HYBRID NANOFIBERS BASED ON POLY-CAPROLACTONE/GELATINHYDROXYAPATITE NANOPARTICLES-LOADED DOXYCYCLINE: EFFECTIVE ANTI-TUMORAL AND ANTIBACTERIAL ACTIVITY

Ramíres-Agudelo, Ricardo; Scheuermann, Karina; Gala-García, Alfonso; Monteiro, Ana; Pinzíon-García, Ana Delia; Cortés, Maria Esperanza; Sinisterra, Rubén Dario

doi:10.1016/j.msec.2017.08.012

Article (Scientific journals)

HYBRID NANOFIBERS BASED ON POLY-CAPROLACTONE/GELATINHYDROXYAPATITE NANOPARTICLES-LOADED DOXYCYCLINE: EFFECTIVE ANTI-TUMORAL AND ANTIBACTERIAL ACTIVITY

Ramíres-Agudelo, Ricardo; Scheuermann, Karina; Gala-García, Alfonso et al.

2018 • In Materials Science and Engineering: C: Materials for Biological Applications

Peer Reviewed verified by ORBi

Permalink
https://hdl.handle.net/2268/239222

DOI
10.1016/j.msec.2017.08.012

PubMed
29208285

Files (1)Send to Details Statistics Bibliography Similar publications

Files

Full Text

2018 - Hybrid nanofibers based on poly-caprolactone-gelatin-hydroxya patite.pdf

Publisher postprint (1.21 MB)

Request a copy

All documents in ORBi are protected by a user license.

Send to

RIS BibTex APA Chicago Permalink X Linkedin

Details

Disciplines :

Chemistry

Author, co-author :

Ramíres-Agudelo, Ricardo; Universidade Federal de Minas Gerais > Chemistry Department

Scheuermann, Karina; Universidade Federal de Minas Gerais > Chemistry Department

Gala-García, Alfonso; Universidade Federal de Minas Gerais > Restorative Dentistry Department

Monteiro, Ana ; Université de Liège - ULiège > CEIB

Pinzíon-García, Ana Delia; Universidade Federal de Minas Gerais > Chemistry Department

Cortés, Maria Esperanza; Universidade Federal de Minas Gerais > Restorative Dentistry Department

Sinisterra, Rubén Dario; Universidade Federal de Minas Gerais > Chemistry Department

Language :

English

Title :

HYBRID NANOFIBERS BASED ON POLY-CAPROLACTONE/GELATINHYDROXYAPATITE NANOPARTICLES-LOADED DOXYCYCLINE: EFFECTIVE ANTI-TUMORAL AND ANTIBACTERIAL ACTIVITY

Publication date :

2018

Journal title :

Materials Science and Engineering: C: Materials for Biological Applications

ISSN :

0928-4931

eISSN :

1873-0191

Publisher :

Elsevier, Amsterdam, Netherlands

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 06 September 2019

Statistics

Number of views

29 (2 by ULiège)

Number of downloads

0 (0 by ULiège)

