No full text
Article (Scientific journals)
Reduced Glutathione System: Role in Cancer Development, Prevention and Treatment (Review)
Locigno, R.; Castronovo, Vincenzo
2001In International Journal of Oncology, 19 (2), p. 221-36
Peer Reviewed verified by ORBi
 

Files


Full Text
No document available.

Send to



Details



Keywords :
glutathione; GSH; antioxidant; cancer
Abstract :
[en] Reduced glutathione (GSH), a ubiquitous thiol-containing tripeptide, is unanimously recognized to play a central role in cell biology. It is highly implicated in the cellular defense against xenobiotics and naturally occurring deleterious compounds such as free radicals and hydroperoxides. Consequently, GSH is an essential actor in several human diseases including cancer and cardio-vascular diseases. Its implication in oncogenesis has led to the development of new strategies to improve both prevention and treatment of cancer. The present review proposes an in depth analysis or our current knowledge of the relations between GSH and cancer.
Disciplines :
Biochemistry, biophysics & molecular biology
Oncology
Author, co-author :
Locigno, R.
Castronovo, Vincenzo ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biologie générale et cellulaire
Language :
English
Title :
Reduced Glutathione System: Role in Cancer Development, Prevention and Treatment (Review)
Publication date :
August 2001
Journal title :
International Journal of Oncology
ISSN :
1019-6439
eISSN :
1791-2423
Publisher :
Demetrios A. Spandidos Ed. & Pub., Greece
Volume :
19
Issue :
2
Pages :
221-36
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
Biodynamics (Ostende, Belgium)
Available on ORBi :
since 28 September 2009

Statistics


Number of views
90 (1 by ULiège)
Number of downloads
0 (0 by ULiège)

Scopus citations®
 
83
Scopus citations®
without self-citations
83
OpenCitations
 
7

Bibliography


Similar publications



Contact ORBi