mortality; falls; balance; nutrition; nursing home issues
Résumé :
[en] Background: This study aimed to evaluate the predictive value of the domains of intrinsic capacity (ie, cognition, locomotion, sensory, vitality, and psychosocial) proposed by the World Health Organization (WHO) on the 3-year adverse health outcomes of nursing home residents.
Methods: A 3-year incidence of mortality, falls, repeated falls, and autonomy decline (ie, a one-unit increase in the Katz score) was assessed in a cohort of Belgian nursing home residents. Cognition was assessed using the Mini-Mental State Examination (MMSE). For locomotion, balance, gait speed and chair stand performance were evaluated by the Short Physical Performance Battery test. The sensory domain was measured using the Strawbridge questionnaire for audition and vision. For vitality, abdominal circumference, body mass index, nutritional status (by Mini Nutritional Assessment [MNA]) and handgrip strength were assessed. Psychosocial status was evaluated by the EQ-5D and the Center for Epidemiological Studies Depression scale. Missing data were handled by multiple imputations. Cox proportional hazard models, logistic regressions, and analysis of variance were used for the analyses.
Results: In the multivariable model, a one-unit increase in balance performance and in the nutrition score decreased the probability of death by 12% (Hazard ratio [HR] = 0.88; 95% confidence interval [CI] 0.78–0.99) and 4% (HR = 0.96; 95% CI 0.93–0.99), respectively. The risk of falling decreased when there was a one-unit increase in balance performance (HR = 0.87, 95% CI 0.79–0.96) and in the nutrition score (HR = 0.96, 95% CI 0.93–0.98). No association was found for intrinsic capacity and repeated falls. Low scores in nutrition (odds ratio = 0.86,
95% CI 0.77–0.96) were associated with a higher probability of autonomy decline.
Conclusion: Some domains of intrinsic capacity predicted health outcomes among nursing home residents. Nutrition and balance should be regularly checked among this population.
Disciplines :
Santé publique, services médicaux & soins de santé
Auteur, co-auteur :
Charles, Alexia ; Université de Liège - ULiège > Département des sciences de la santé publique > Epidémiologie clinique
Buckinx, Fanny ; Université de Liège - ULiège > Département des sciences de la santé publique > Département des sciences de la santé publique
Locquet, Médéa ; Université de Liège - ULiège > Département des sciences de la santé publique > Epidémiologie clinique
Reginster, Jean-Yves ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Petermans, Jean ; Centre Hospitalier Universitaire de Liège - CHU > Département de médecine interne > Service de gériatrie
Gruslin, Bastien ; Université de Liège - ULiège > Master sc. santé publ., à finalité
Bruyère, Olivier ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Langue du document :
Anglais
Titre :
Prediction of adverse outcomes in nursing home residents according to intrinsic capacity proposed by the World Health Organization
Date de publication/diffusion :
2020
Titre du périodique :
Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Carvalho IA De, Martin FC, Cesari M, Sumi Y, Thiyagarajan JA, Beard J. Operationalising the concept of intrinsic capacity in clinical settings. Background paper for the WHO Working Group on Metrics and Research Standards for Healthy Ageing. 2017.
WHO Clinical Consortium on Healthy Ageing 2017 - report of consortium meeting, 21-22 November, 2017 in Geneva, Switzerland. Geneva: World Health Organization; 2018.
Cesari M, Araujo de Carvalho I, Amuthavalli Thiyagarajan J, et al. Evidence for the domains supporting the construct of intrinsic capacity. J Gerontol A Biol Sci Med Sci. 2018; 73:1653-1660. doi:10.1093/gerona/gly011
Thiyagarajan JA, Cesari M, Kumar S, et al. Diagnostic Accuracy of Screening Tool for Non- Specialist Health Care Settings : A Summary of Findings from ICOPE Rapid Reviews. Geneva, Switzerland: World Health Organization; 2017.
