The Age-Well observational study on expert meditators in the Medit-Ageing European project

Aging; Alzheimer's disease; Blood markers; Cognition; Compassion and loving-kindness meditation; Dementia; Emotion; Lifestyle; Meditation expertise; Mindfulness meditation; Neuroimaging; Prevention; Reserve; Sleep

Abstract :

[en] Introduction: The Age-Well observational, cross-sectional study investigates the affective and cognitive mechanisms of meditation expertise with behavioral, neuroimaging, sleep, and biological measures sensitive to aging and Alzheimer's disease (AD). Methods: Thirty cognitively unimpaired individuals aged 65 years or older with at least 10,000 hours of practice in mindfulness meditation (MM) and loving-kindness and compassion meditation (LKCM) are selected. The outcomes are the neuroimaging brain correlates of MM and LKCM and the assessments of long-term meditation practices on behavioral, neural, and biological measures as compared to nonmeditator older controls from the Age-Well randomized controlled trial. Results: Recruitment and data collection began in late 2016 and will be completed by late 2019. Discussion: Results are expected to foster the understanding of the effects of meditation expertise on aging and of the mechanisms of action underlying the meditation intervention in the Age-Well randomized controlled trial. These finding will contribute to the design of meditation-based prevention randomized controlled trials for the aged population and to the exploration of the possible long-time developmental trajectory of meditation training. © 2018 The Authors

Research Center/Unit :

GIGA CRC (Cyclotron Research Center) In vivo Imaging-Aging & Memory - ULiège
INSERM - Institut National de la Santé et de la Recherche Médicale

Disciplines :

Neurosciences & behavior

Author, co-author :

Lutz, Antoine; Lyon Neuroscience Research Center INSERM U1028, CNRS UMR5292, Lyon University, Lyon, France

Klimecki, Olga; Swiss Center for Affective Sciences, Department of Medicine and Department of Psychology, University of Geneva, Geneva, Switzerland

Collette, Fabienne ; Université de Liège - ULiège > Département de Psychologie > Neuropsychologie

Poisnel, Géraldine; Université Normandie, Inserm, Université de Caen-Normandie, Inserm UMR-S U1237, GIP Cyceron, Caen, France

Arenaza-Urquijo, Eider; Université Normandie, Inserm, Université de Caen-Normandie, Inserm UMR-S U1237, GIP Cyceron, Caen, France

Marchant, Natalie; Division of Psychiatry, University College London, London, United Kingdom

De La Sayette, Vincent; Université Normandie, Inserm, Université de Caen-Normandie, Inserm UMR-S U1077, GIP Cyceron, Caen, France, CHU Caen-Normandie, Department of Clinical Research, Caen, France

Rauchs, Géraldine; Université Normandie, Inserm, Université de Caen-Normandie, Inserm UMR-S U1077, GIP Cyceron, Caen, France

Salmon, Eric ; Université de Liège - ULiège > Département des sciences cliniques > Neuroimagerie des troubles de la mémoire et révalid. cogn.

Vuilleumier, Patrik; Department of Medicine, University of Geneva, Geneva, Switzerland

More authors (4 more)

Language :

English

Title :

The Age-Well observational study on expert meditators in the Medit-Ageing European project

Publication date :

2018

Journal title :

Alzheimer's and Dementia: Translational Research and Clinical Interventions

eISSN :

2352-8737

Publisher :

Elsevier Inc

Volume :

Pages :

756-764

Peer reviewed :

Peer Reviewed verified by ORBi

European Projects :

H2020 - 667696 - MEDIT-AGEING - Investigating the impact of meditation training on mental health and wellbeing in the ageing population

Funders :

EGU - European Geosciences Union
Conseil Régional de Haute Normandie
CE - Commission Européenne

Available on ORBi :

since 19 December 2019

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