Article (Scientific journals)
Precision medicine in airway diseases: moving to clinical practice
Agustí, A.; Bafadhel, M.; Beasley, R. et al.
2017In European Respiratory Journal, 50 (4)
Peer Reviewed verified by ORBi
 

Files


Full Text
AGUSTI 2017_ Precision medicine in airways diseases_Eur Respir J_OCR.pdf
Author postprint (856.21 kB)
Download
Full Text Parts
AGUSTI 2017_ Precision medicine in airways diseases_Eur Respir J_ppediteur.pdf
Publisher postprint (580 kB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Europe; Asthma; Biomarkers; Classification; Congresses as Topic; Genotype; Humans; Phenotype; Practice Patterns, Physicians'; Precision Medicine; Pulmonary Disease, Chronic Obstructive; Research; Societies, Medical
Abstract :
[en] On February 21, 2017, a European Respiratory Society research seminar held in Barcelona discussed how to best apply precision medicine to chronic airway diseases such as asthma and chronic obstructive pulmonary disease. It is now clear that both are complex and heterogeneous diseases, that often overlap and that both require individualised assessment and treatment. This paper summarises the presentations and discussions that took place during the seminar. Specifically, we discussed the need for a new taxonomy of human diseases, the role of different players in this scenario (exposome, genes, endotypes, phenotypes, biomarkers and treatable traits) and a number of unanswered key questions in the field. We also addressed how to deploy airway precision medicine in clinical practice today, both in primary and specialised care. Finally, we debated the type of research needed to move the field forward. Copyright ©ERS 2017.
Disciplines :
Cardiovascular & respiratory systems
Author, co-author :
Agustí, A.;  Respiratory Institute, Hospital Clínic, Institut d'Investigacions Biomédiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain AAGUSTI@clinic.cat, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Spain
Bafadhel, M.;  Dept of Respiratory Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK
Beasley, R.;  Medical Research Institute of New Zealand, Wellington, New Zealand
Bel, E. H.;  Dept of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, The Netherlands
Faner, R.;  Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Spain
Gibson, P. G.;  The Centre of Excellence in Severe Asthma, Priority Research Centre for Healthy Lungs, The University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia
Louis, Renaud ;  Université de Liège - ULiège > Département des sciences cliniques > Pneumologie - Allergologie
McDonald, V. M.;  The Centre of Excellence in Severe Asthma, Priority Research Centre for Healthy Lungs, The University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia
Sterk, P. J.;  Dept of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, The Netherlands
Thomas, M.;  Primary Care and Population Sciences, University of Southampton, Aldermoor Health Centre, Southampton, UK
Vogelmeier, C.;  University of Marburg, Member of the German Center for Lung Research (DZL), Marburg, Germany
Pavord, I. D.;  Dept of Respiratory Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK, Oxford NIHR Biomedical Research Centre, University of Oxford and Oxford University Hospitals NHS Foundation Trust, Oxford, UK
Language :
English
Title :
Precision medicine in airway diseases: moving to clinical practice
Publication date :
19 October 2017
Journal title :
European Respiratory Journal
ISSN :
0903-1936
eISSN :
1399-3003
Publisher :
European Respiratory Society, Lausanne, Switzerland
Volume :
50
Issue :
4
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 12 October 2019

Statistics


Number of views
53 (3 by ULiège)
Number of downloads
97 (1 by ULiège)

Scopus citations®
 
135
Scopus citations®
without self-citations
84
OpenCitations
 
120

Bibliography


Similar publications



Contact ORBi