Cooper R, Kuh D, Hardy R; Mortality Review Group; FALCon and HALCyon Study Teams. Objectively measured physical capability levels and mortality: Systematic review and meta-analysis. BMJ. 2010; 341:c4467. doi:10.1136/bmj.c4467
Gill TM, Williams CS, Richardson ED, Tinetti ME. Impairments in physical performance and cognitive status as predisposing factors for functional dependence among nondisabled older persons. J Gerontol A Biol Sci Med Sci. 1996; 51:M283-M288. doi:10.1093/gerona/51a.6.m283
Reed-Jones RJ, Solis GR, Lawson KA, Loya AM, Cude-Islas D, Berger CS. Vision and falls: A multidisciplinary review of the contributions of visual impairment to falls among older adults. Maturitas. 2013; 75:22-28. doi:10.1016/j.maturitas.2013.01.019
Schillerstrom JE, Royall DR, Palmer RF. Depression, disability and intermediate pathways: A review of longitudinal studies in elders. J Geriatr Psychiatry Neurol. 2008; 21:183-197. doi: 10.1177/0891988708320971
Ramírez-vélez R, Izquierdo M, Correa-bautista JE, García-hermoso A, Cano CA. Reference values for handgrip strength and their association with intrinsic capacity domains among older adults. 2019; 57:278-286. doi:10.1002/jcsm.12373.
Buckinx F, Reginster JY, Petermans J, et al. Relationship between frailty, physical performance and quality of life among nursing home residents: The SENIOR cohort. Aging Clin Exp Res. 2016; 28:1149-1157. doi:10.1007/s40520-016-0616-4
Jeon M, Gu MO, Yim J. Comparison of walking, muscle strength, balance, and fear of falling between repeated fall group, one-time fall group, and nonfall group of the elderly receiving home care service. Asian Nurs Res (Korean Soc Nurs Sci). 2017; 11:290-296. doi:10.1016/j. anr.2017.11.003
Katz S, Ford AB, Moskowitz RW, Jackson BA, Jaffe MW. Studies of Illness in the Aged The index of ADL : A standardized measure of biological and psychosocial function. JAMA. 1963; 95:914. doi:10.1001/jama.1963.03060120024016
Tombaugh TN, McIntyre NJ. The mini-mental state examination: A comprehensive review. J Am Geriatr Soc. 1992; 40:922-935. doi:10.1111/j.1532-5415.1992.tb01992.x
Simonsick EM, Blazer DG. A short physical performance battery assessing lower extremity function : Association with self-reported disability and prediction of mortality and nursing home admission a short physical performance battery assessing lower extremi. J Gerontol. 1994; 49:85-94. doi:10.1093/geronj/49.2.M85.
Matthews M, Lucas A, Boland R, et al. Use of a questionnaire to screen for frailty in the elderly: An exploratory study. Aging Clin Exp Res. 2004; 16:34-40. doi:10.1007/BF03324529
Roberts HC, Denison HJ, Martin HJ, et al. A review of the measurement of grip strength in clinical and epidemiological studies: Towards a standardised approach. Age Ageing. 2011; 40:423-429. doi:10.1093/ageing/afr051
Villars H, Hospitalier C, Toulouse U De, Soto M, Guigoz Y, Morley JE. Overview of the MNA - Its history and challenges. J Nutr Heal Aging. 2005; 10(6):456-463.
Radloff LS. The CES-D scale : A self-report depression scale for research in the general population. Appl Psychol Meas. 1977; 1:385-401. doi:10.1177/014662167700100306.
Schafer J. Analysis of Incomplete Multivariate Data. Chapman & . London; 1997.
Nowak E, Oger E, Mottier D. Études d 'observation : Cas-témoins et cohorte. Médecine thérapeutique [France]. 2008; 14:37-46. doi:10.1684/met.2008.0148.
Legrand D, Vaes B, Matheï C, Adriaensen W, Van Pottelbergh G, Degryse JM. Muscle strength and physical performance as predictors of mortality, hospitalization, and disability in the oldest old. J Am Geriatr Soc. 2014; 62:1030-1038. doi:10.1111/jgs.12840
Turusheva A, Frolova E, Hegendoerfer E, Degryse JM. Predictors of shortterm mortality, cognitive and physical decline in older adults in northwest Russia: A population-based prospective cohort study. Aging Clin Exp Res. 2017; 29:665-673. doi:10.1007/s40520-016-0613-7
Nofuji Y, Shinkai S, Taniguchi Y, et al. Associations of walking speed, grip strength, and standing balance with total and cause-specific mortality in a general population of Japanese elders. J Am Med Dir Assoc. 2016; 17:184. e1-184.e7. doi:10.1016/j.jamda.2015.11.003
Donini LM, Felice MR De, Paolini M, Scavone L. Predicting the outcome of long-term care by clinical and functional indices : The role of nutritional status. J Nutr Health Aging. 2011; 15:586-592. doi:10.1007/s12603-011-0030-8.
