginal septum with or without involvement of the rectum, urinary tract or extrapelvic endometriosis. In addition, recommendations are provided on the treatment of frozen pelvis and on hysterectomy as a treatment for deep endometriosis. LIMITATIONS REASONS FOR CAUTION: Owing to the limited evidence available, recommendations are mostly based on clinical expertise. Where available, references of relevant studies were added. WIDER IMPLICATIONS OF THE FINDINGS: These recommendations complement previous guidelines on management of endometriosis and the recommendations for surgical treatment of ovarian endometrioma. STUDY FUNDING/COMPETING INTERESTS: The meetings of the working group were funded by ESGE, ESHRE and WES. Dr Roman reports personal fees from ETHICON, PLASMASURGICAL, OLYMPUS and NORDIC PHARMA, outside the submitted work; Dr Becker reports grants from Bayer AG, Volition Rx, MDNA Life Sciences and Roche Diagnostics Inc. and other relationships or activities from AbbVie Inc., and Myriad Inc, during the conduct of the study; Dr Tomassetti reports non-financial support from ESHRE, during the conduct of the study; and non-financial support and other were from Lumenis, Gedeon-Richter, Ferring Pharmaceuticals and Merck SA, outside the submitted work. The other authors had nothing to disclose. TRIAL REGISTRATION NUMBER: na.
Disciplines :
Reproductive medicine (gynecology, andrology, obstetrics)
Author, co-author :
Keckstein, Joerg
Becker, Christian M.
Canis, Michel
Feki, Anis
Grimbizis, Grigoris F.
Hummelshoj, Lone
Nisolle, Michelle ;  Université de Liège - ULiège > Département des sciences cliniques > Gynécologie - Obstétrique
Roman, Horace
Saridogan, Ertan
Tanos, Vasilios
Tomassetti, Carla
Ulrich, Uwe A.
Vermeulen, Nathalie
De Wilde, Rudy Leon
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Title :
Recommendations for the surgical treatment of endometriosis. Part 2: deep endometriosis.
Publication date :
Journal title :
Human Reproduction Open
Publisher :
Oxford University Press, United Kingdom
Volume :
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Pages :
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
© The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology.
Available on ORBi :
since 08 July 2020


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