Effects of botulinum toxin A therapy and multidisciplinary rehabilitation on upper and lower limb spasticity in post-stroke patients.

Hara, Takatoshi; Abo, Masahiro; Hara, Hiroyoshi; Kobayashi, Kazushige; Shimamoto, Yusuke; Samizo, Yuta; Sasaki, Nobuyuki; Yamada, Naoki; Niimi, Masachika

doi:10.1080/00207454.2016.1196204

Article (Scientific journals)

Effects of botulinum toxin A therapy and multidisciplinary rehabilitation on upper and lower limb spasticity in post-stroke patients.

Hara, Takatoshi; Abo, Masahiro; Hara, Hiroyoshi et al.

2017 • In The International journal of neuroscience, 127 (6), p. 469-478

Peer reviewed

Permalink
https://hdl.handle.net/2268/241462

DOI
10.1080/00207454.2016.1196204

PubMed
27256591

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Keywords :

Aged; Botulinum Toxins, Type A/therapeutic use; Female; Follow-Up Studies; Humans; Lower Extremity/physiopathology; Male; Middle Aged; Muscle Spasticity/drug therapy/rehabilitation; Neuromuscular Agents/therapeutic use; Retrospective Studies; Stroke/complications; Stroke Rehabilitation/methods; Treatment Outcome; Upper Extremity/physiopathology; botulinum toxin A therapy; multidisciplinary rehabilitation; stroke

Abstract :

[en] OBJECTIVES: The purpose of this study was to examine the effects of combined botulinum toxin type A (BoNT-A) and inpatient multidisciplinary (MD) rehabilitation therapy on the improvement of upper and lower limb function in post-stroke patients. METHODS: In this retrospective study, a 12-day inpatient treatment protocol was implemented on 51 post-stroke patients with spasticity. Assessments were performed on the day of admission, at discharge, and at 3 months following discharge. RESULTS: At the time of discharge, all of the evaluated items showed a statistically significant improvement. Only the Functional Reach Test (FRT) showed a statistically significant improvement at 3 months. In subgroup analyses, the slowest walking speed group showed a significantly greater change ratio of the 10 Meter Walk Test relative to the other groups, from the time of admission to discharge. This group showed a greater FRT change ratio than the other groups from the time of admission to the 3-month follow-up. CONCLUSION: Inpatient combined therapy of simultaneous injections of BoNT-A to the upper and lower limbs and MD may improve motor function.

Disciplines :

Neurology

Author, co-author :

Hara, Takatoshi

Abo, Masahiro

Hara, Hiroyoshi

Kobayashi, Kazushige

Shimamoto, Yusuke

Samizo, Yuta

Sasaki, Nobuyuki

Yamada, Naoki

Niimi, Masachika ; Université de Liège - ULiège > Consciousness-Coma Science Group

Language :

English

Title :

Effects of botulinum toxin A therapy and multidisciplinary rehabilitation on upper and lower limb spasticity in post-stroke patients.

Publication date :

2017

Journal title :

The International journal of neuroscience

ISSN :

0020-7454

eISSN :

1563-5279

Volume :

127

Issue :

Pages :

469-478

Peer reviewed :

Peer reviewed

Available on ORBi :

since 19 November 2019

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