First report of a successful pediatric heart transplantation from donation after circulatory death with distant procurement using normothermic regional perfusion and cold storage.
cold static storage; donation after circulatory death; heart transplantation; normothermic regional perfusion; organ donation; organ transplantation
Abstract :
[en] Heart transplantation (HT) from donation after circulatory death (DCD) is a promising alternative to expand the heart donor pool. Cold storage can be used in a strategy to successfully retrieve and transplant DCD hearts after reconditioning using normothermic regional perfusion for distant procurement. Herein, we present the first report of a pediatric DCD heart reconditioned with normothermic regional perfusion, preserved using only cold storage while being transported to a neighboring center, and then successfully transplanted after nearly 2 hours of cold static storage. If supported by an appropriate trial, this finding could obviate the need to use expensive perfusion devices for short interhospital distances for DCD heart transportation and stimulate more centers across the world to embrace DCD HT.
Disciplines :
Anesthesia & intensive care Cardiovascular & respiratory systems Surgery
Author, co-author :
Tchana-Sato, Vincent ; Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
Ledoux, Didier ; Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
Vandendriessche, Katrien
Van Cleemput, Johan
Hans, Grégory ; Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
ANCION, Arnaud ; Centre Hospitalier Universitaire de Liège - CHU > Département de médecine interne > Insuffisance cardiaque - Transplantation
Cools, Bjorn
AMABILI, Philippe ; Centre Hospitalier Universitaire de Liège - CHU > Département d'Anesthésie et réanimation > Service d'anesthésie - réanimation
DETRY, Olivier ; Centre Hospitalier Universitaire de Liège - CHU > Département de chirurgie > Chirurgie abdo, sénologique, endocrine et de transplantation
MASSION, Paul ; Centre Hospitalier Universitaire de Liège - CHU > Autres Services Médicaux > Service des soins intensifs
MONARD, Josée ; Centre Hospitalier Universitaire de Liège - CHU > Département de chirurgie > Chirurgie abdo, sénologique, endocrine et de transplantation
DELBOUILLE, Marie-Hélène ; Centre Hospitalier Universitaire de Liège - CHU > Département de chirurgie > Chirurgie abdo, sénologique, endocrine et de transplantation
Meyns, Bart
Defraigne, Jean-Olivier ; Université de Liège - ULiège > Département des sciences cliniques > Chirurgie cardio-vasculaire et thoracique
First report of a successful pediatric heart transplantation from donation after circulatory death with distant procurement using normothermic regional perfusion and cold storage.
Publication date :
October 2019
Journal title :
Journal of Heart and Lung Transplantation
ISSN :
1053-2498
eISSN :
1557-3117
Volume :
38
Issue :
10
Pages :
1112-1115
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
Copyright (c) 2019 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.
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