Tnf-Alpha and Ifn-Gamma Down-Regulate the Expression of the Metastasis-Associated Bi-Functional 37lrp/P40 Gene and Protein in Transformed Keratinocytes - 1998
Tnf-Alpha and Ifn-Gamma Down-Regulate the Expression of the Metastasis-Associated Bi-Functional 37lrp/P40 Gene and Protein in Transformed Keratinocytes
Clausse, Nathalie; van den Brûle, Frédéric; Delvenne, Philippeet al.
1998 • In Biochemical and Biophysical Research Communications, 251 (2), p. 564-9
[en] The 37 LRP/p40 molecule is a bi-functional protein in which expression is increased in a large variety of cancers in association with their metastatic phenotype. Here we present the first data concerning the 37 LRP/p40 gene promoter activity and show that it is very active in a cervix carcinoma cell line. Interestingly, despite hallmarks of a housekeeping gene, we show that the 37 LRP/p40 gene promoter can be down-regulated by two potentially anticancerous cytokines, TNF-alpha and IFN-gamma. In addition, the dual fate of the protein, i.e., being intracellularly involved in the cell translation machinery and incorporated into a 67-kDa cell surface protein functioning as a laminin receptor (67LR), is differentially affected by the treatment. Our data suggest multiple regulation levels in the control of the 67LR/37LRP/p40 molecule expression and uncover new clues for the understanding of both the control of expression of this metastasis-associated molecule and the IFN-gamma and TNF-alpha anticancerous action.
Disciplines :
Oncologie
Auteur, co-auteur :
Clausse, Nathalie
van den Brûle, Frédéric
Delvenne, Philippe ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques
Jacobs, Nathalie ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques
Franzen-Detrooz, Elisabeth
Jackers, Pascale ; Université de Liège - ULiège > Centre interfac. d'analyse des résidus en traces (CART)
Castronovo, Vincenzo ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biologie générale et cellulaire
Langue du document :
Anglais
Titre :
Tnf-Alpha and Ifn-Gamma Down-Regulate the Expression of the Metastasis-Associated Bi-Functional 37lrp/P40 Gene and Protein in Transformed Keratinocytes
Date de publication/diffusion :
20 octobre 1998
Titre du périodique :
Biochemical and Biophysical Research Communications
ISSN :
0006-291X
eISSN :
1090-2104
Maison d'édition :
Elsevier, Atlanta, Etats-Unis - Californie
Volume/Tome :
251
Fascicule/Saison :
2
Pagination :
564-9
Peer reviewed :
Peer reviewed
Organisme subsidiant :
CAC - Centre anticancéreux près l'Université de Liège asbl Association Sportive contre le Cancer F.R.S.-FNRS - Fonds de la Recherche Scientifique
Dagher S. F., Wang J. L., Patterson R. J. Proc. Natl. Acad. Sci. USA. 92:1995;1213-1217.
Yang R. Y., Hsu D. K., Liu F. T. Proc. Natl. Acad. Sci. USA. 93:1996;6737-6742.
Akahani S., Nangia-Makker P., Inohara H., Kim H. R., Raz A. Cancer Res. 57:1997;5272-5276.
Perillo N. L., Pace K. E., Seilhamer J. J., BAum L. G. Nature. 378:1995;736-739.
Menard S., Castronovo V., Tagliabue E., Sobel M. E. J. Cell. Biochem. 67:1997;155-165.
Clausse N., Jackers P., Jares P., Joris B., M. E. S., Castronovo V. DNA Cell. Biol. 15:1996;1009-1023.
Clausse N., Jackers P., Castronovo V. Belg. J. Zool. 127:1997;3-11.
Wewer U. M., Liotta L. A., Jaye M., Ricca G. A., Drohan W. N., Claysmith A. P., Rao C. N., Wirth P., Coligan J. E., Albrechtsen R. Proc. Natl. Acad. Sci. USA. 83:1986;7137-7141.
Yow H., Weng J. M., Chen H. S., Lee C., Steel G. D. J., Chen L. B. Proc. Natl. Acad. Sci. USA. 85:1988;6394-6398.
Castronovo V., Claysmith A. P., Barker K. T., Cioce V., Krutzsch H. C., Sobel M. E. Biochem. Biophys. Res. Commun. 177:1991;177-183.
Rao C. N., Castronovo V., Schmitt M. C., Wewer U. M., Claysmith A. P., Liotta L. A., Sobel M. E. Biochemistry. 28:1989;7476-7486.
Ardini E., Pesole G., Tagliabue E., Magnifico A., Castronovo V., Sobel M. E., Menard S. Mol. Biol. Evol. 1998.
