Multitasking abilities in adolescents with 22q11.2 deletion syndrome: Results from an experimental ecological paradigm

Adolescents; Multitasking; Negative symptoms; Real-world functioning; DiGeorge syndrome; Adolescent; Attention; Case-Control Studies; Child; Executive Function; Female; Humans; Male; Neuropsychological Tests; Task Performance and Analysis; Young Adult

Abstract :

[en] The 22q11.2 deletion syndrome (22q11.2DS) is associated with cognitive and functional impairments and increased risk for schizophrenia. We characterized multitasking abilities of adolescents with 22q11.2DS using an experimental naturalistic setting and examined whether multitasking impairments were associated with real-world functioning and negative symptoms. Thirty-nine adolescents (19 with 22q11.2DS and 20 controls) underwent the Multitasking Evaluation for Adolescents. Real-world functioning and clinical symptoms were assessed in participants with 22q11.2DS. Adolescents with 22q11.2DS performed poorly in the multitasking evaluation. Our data also suggest that multitasking abilities are related to adaptive functioning in the practical domain and negative symptoms. This study shows that adolescents with 22q11.2DS are characterized by multitasking impairments, which may be relevant for several aspects of the clinical phenotype. © AAIDD.

Disciplines :

Neurosciences & behavior

Author, co-author :

Schneider, Maude; Université de Genève - UNIGE > Department of Psychiatry, School of Medicine, and Cognitive Psychopathology and Neuropsychology Unit, Faculty of Psychology and Educational Sciences

Eliez, Stephan; Université de Genève - UNIGE > Department of Psychiatry, Department of Genet ic Medicine and Development, School of Medicine

Birr, Julie; Université de Genève - UNIGE > Department of Psychiatry

Menghetti, Sarah; Université de Genève - UNIGE > Department of Psychiatry

Debbané, Martin; Université de Genève - UNIGE > Adolescence Clinical Psychology Research Unit

Van der Linden, Martial ; Université de Liège - ULiège > Département de Psychologie

Language :

English

Title :

Multitasking abilities in adolescents with 22q11.2 deletion syndrome: Results from an experimental ecological paradigm

Publication date :

2016

Journal title :

American Journal on Intellectual and Developmental Disabilities

ISSN :

1944-7515

eISSN :

1944-7558

Publisher :

American Association on Intellectual and Developmental Disabilities, United States

Volume :

121

Issue :

Pages :

151-164

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 31 October 2019

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