Article (Scientific journals)
Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis – A EUFOREA-ARIA-EPOS-AIRWAYS ICP statement
Hellings, P. W.; Fokkens, W. J.; Bachert, C. et al.
2017In Allergy, 72 (9), p. 1297-1305
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Keywords :
Article
Abstract :
[en] Precision medicine (PM) is increasingly recognized as the way forward for optimizing patient care. Introduced in the field of oncology, it is now considered of major interest in other medical domains like allergy and chronic airway diseases, which face an urgent need to improve the level of disease control, enhance patient satisfaction and increase effectiveness of preventive interventions. The combination of personalized care, prediction of treatment success, prevention of disease and patient participation in the elaboration of the treatment plan is expected to substantially improve the therapeutic approach for individuals suffering from chronic disabling conditions. Given the emerging data on the impact of patient stratification on treatment outcomes, European and American regulatory bodies support the principles of PM and its potential advantage over current treatment strategies. The aim of the current document was to propose a consensus on the position and gradual implementation of the principles of PM within existing adult treatment algorithms for allergic rhinitis (AR) and chronic rhinosinusitis (CRS). At the time of diagnosis, prediction of success of the initiated treatment and patient participation in the decision of the treatment plan can be implemented. The second-level approach ideally involves strategies to prevent progression of disease, in addition to prediction of success of therapy, and patient participation in the long-term therapeutic strategy. Endotype-driven treatment is part of a personalized approach and should be positioned at the tertiary level of care, given the efforts needed for its implementation and the high cost of molecular diagnosis and biological treatment. © 2017 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.
Disciplines :
Cardiovascular & respiratory systems
Author, co-author :
Hellings, P. W.;  Department of Otorhinolaryngology-Head and Neck Surgery, UZ Leuven, Leuven, Belgium, Department of Otorhinolaryngology, Academic Medical Center, Amsterdam, Netherlands, Department of Otorhinolaryngology-Head and Neck Surgery, Upper Airways Research Laboratory, Ghent University, Ghent, Belgium
Fokkens, W. J.;  Department of Otorhinolaryngology, Academic Medical Center, Amsterdam, Netherlands
Bachert, C.;  Department of Otorhinolaryngology-Head and Neck Surgery, Upper Airways Research Laboratory, Ghent University, Ghent, Belgium, Department of Otorhinolaryngology, Karolinska Institute, Stockholm, Sweden
Akdis, C. A.;  Swiss Institute of Allergy and Asthma Research (SIAF), Christine-Kühne Center for Allergy Research and Education, University of Zurich, Davos, Switzerland
Bieber, T.;  Department of Dermatology and Allergy, Christine Kühne-Center for Allergy Research and Education, Friedrich-Wilhelms-University, Bonn, Germany
Agache, I.;  Faculty of Medicine, Transylvania University, Brasov, Romania
Bernal-Sprekelsen, M.;  Department of Otorhinolaryngology, Hospital Clínic Universitari, Barcelona, Spain
Canonica, G. W.;  Department of Biomedical Science, Personalized Medicine Clinic Asthma & Allergy, Humanitas Clinical and Research Center, Humanitas University - Rozzano (Milano), Rozzano, Italy
Gevaert, P.;  Department of Otorhinolaryngology-Head and Neck Surgery, Upper Airways Research Laboratory, Ghent University, Ghent, Belgium
Joos, G.;  Department of Respiratory Medicine, Ghent University, Ghent, Belgium
Lund, V.;  Royal National Throat, Nose and Ear Hospital, University College London Hospitals, London, United Kingdom
Muraro, A.;  Department of Women and Child Health, Food Allergy Referral Centre Veneto Region, Padua General University Hospital, Padua, Italy
Onerci, M.;  Department of Otorhinolaryngology Head and Neck Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey
Zuberbier, T.;  Department of Dermatology and Allergy, Comprehensive Allergy-Centre-Charité, Charité-Universitätsmedizin Berlin, Berlin, Germany
Pugin, B.;  European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA), Brussels, Belgium
Seys, S. F.;  European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA), Brussels, Belgium, Department of Immunology and Microbiology, Laboratory of Clinical Immunology, KU Leuven, Leuven, Belgium
Bousquet, J.;  Department of Respiratory Disease, University Hospital Arnaud de Villeneuve, Montpellier, France
ARIA and EPOS working groups
Aberer, W.
