Aptamer-based biosensor for detection of mycotoxins

Guo, Xiaodong; Wen, Fang; Zheng, Nan; Saive, Matthew; Fauconnier, Marie-Laure; Wang, Jiaqi

doi:10.3389/fchem.2020.00195

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Aptamer-based biosensor for detection of mycotoxins

Guo, Xiaodong; Wen, Fang; Zheng, Nan et al.

2020 • In Frontiers in Chemistry, 8, p. 195

Peer Reviewed verified by ORBi

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https://hdl.handle.net/2268/246742

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10.3389/fchem.2020.00195

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Keywords :

mycotoxin; aptamer; biosensor; detection; food safety

Abstract :

[en] Mycotoxins are a large types of secondary metabolites appeared by fungi, they pose a great hazard and toxic reactions to human and animals. A majority of countries and regulators, such as European Union, have established series of requirements and set the maximum tolerated levels. The development of high sensitive and specific analytical platform for mycotoxins is much in demand to address new challenges for food safety in worldwide. Due to the superiority of simple, rapid, and low-cost characteristics, aptamer-based biosensors are successfully developed for the detection of various mycotoxins with high sensitivity and selectivity compared with traditional instrumental methods and immunological approaches. In this article, we discuss and analyze the development of aptasensors for mycotoxins determination in food and agricultural products during the last eleven years and cover the literatures from the first report in 2008 until today. In addition, challenges and future trends for the selection of aptamers towards various mycotoxins and aptasensors for multi-mycotoxins analysis are summarized. Given the promising development and potential application of aptasensors, the future researches will witness the great practicability of aptamer-based biosensor for food safety field.

Disciplines :

Chemistry
Food science

Author, co-author :

Guo, Xiaodong

Wen, Fang

Zheng, Nan

Saive, Matthew

Fauconnier, Marie-Laure ; Université de Liège - ULiège > Département GxABT > Chimie des agro-biosystèmes

Wang, Jiaqi

Language :

English

Title :

Aptamer-based biosensor for detection of mycotoxins

Publication date :

03 March 2020

Journal title :

Frontiers in Chemistry

eISSN :

2296-2646

Publisher :

Frontiers Media S.A., Lausanne, Switzerland

Volume :

Pages :

art. 195

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

https://www.frontiersin.org/articles/10.3389/fchem.2020.00195/full

Name of the research project :

Project of risk assessment on raw milk (GJFP2019026)
Agricultural Science and Technology Innovation Program (ASTIP-IAS12)

Funders :

NSCF - National Natural Science Foundation of China
Modern Agro Industry Technology Research System of the PR China (CARS-36)

Funding number :

Special Fund for Agroscientific Research in the Public Interest (201403071)

Available on ORBi :

since 21 April 2020

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