Article (Scientific journals)
Comparison of the Susceptibility of the Red Fox (Vulpes Vulpes) to a Vaccinia-Rabies Recombinant Virus and to Cowpox Virus
Boulanger, Denise; Brochier, Bernard; Crouch, A. et al.
1995In Vaccine, 13 (2), p. 215-9
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Keywords :
Rabies virus; cowpox virus; recombination risk
Abstract :
[en] Sylvatic rabies can be efficiently controlled by vaccination of foxes with a vaccinia-rabies recombinant virus. However, the risk of recombination between the engineered vaccine virus and other orthopoxviruses endemic in wildlife, such as cowpox virus, still needs to be investigated. In this study, foxes inoculated orally and intradermally with cowpox virus were found to be not very susceptible to cowpox virus, which was isolated from only the oropharynx and tonsils, at low titre and for only five days after inoculation. Thus the risk of recombination between these viruses in foxes is very low.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Boulanger, Denise;  Université de Liège - ULiège > Faculty of Veterinary Medicine > Immunology-Vaccinology
Brochier, Bernard;  Université de Liège - ULiège > Faculty of Veterinary Medicine > Immunology-Vaccinology
Crouch, A.;  University of Liverpool > Veterinary Clinical Science
Bennett, M.;  University of Liverpool > Veterinary Pathology
Gaskell, R. M.;  University of Liverpool > Veterinary Clinical Science
Baxby, D.;  University of Liverpool > Medical Microbiology
Pastoret, Paul-Pierre ;  Université de Liège - ULiège > Faculty of Veterinary Medicine > Immunology-Vaccinology
Language :
English
Title :
Comparison of the Susceptibility of the Red Fox (Vulpes Vulpes) to a Vaccinia-Rabies Recombinant Virus and to Cowpox Virus
Publication date :
February 1995
Journal title :
Vaccine
ISSN :
0264-410X
eISSN :
1873-2518
Publisher :
Elsevier, Netherlands
Volume :
13
Issue :
2
Pages :
215-9
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 12 May 2020

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