Agache, I.
Akdis, C. A.
Akdis, M.
Alobid, I.
Ankri, J.
Annesi-Maesano, I.
Ansotegui, I. J.
Anto, J. M.
Arnavielhe, S.
Arshad, H.
Asarnoj, A.
Avolio, F.
Bachert, C.
Bachert, C.
Baiardini, I.
Barbagallo, M.
Barbara, C.
Baroody, F.
Bateman, E. D.
Bedbrook, A.
Beghé, B.
Bel, E. H.
Bennoor, K. S.
Benson, M.
Bergmann, K. C.
Bewick, M.
Bialoszewski, A. Z.
Bieber, T.
Bindslev-Jensen, C.
Bjermer, L.
Blain, H.
Blasi, F.
Boner, A. L.
Bonini, M.
Bonini, S.
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Bosse, I.
Bouchard, J.
Boulet, L. P.
Bourret, R.
Bousquet, J.
Bousquet, P. J.
Braido, F.
Briggs, A. H.
Brightling, C. E.
Brozek, J.
Bucca, C.
Buhl, R.
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Burte, E.
Bush, A.
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Calderon, M. A.
Camargos, P. A.
Camuzat, T.
Canonica, G. W.
Cardona, V.
Carlsen, K. H.
Carr, W.
Carreiro-Martins, P.
Carriazo, A. M.
Casale, T.
Cepeda Sarabia, A. M.
Cervin, A.
Cesari, M.
Chatzi, L.
Chavannes, N. H.
Chiron, R.
Chivato, T.
Chkhartishvili, E.
Chuchalin, A. G.
Chung, K. F.
Ciprandi, G.
Cohen, N.
Conzález Diaz, S.
Cox, L.
Crooks, G.
Cruz, A. A.
Custovic, A.
Dahl, R.
Dahlen, S. E.
Darsow, U.
De Carlo, G.
De Manuel Keenoy, E.
de Sousa, J. C.
De Vries, G.
Dedeu, T.
Deleanu, D.
Demoly, P.
Denburg, J. A.
Devillier, P.
Didier, A.
Dinh-Xuan, A. T.
Dokic, D.
Douagui, H.
Douglas, R.
Dray, G.
Du Toit, G.
Dubakiene, R.
Durham, S. R.
Dykewicz, M. S.
Eklund, P.
El-Gamal, Y.
Ellers, E.
Emuzyte, R.
Farrell, J.
Fink Wagner, A.
Fiocchi, A.
Fletcher, M.
Fokkens, W. J.
Fonseca, J.
Forastiere, F.
Gaga, M.
Gamkrelidze, A.
Gemicioğlu, B.
Georgalas, C.
Gereda, J. E.
Gevaert, P.
Goossens, H.
Grisle, I.
Guldemond, N. A.
Gutter, Z.
Guzmán, M. A.
Haahtela, T.
Harvey, R.
Heinrich, J.
Hellings, P. W.
Hellings, P. W.
Hellquist-Dahl, B.
Hopkins, C.
Horak, F.
Hourihane, J. O.
Humbert, M.
Hyland, M.
Iaccarino, G.
Illario, M.
Jares, E. J.
Jeandel, C.
Johnston, S. L.
Jonquet, O.
Joos, G.
Joos, G.
Jung, K. S.
Just, J.
Jutel, M.
Kaidashev, I.
Kalayci, O.
Kalogjera, L.
Kalyoncu, A. F.
Kardas, P.
Keil, T.
Keith, P. K.
Kerkhof, M.
Kern, B.
Kerstjens, H. A.
Khaitov, M.
Khaltaev, N.
Klimek, L.
Kogevinas, M.
Kolek, V.
Koppelman, G. H.
Kowalski, M.
Kowalski, M. L.
Kuitunen, M.
Kull, I.
Kuna, P.
Kvedariene, V.
Lambrecht, B.
Larenas-Linnemann, D.
Lau, S.
Laune, D.
Le, L. T.
Li, Jianwei
Lieberman, P.