Makrides S., Chitpatima S. T., Bandyopadhyay R., Brawerman G. Nucleic Acid Res. 16:1988;2349.
Tohgo A., Takasawa S., Munkata H., Yonekura H., Hayashi N., Okamoto H. FEBS Lett. 340:1994;133-138.
Rosenthal E. T., Wordeman L. J. Cell Sci. 108:1995;245-256.
Cioce V., Castronovo V., Shmookler B. M., Garbisa S., Grigioni W. F., Liotta L. A., Sobel M. E. J. Natl. Cancer Inst. 83:1991;29-36.
Campo E., Monteagudo C., Castronovo V., Claysmith A. P., Fernandez P. L., Sobel M. E. Am. J. Pathol. 141:1992;1073-1083.
Castronovo V., Campo E., Van den brule F., Claysmith A. P., Cioce V., Liu F.-T., Fernandez P. L., Sobel M. E. Articles. 84:1992;1161-1169.
Kondoh N., Schweinfest C. W., Henderson K. W., Papas T. S. Cancer Res. 52:1992;791-796.
Martignone S., Ménard S., Bufalino R., Cascinelli N., Pellegrini R., Tagliabue E., Andreola S., Rilke F., Colnaghi M. I. J. Natl. Cancer Inst. 85:1993;398-402.
Sobel M. E. Cancer Biol. 4:1993;311-317.
van den Brûle F. A., Berchuck A., Bast R. C., Liu F.-T., Gillet C., Sobel M. E., Castronovo V. Eur. J. Cancer. 30A:1994;1096-1099.
Gasparini G., Barbareschi M., Boracchi P., Bevilacqua P., Verderio P., Dalla Palma P., Ménard S. Int. J. Cancer. 60:1995;604-610.
Pellegrini R., Martignone S., Tagliabue E., Belotti D., Bufalino R., Cascinelli N., Ménard S., Colnaghi M. I. Breast Cancer Res. Treatment. 35:1995;195-199.
van den Brûle F. A., Castronovo V., Ménard S., Giavazzi R., Marzola M., Belotti D., Taraboletti G. Eur. J. Cancer. 32A:1996;1598-1602.
Waltregny D., de Leval L., Menard S., de Leval J., Castronovo V. J. Natl. Cancer Inst. 89:1997;1224-1227.
Jackers P., Minoletti F., Belotti D., Clausse N., Sozzi G., Sobel M. E., Castronovo V. Oncogene. 13:1996;495-503.
Al-Saleh W., Delvenne P., van den Brûle F. A., Ménard S., Boniver J., Castronovo V. J. Pathol. 181:1997;287-293.
Delvenne P., Al-Saleh W., Gilles C., Thiry A., Boniver J. Am. J. Pathol. 146:1995;589-597.
Friedl F., Kimura I., Osato T., Ito Y. Proc. Soc. Exp. Biol. Med. 135:1970;543-545.
Pater M., Pater A. Virology. 145:1985;313-318.
Biochemistry. 18:1979;5294-5299.
Gunning P., Ponte P., Okayama H., Engel J., Blau H., Kedes L. Mol. Cell. Biol. 3:1983;787-795.
Buto S. Int. J. Biol. Markers. 12:1997;1-5.
Frigeri L. G., Liu F. J. Immunol. 148:1992;861-867.
Martignone S., Pellegrini R., Villa E., Tandon N. N., Mastroianni A., Tagliabue E., Ménard S., Bufalino R., Colnaghi M. I. Clin. Exp. Metast. 10:1992;379-386.
Jackers P., Clausse N., Fernandez M. T., Berti A., Princen F., Wewer U., Sobel M. E., Castronovo V. Biochem. Biophys. Acta. 1305:1996;98-104.
Raitano A. B., Korc M. J. Biol. Chem. 265:1990;10466-10472.
Pandita R., Pocsik E., Aggarwal B. B. FEBS Lett. 312:1992;87-90.
Min W., Ghosh S., Lengyel P. Mol. Cell. Biol. 16:1996;359-368.
Akashi M., Shaw G., Gross M., Saito M., Koeffler P. Blood. 78:1991;2005-2012.
Mitchell T. J., Naughton M., Norsworthy P., Davies K., Walport M. J., Morley B. J. J. Immunol. 1996.
Castronovo V. Invasion Metastasis. 13:1993;1-30.
Pierandrei-Amaldi P., Amaldi F. Genetica. 94:1994;181-193.
Pellizzoni L., Lotti F., Maras B., Pirandrei-Amaldi P. J. Mol. Biol. 267:1997;264-275.
Landowski T. H., Dratz E. A., Starkey J. R. Biochemistry. 34:1995;11276-11287.
