Metabolomics toward a personalized approach of vascular diseases

Personalized medicine could be described as the study of the most appropriate and tailored way to treat patients. This promising paradigm change in medicine care aims to place the patient at the center of the medical management and is expected to significantly improve the quality of life of the patient and to reduce the healthcare cost and the duration of hospital stay. It must combine modern and innovative tools to measure, integrate and model informative data that could help clinicians. Because it provides a unique insight into the relationships between physiological status, lifestyle, pathologies and patients, and because it correlates with a patient’s disease phenotype, metabolomics is particularly adapted to obtain relevant and helpful information for a personalized approach to treatment. Even if vascular care has evolved enormously in the last decades, with the development of innovative surgery and endovascular techniques, the improvement of the diagnostics tools and the optimization of new treatments, cardiovascular diseases (CVD) remain linked to a high prevalence and mortality. Then, application of an innovative personalized approach of CVD is mandatory and metabolomics represents clearly a well-adapted and powerful tool. This area of metabolomics is clearly emerging and, even if the number of studies involving “omics” sciences in CVD still remains limited in comparison with other pathologies such as cancer, cardiovascular metabolomics studies are notably in progression.