Lipworth, B.
Lodrup Carlsen, K. C.
Louis, Renaud ;  Université de Liège - ULiège > Département des sciences cliniques > Pneumologie - Allergologie
Lund, V. J.
Lupinek, C.
MacNee, W.
Magar, Y.
Magnan, A.
Mahboub, B.
Maier, D.
Majer, I.
Malva, J.
Manning, P.
Marshall, G. D.
Masjedi, M. R.
Mathieu-Dupas, E.
Maurer, M.
Mavale-Manuel, S.
Melén, E.
Melo-Gomes, E.
Meltzer, E. O.
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Merk, H.
Miculinic, N.
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Milenkovic, B.
Millot-Keurinck, J.
Mohammad, Y.
Momas, I.
Morais-Almeida, M.
Mösges, R.
Mullol, J.
Mullol, J.
Muraro, A.
Murray, R.
Naclerio, R.
Nadif, R.
Namazova-Baranova, L.
Neffen, H.
Nekam, K.
Nieto, A.
Niggemann, B.
Nogueira-Silva, L.
Nogues, M.
Nyembue, T. D.
O'Hehir, R. E.
Ohta, K.
Okamoto, Y.
Okubo, K.
Olive-Elias, M.
Ouedraogo, S.
Paggiaro, P.
Pali-Schöll, I.
Palkonen, S.
Panzner, P.
Papadopoulos, N. G.
Papi, A.
Park, H. S.
Passalacqua, G.
Pawankar, R.
Pedersen, S.
Pfaar, O.
Picard, R.
Pigearias, B.
Pin, I.
Plavec, D.
Pohl, W.
Popov, T. A.
Portejoie, F.
Postma, D.
Potter, P.
Poulsen, L. K.
Price, D.
Price, D.
Rabe, K. F.
Raciborski, F.
Riechelmann, H.
Robalo-Cordeiro, C.
Roberts, G.
Rodenas, F.
Rodriguez-Mañas, L.
Rolland, C.
Roman Rodriguez, M.
Romano, A.
Rosado-Pinto, J.
Rosario, N.
Rottem, M.
Ryan, D.
Samolinski, B.
Sanchez-Borges, M.
Sastre-Dominguez, J.
Scadding, G. K.
Schlosser, R.
Schmid-Grendelmeier, P.
Schunemann, H. J.
Scichilone, N.
Senior, B.
Serrano, E.
Sheikh, A.
Shields, M.
Simons, F. E. R.
Siroux, V.
Sisul, J. C.
Skrindo, I.
Smit, H. A.
Solé, D.
Sooronbaev, T.
Spranger, O.
Stellato, C.
Stelmach, R.
Sterk, P. J.
Strandberg, T.
Sunyer, J.
Thijs, C.
Thomas, M.
Todo-Bom, A.
Tomazic, P. V.
Toskala, E.
Triggiani, M.
Valenta, R.
Valero, A.
Valiulis, A.
Valovirta, E.
van Eerd, M.
van Ganse, E.
van Hage, M.
van Wick, R. G.
Vandenplas, O.
Varona, L. L.
Vazankari, T.
Vellas, B.
Ventura, M. T.
Vezzani, G.
Viegi, G.
Voegels, R.
Vontetsianos, T.
Wagenmann, M.
Wahn, U.
Walker, S.
Wang, D. Y.
Wang, Y.
Werfel, T.
Whalley, B.
Wickman, M.
Williams, D. M.
Williams, S.
Wilson, N.
Wormald, P. J.
Wright, J.
Yawn, B. P.
Yiallouros, P. K.
Yorgancioglu, A.
Young, I.
Yusuf, O. M.
Zaidi, A.
Zar, H. J.
Zernotti, M. E.
Zhang, L.
Zhong, N.
Zidarn, M.
Zuberbier, T.
More authors (346 more) Less
Language :
English
Title :
Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis – A EUFOREA-ARIA-EPOS-AIRWAYS ICP statement
Publication date :
September 2017
Journal title :
Allergy
ISSN :
0105-4538
eISSN :
1398-9995
Publisher :
Blackwell Publishing Ltd
Volume :
72
Issue :
9
Pages :
1297-1305
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
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