Choe Y, Joh J, Sunwoo D, Kim Y. Interaction between frailty and nutritional status on mortality and long-term hospitalization in older Koreans : A retrospective analysis of data from the 2008 survey on health and welfare status of the elderly in Korea. Arch Gerontol Geriatr. 2018; 76:106-113. doi:10.1016/j.archger.2018.01.011
Lilamand M, Kelaiditi E, Demougeot L, Rolland Y, Vellas B, Cesari M. The mini nutritional assessment-short form and mortality in nursing home residents-results from the INCUR study. J Nutr Health Aging. 2015; 19:383-388. doi:10.1007/s12603-014-0533-1
Trevisan C, Crippa A, Ek S, et al. Nutritional status, body mass index, and the risk of falls in community-dwelling older adults: A systematic review and meta-analysis. J Am Med Dir Assoc. 2019; 20:569-582.e7. doi:10.1016/j.jamda.2018.10.027
Khater MS, Mousa SM. Predicting falls among Egyptian nursing home residents: A 1-year longitudinal study. J Clin Gerontol Geriatr. 2012; 3:73-76. doi:10.1016/j.jcgg.2012.04.005
Lannering C, Ernsth Bravell M, Midlöv P, Östgren CJ, Mölstad S. Factors related to falls, weight-loss and pressure ulcers-more insight in risk assessment among nursing home residents. J Clin Nurs. 2016; 25:940-950. doi: 10.1111/jocn.13154
Bürge E, von Gunten A, Berchtold A. Factors favoring a degradation or an improvement in activities of daily living (ADL) performance among nursing home (NH) residents: A survival analysis. Arch Gerontol Geriatr. 2013; 56:250-257. doi: 10.1016/j.archger.2012.09.001
Sugiura Y, Tanimoto Y, Imbe A, et al. Association between functional capacity decline and nutritional status based on the nutrition screening initiative checklist: A 2-year Cohort study of Japanese community-dwelling elderly. PLoS One. 2016; 11:e0166037. doi:10.1371/journal.pone.0166037
Martínez-Reig M, Gómez-Arnedo L, Alfonso-Silguero SA, Juncos-Martínez G, Romero L, Abizanda P. Nutritional risk, nutritional status and incident disability in older adults. The FRADEA study. J Nutr Health Aging. 2014; 18:270-276. doi:10.1007/s12603-013-0388-x
Buckinx F, Croisier JL, Reginster JY, et al. Prediction of the incidence of falls and deaths among elderly nursing home residents: The SENIOR Study. J Am Med Dir Assoc. 2018; 19:18-24. doi:10.1016/j. jamda.2017.06.014.
Donini LM, Poggiogalle E, Molfino A, et al. Mini-nutritional assessment, malnutrition universal screening tool, and nutrition risk screening tool for the nutritional evaluation of older nursing home residents. J Am Med Dir Assoc. 2016; 17:959.e11-959.e18. doi:10.1016/j.jamda.2016.06.028
Seematter-Bagnoud L, Büla C. Brief assessments and screening for geriatric conditions in older primary care patients: A pragmatic approach. Public Health Rev. 2018; 39:8. doi:10.1186/s40985-018-0086-7
Hewitt J, Goodall S, Clemson L, Henwood T, Refshauge K. Progressive resistance and balance training for falls prevention in long-term residential aged care: A cluster randomized trial of the sunbeam program. J Am Med Dir Assoc. 2018; 19:361-369. doi:10.1016/j.jamda.2017.12.014
Tsuboi M, Momosaki R, Vakili M, Abo M. Nutritional supplementation for activities of daily living and functional ability of older people in residential facilities: A systematic review. Geriatr Gerontol Int. 2018; 18:197-210. doi:10.1111/ggi.13160
Veronese N, Stubbs B, Punzi L, et al. Effect of nutritional supplementations on physical performance and muscle strength parameters in older people: A systematic review and meta-analysis. Ageing Res Rev. 2019; 51:48-54. doi:10.1016/j.arr.2019.02.005
Integrated Care for Older People: Guidelines on Community-Level Interventions to Manage Declines in Intrinsic Capacity. Geneva, Switzerland: World Health Organization; 2017.
