Unexpected field observations and transmission dynamics of contagious caprine pleuropneumonia in a sand gazelle herd

[en] Contagious caprine pleuropneumonia (CCPP), caused by Mycoplasma capricolum subsp. capripneumoniae, has long been considered a goat-specific disease. Since 2007 there has been growing evidence that this disease can affect wild ungulates either kept in captivity or in the wild. In 2013, a large collection of sand gazelles (Gazella marica) held in the United Arab Emirates suffered heavy losses due to a CCPP epizootic confirmed by PCR and isolation. Animals displayed typical lesions, with unilateral pneumonia and profuse pleurisy. An initial antibiotic treatment consisting of tylosin administered in drinking water did not improve the animals’ condition and vaccination failed to stop the spread to contiguous pens. A treatment with tetracycline mixed in feed pellets finally succeeded to stop the evolution of the disease. A subsequent vaccine trial, performed on naïve animals, showed that only a reference CCPP vaccine produced according to OIE standards induced a sero-conversion by CCPP competition ELISA, while the commercially available vaccines did not. A SEIRD compartment transmission model was developed to better understand the dynamics of the disease. The parameters were initially set as per expert opinion and then adjusted to fit the observed mortality data. The basic reproductive number R0 was estimated to be between 2.3–2.7, while the final mortality rate reached up to 70% in some pens. Transmission of infectious droplets from an external source, through a distance of at least the 50 m separating the pens from the perimeter fence, remains the most plausible explanation for the contamination of this stock of gazelles. © 2018 Elsevier B.V.

Disciplines :

Veterinary medicine & animal health

Author, co-author :

Lignereux, Louis ; Faculty of Veterinary Medicine, University of Liège, Unit of Epidemiology and risk analysis applied to veterinary sciences (UREAR-ULg), Fundamental and Applied Research for Animal and Health (FARAH) Center, Quartier Vallée 2, Avenue de Cureghem 7A, Bât. B42, (Sart-Tilman), Liège, Belgium

Chaber, Anne-Lise ; Université de Liège - ULiège > Département des maladies infectieuses et parasitaires (DMI) > Epidémiologie et analyse des risques appl. aux sc. vétér.

Saegerman, Claude ; Université de Liège - ULiège > Département des maladies infectieuses et parasitaires (DMI) > Epidémiologie et analyse des risques appl. aux sc. vétér.

Manso-Silván, Lucía; Centre de coopération internationale en recherche agronomique pour le développement (CIRAD), Institut National de Recherche Agronomique (INRA), AnimalS, health, Territories, Risks and Ecosystems (ASTRE), TA A-117/E Campus international de Baillarguet, Montpellier cedex 05, France

Peyraud, Armelle; Centre de coopération internationale en recherche agronomique pour le développement (CIRAD), Institut National de Recherche Agronomique (INRA), AnimalS, health, Territories, Risks and Ecosystems (ASTRE), TA A-117/E Campus international de Baillarguet, Montpellier cedex 05, France

Apolloni, Andrea; Centre de coopération internationale en recherche agronomique pour le développement (CIRAD), Institut National de Recherche Agronomique (INRA), AnimalS, health, Territories, Risks and Ecosystems (ASTRE), TA A-117/E Campus international de Baillarguet, Montpellier cedex 05, France, Institut Sénégalais de Recherches Agricoles, Laboratoire National de l'Elevage et de Recherche Vétérinaire, Parc Scientifique de Hann, Dakar, Senegal

Thiaucourt, François; Centre de coopération internationale en recherche agronomique pour le développement (CIRAD), Institut National de Recherche Agronomique (INRA), AnimalS, health, Territories, Risks and Ecosystems (ASTRE), TA A-117/E Campus international de Baillarguet, Montpellier cedex 05, France

Language :

English

Title :

Unexpected field observations and transmission dynamics of contagious caprine pleuropneumonia in a sand gazelle herd

Publication date :

2018

Journal title :

Preventive Veterinary Medicine

ISSN :

0167-5877

eISSN :

1873-1716

Publisher :

Elsevier B.V.

Volume :

157

Pages :

70-77

Peer reviewed :

Peer Reviewed verified by ORBi

Funders :

MoEFCC - Ministry of Environment, Forests and Climate Change

Available on ORBi :

since 01 January 2020

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