Growth Benefits of Own Mother's Milk in Preterm Infants Fed Daily Individualized Fortified Human Milk.

de HALLEUX, Virginie; PIELTAIN, Catherine; SENTERRE, Thibault; Studzinski, Frédéric; Kessen, Catheline; Rigo, Vincent; Rigo, Jacques

doi:10.3390/nu11040772

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Growth Benefits of Own Mother's Milk in Preterm Infants Fed Daily Individualized Fortified Human Milk.

de HALLEUX, Virginie; PIELTAIN, Catherine; SENTERRE, Thibault et al.

2019 • In Nutrients, 11 (4), p. 772

Peer Reviewed verified by ORBi

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https://hdl.handle.net/2268/239501

DOI
10.3390/nu11040772

PubMed
30987136

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Keywords :

donor milk; fortification; growth; human milk; own mother's milk; preterm

Abstract :

[en] The influence of types of human milk (HM)-raw own mother's milk (OMM), pasteurized OMM, and donor milk (DM)-was evaluated for growth in premature infants fed exclusively HM with controlled nutritional intakes using daily individualized HM fortification (IHMF). Growth and nutritional intakes were prospectively collected in preterm infants (<32 weeks) fed IHMF and compared in infants fed predominantly (>/=75%) OMM and DM. The influence of HM types (raw OMM, pasteurized OMM, and DM) on growth were also evaluated in the whole population. One-hundred and one preterm infants (birth weight 970 +/- 255 g, gestational age 27.8 +/- 1.9 weeks) were included. Energy (143 +/- 8 vs. 141 +/- 6 kcal/kg/day; p = 0.15) and protein intakes (4.17 +/- 0.15 vs. 4.15 +/- 0.14 g/kg/day; p = 0.51) were similar in both groups. Infants receiving predominantly OMM (n = 37), gained significantly more weight (19.8 +/- 2.0 vs. 18.2 +/- 2.2 g/kg/day; p = 0.002) and length (1.17 +/- 0.26 vs. 0.99 +/- 0.36 cm/week; p = 0.020) than those fed predominantly DM (n = 33). Stepwise multivariate analysis (n = 101) suggests that raw OMM was the major determinant of growth, contributing 22.7% of weight gain. Length gain was also related to OMM (raw + pasteurized) intakes, explaining 4.0% of length gain. In conclusion, at daily controlled similar protein and energy intakes, OMM had significant beneficial effects on weight and length versus DM in VLBW infants. This difference could be partially explained by the use of raw OMM.

Disciplines :

Endocrinology, metabolism & nutrition
Pediatrics

Author, co-author :

de HALLEUX, Virginie ; Centre Hospitalier Universitaire de Liège - CHU > Département de Pédiatrie > Service néonatologie (CHR)

PIELTAIN, Catherine ; Centre Hospitalier Universitaire de Liège - CHU > Département de Pédiatrie > Service néonatologie (CHR)

SENTERRE, Thibault

Studzinski, Frédéric

Kessen, Catheline

Rigo, Vincent ; Université de Liège - ULiège > Département des sciences cliniques > Néonatologie

Rigo, Jacques ; Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques

Language :

English

Title :

Growth Benefits of Own Mother's Milk in Preterm Infants Fed Daily Individualized Fortified Human Milk.

Publication date :

03 April 2019

Journal title :

Nutrients

ISSN :

2072-6643

Publisher :

Multidisciplinary Digital Publishing Institute (MDPI), Switzerland

Volume :

Issue :

Pages :

E772

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

https://www.mdpi.com/2072-6643/11/4/772

Available on ORBi :

since 18 September 2019

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