[en] An environmentally-friendly process to prepare well-defined cross-linked particles of poly(2-hydroxyethyl methacrylate) (PHEMA) was investigated. The dispersion polymerisation of 2-hydroxyethyl methacrylate (HEMA) with a cross-linker ethylene glycol dimethacrylate (EGDMA) was performed in supercritical carbon dioxide (scCO2). Stabilisers based only on vinyl acetate (VAc) and vinyl pivalate (VPi) random copolymers P(VAc-stat-VPi) were employed thus avoiding the use of silicone or fluorine based stabilisers which are normally required in scCO2. The effect of molecular weight and composition of the P(VAc-stat-VPi) stabil- isers on the size and shape of the produced microparticles was investigated. A copolymer stabiliser with 56 : 44 (VAc : VPi) molar composition (Mn = 12.8 kg mol−1) was found to be the most efficient, resulting in well-defined spherical cross-linked PHEMA particles with a diameter of 1.2 µm. This particular stabiliser was found to provide good steric stabilisation for a range of cross-linker ratios and the addition of a co- monomer such as N-vinylpyrrolidone (NVP) allowed tuning of the properties of the microparticulate pro- ducts. Finally, the stabiliser plays a second very important role. Partial hydrolysis of the ester groups of the stabiliser located on the surface of the microparticles leads to a hydrophilic surface with alcohol moieties and hence facilitates dispersion of the microparticles into water leading to valuable microgels.
Introduction
Research Center/Unit :
Complex and Entangled Systems from Atoms to Materials (CESAM) Research Unit Center for Education and Research on Macromolecules (CERM)
Disciplines :
Materials science & engineering Chemistry
Author, co-author :
Parilti, Rahmet; University of Liège (ULiège), Complex and Entangled Systems from Atoms to Materials (CESAM) Research Unit, Center for Education and Research on Macromolecules (CERM), Belgium > University of Nottingham, School of Chemistry, UK
Castañon, Alba; University of Nottingham, School of Chemistry, UK
Lansalot, Muriel; University Claude Bernard Lyon 1, Villeurbane, Chemistry, Catalysis, Polymers & Processes (C2P2), France
D'Agosto, Franck; University Claude Bernard Lyon 1, Villeurbane, Chemistry, Catalysis, Polymers & Processes (C2P2), France
Jérôme, Christine ; University of Liège (ULiège), Complex and Entangled Systems from Atoms to Materials (CESAM) Research Unit, Center for Education and Research on Macromolecules (CERM), Belgium
Howdle, Steven M.; University of Nottingham, School of Chemistry, UK
Language :
English
Title :
Hydrocarbon based stabilisers for the synthesis of cross-linked poly(2-hydroxyethyl methacrylate) particles in supercritical carbon dioxide
Publication date :
14 November 2019
Journal title :
Polymer Chemistry
ISSN :
1759-9954
eISSN :
1759-9962
Publisher :
Royal Society of Chemistry, United Kingdom
Volume :
10
Issue :
42
Pages :
5760-5770
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
The European Joint Doctorat Program in the frame of Nanofar
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