Article (Scientific journals)
A life-course and multifactorial approach to Alzheimer’s disease: Implications for research, clinical assessment and intervention practices
Van der Linden, Martial; Juillerat Van der Linden, Anne-Claude
2018In Dementia, 17 (7), p. 880-895
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Keywords :
Alzheimer’s disease; Alzheimer disease; Biomedical Research; Humans
Abstract :
[en] According to the dominant biomedical view, Alzheimer’s disease (AD) has a precise, necessary and unifying neurobiological cause, which distinguishes it from other neurodegenerative diseases and normal ageing. However, different types of evidence specifically lead to questioning the foundations of this essentialist and category-based approach to AD. It seems more and more evident that AD represents a heterogeneous state, determined by multiple factors and mechanisms that interact and intervene throughout life. This other way of conceiving AD not only requires a change of research objectives, but also a profound modification of clinical assessment and intervention practices. It also appeals to follow the path of prevention. © The Author(s) 2016.
Disciplines :
Neurosciences & behavior
Author, co-author :
Van der Linden, Martial ;  Université de Liège - ULiège > Département de Psychologie > Département de Psychologie
Juillerat Van der Linden, Anne-Claude;  University of Geneva, Switzerland
Language :
English
Title :
A life-course and multifactorial approach to Alzheimer’s disease: Implications for research, clinical assessment and intervention practices
Publication date :
2018
Journal title :
Dementia
ISSN :
1471-3012
eISSN :
1741-2684
Publisher :
SAGE, London, United Kingdom
Volume :
17
Issue :
7
Pages :
880-895
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 29 December 2019

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