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A Simplified Waveform Energetics Approach to Interpreting Arterial and Venous Pressure
Davidson, S. M.; Balmer, J.; Pretty, C. et al.
2018In IFAC-PapersOnLine, 51 (27), p. 140-145
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Keywords :
Bio-signal analysis; Cardiovascular system; Decision support systems; Artificial intelligence; Blood pressure; Processing; Clinical interventions; Diagnostic potential; False positive rates; Novel methodology; Pressure attenuation; Pressure waveforms; Systemic circulation
Abstract :
[en] This paper develops a novel methodology for extracting simple, beat-to-beat, lumped metrics of systemic circulation performance by comparing the catheter pressure waveforms from the femoral artery and vena cava. Their diagnostic potential is compared to the similar, clinically used metric ΔMP, the drop in mean blood pressure between the aorta and vena cava, across an experimental cohort encompassing the progression of sepsis and several clinical interventions known to alter circulatory state. Both Ofe→vc, the model derived pressure attenuation between the femoral artery and vena cava, and the clinical metric, ΔMP, performed well. However, Ofe→vc reduced the optimal average time to sepsis detection from endotoxin infusion from 46.2 minutes for ΔMP to 11.6 minutes, for a slight increase in false positive rate from 1.8% to 6.2%. Thus, the potential diagnostic benefits of this novel approach are demonstrated, and a case is made for further investigation. © 2018
Disciplines :
Engineering, computing & technology: Multidisciplinary, general & others
Anesthesia & intensive care
Author, co-author :
Davidson, S. M.;  Department of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand
Balmer, J.;  Department of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand
Pretty, C.;  Department of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand
Desaive, Thomas  ;  Université de Liège - ULiège > Département d'astrophys., géophysique et océanographie (AGO) > Thermodynamique des phénomènes irréversibles
Chase, J. G.;  Department of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand
Language :
English
Title :
A Simplified Waveform Energetics Approach to Interpreting Arterial and Venous Pressure
Publication date :
2018
Event name :
BMS 2018
Event date :
3-5 septembre 2018
Audience :
International
Journal title :
IFAC-PapersOnLine
ISSN :
2405-8971
eISSN :
2405-8963
Publisher :
Elsevier B.V.
Volume :
51
Issue :
27
Pages :
140-145
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 08 June 2020

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