Article (Scientific journals)
A MOVING RESIDUAL LIMB: BOTULINUM TOXIN TO THE RESCUE
Briand, Marie-Michèle; Boudier-Réverêt, Mathieu; Rodrigue, Xavier et al.
2020In Translational Neuroscience
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Keywords :
Amputation stump; myoclonus; movement disorders; Botulinum toxin
Abstract :
[en] Movement disorders post-amputation are a rare complication and can manifest as the jumping stump phenomenon, a form of peripheral myoclonus. The pathophysiology remains unknown and there is currently no standardized treatment. We describe the case of a 57-year-old male with unremitting stump myoclonus, starting one month after transtibial amputation, in his residual limb without associated phantom or neurological pain. The consequence of the myoclonus was a reduction in prosthetic wearing time. Failure to respond to oral medication led us to attempt the use of botulinum neurotoxin Type A injections in the involved muscles of the residual limb. Injection trials, over a two-year period, resulted in an improvement of movement disorder, an increased prosthetic wearing time and a higher satisfaction level of the patient. Injection of botulinum toxin type A should be considered as an alternative treatment for stump myoclonus to improve prosthetic wearing time and comfort.
Disciplines :
Neurology
Author, co-author :
Briand, Marie-Michèle ;  Université de Liège - ULiège > Consciousness-Coma Science Group
Boudier-Réverêt, Mathieu;  University of Montreal Health Center > Department of Physical Medicine and Rehabilitation
Rodrigue, Xavier;  Institut de réadaptation en déficience physique de Québec
Sirois, Geneviève;  Institut de réadaptation en déficience physique de Québec
Chang, Min Cheol;  College of Medicine, Yeungnam University, Namku, Taegu, Republic of Korea. > Department of Physical Medicine and Rehabilitation
Language :
English
Title :
A MOVING RESIDUAL LIMB: BOTULINUM TOXIN TO THE RESCUE
Publication date :
2020
Journal title :
Translational Neuroscience
ISSN :
2081-3856
eISSN :
2081-6936
Publisher :
De Gruyter Open, Poland
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 14 February 2020

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