Reference : Reduced Glutathione System: Role in Cancer Development, Prevention and Treatment (Review)
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
Human health sciences : Oncology
Reduced Glutathione System: Role in Cancer Development, Prevention and Treatment (Review)
Locigno, R. [> > > >]
Castronovo, Vincenzo mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biologie générale et cellulaire >]
International Journal of Oncology
Yes (verified by ORBi)
[en] glutathione ; GSH ; antioxidant ; cancer
[en] Reduced glutathione (GSH), a ubiquitous thiol-containing tripeptide, is unanimously recognized to play a central role in cell biology. It is highly implicated in the cellular defense against xenobiotics and naturally occurring deleterious compounds such as free radicals and hydroperoxides. Consequently, GSH is an essential actor in several human diseases including cancer and cardio-vascular diseases. Its implication in oncogenesis has led to the development of new strategies to improve both prevention and treatment of cancer. The present review proposes an in depth analysis or our current knowledge of the relations between GSH and cancer.
Biodynamics (Ostende, Belgium)

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