More statistics

Scopus citations^®

Scopus citations^®
without self-citations

OpenCitations

OpenAlex citations

Bibliography

Steeg, P.S., Targeting metastasis. Nat. Rev. Cancer 16:4 (2016), 201–218.
Valentín, S., Morales, A., Sánchez, J.L., Rivera, A., Safety and efficacy of doxycycline in the treatment of rosacea. Clin. Cosmet. Investig. Dermatol. 2 (2009), 129–140.
Saikali, Z., Singh, G., Doxycycline and other tetracyclines in the treatment of bone metastasis. Anti-Cancer Drugs 14:10 (2003), 773–778.
Suárez, D.F., Consuegra, J., Trajano, V.C., Gontijo, S.M., Guimarães, P.P., Cortés, M.E., Denadai, Â.L., Sinisterra, R.D., Structural and thermodynamic characterization of doxycycline/β-cyclodextrin supramolecular complex and its bacterial membrane interactions. Colloids Surf. B: Biointerfaces 118 (2014), 194–201.
Garrido-Mesa, N., Zarzuelo, A., Galvez, J., Minocycline: far beyond an antibiotic. Br. J. Pharmacol. 169:2 (2013), 337–352.
Lamb, R., Ozsvari, B., Lisanti, C.L., Tanowitz, H.B., Howell, A., Martinez-Outschoorn, U.E., Sotgia, F., Lisanti, M.P., Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: treating cancer like an infectious disease. Oncotarget 6:7 (2015), 4569–4584.
Yang, B., Lu, Y., Zhang, A., Zhou, A., Zhang, L., Zhang, L., Gao, L., Zang, Y., Tang, X., Sun, L., Doxycycline induces apoptosis and inhibits proliferation and invasion of human cervical carcinoma stem cells. PLoS One, 10(6), 2015, e0129138.
Roy, R., Yang, J., Moses, M.A., Matrix metalloproteinases as novel biomarker s and potential therapeutic targets in human cancer. J. Clin. Oncol. 27:31 (2009), 5287–5297.
Hidalgo, M., Eckhardt, S.G., Development of matrix metalloproteinase inhibitors in cancer therapy. J. Natl. Cancer Inst. 93:3 (2001), 178–193.
Dey, S., Das, M., Balla, V.K., Effect of hydroxyapatite particle size, morphology and crystallinity on proliferation of colon cancer HCT116 cells. Mater. Sci. Eng. C 39 (2014), 336–339.
Shen, L.-C., Chen, Y.-K., Lin, L.-M., Shaw, S.-Y., Anti-invasion and anti-tumor growth effect of doxycycline treatment for human oral squamous-cell carcinoma–in vitro and in vivo studies. Oral Oncol. 46:3 (2010), 178–184.
Cui, X., Liang, T., Liu, C., Yuan, Y., Qian, J., Correlation of particle properties with cytotoxicity and cellular uptake of hydroxyapatite nanoparticles in human gastric cancer cells. Mater. Sci. Eng. C 67 (2016), 453–460.
Li, B., Guo, B., Fan, H., Zhang, X., Preparation of nano-hydroxyapatite particles with different morphology and their response to highly malignant melanoma cells in vitro. Appl. Surf. Sci. 255:2 (2008), 357–360.
Wolinsky, J.B., Colson, Y.L., Grinstaff, M.W., Local drug delivery strategies for cancer treatment: gels, nanoparticles, polymeric films, rods, and wafers. J. Control. Release 159:1 (2012), 14–26.
Kai, D., Jiang, S., Low, Z.W., Loh, X.J., Engineering highly stretchable lignin-based electrospun nanofibers for potential biomedical applications. J. Mater. Chem. B 3:30 (2015), 6194–6204.
Monteiro, A.P.F., Rocha, C.M.S.L., Oliveira, M.F., Gontijo, S.M.L., Agudelo, R.R., Sinisterra, R.D., Cortés, M.E., Nanofibers containing tetracycline/β-cyclodextrin: physico-chemical characterization and antimicrobial evaluation. Carbohydr. Polym. 156 (2017), 417–426.
Vasita, R., Katti, D.S., Nanofibers and their applications in tissue engineering. Int. J. Nanomedicine, 1(1), 2006, 15.
Kai, D., Liow, S.S., Loh, X.J., Biodegradable polymers for electrospinning: towards biomedical applications. Mater. Sci. Eng. C Mater. Biol. Appl. 45 (2014), 659–670.
Kai, D., Ren, W., Tian, L.L., Chee, P.L., Liu, Y., Ramakrishna, S., Loh, X.J., Engineering poly(lactide)-lignin nanofibers with antioxidant activity for biomedical application. ACS Sustain. Chem. Eng. 4:10 (2016), 5268–5276.
Sell, S.A., Wolfe, P.S., Garg, K., McCool, J.M., Rodriguez, I.A., Bowlin, G.L., The use of natural polymers in tissue engineering: a focus on electrospun extracellular matrix analogues. Polymer 2:4 (2010), 522–553.
Zheng, F., Wang, S., Shen, M., Zhu, M., Shi, X., Antitumor efficacy of doxorubicin-loaded electrospun nano-hydroxyapatite–poly (lactic-co-glycolic acid) composite nanofibers. Polym. Chem. 4:4 (2013), 933–941.
Spearman, S.S., Rivero, I.V., Abidi, N., Influence of polycaprolactone/polyglycolide blended electrospun fibers on the morphology and mechanical properties of polycaprolactone. J. Appl. Polym. Sci., 131(9), 2014.
Kai, D., Prabhakaran, M.P., Chan, B.Q.Y., Liow, S.S., Ramakrishna, S., Xu, F.J., Loh, X.J., Elastic poly(epsilon-caprolactone)-polydimethylsiloxane copolymer fibers with shape memory effect for bone tissue engineering. Biomed. Mater., 11(1), 2016.
Lakshminarayanan, R., Sridhar, R., Loh, X.J., Nandhakumar, M., Barathi, V.A., Kalaipriya, M., Kwan, J.L., Liu, S.P., Beuerman, R.W., Ramakrishna, S., Interaction of gelatin with polyenes modulates antifungal activity and biocompatibility of electrospun fiber mats. Int. J. Nanomedicine 9 (2014), 2439–2458.
Chong, E., Phan, T., Lim, I., Zhang, Y., Bay, B., Ramakrishna, S., Lim, C., Evaluation of electrospun PCL/gelatin nanofibrous scaffold for wound healing and layered dermal reconstitution. Acta Biomater. 3:3 (2007), 321–330.
Ghasemi-Mobarakeh, L., Prabhakaran, M.P., Morshed, M., Nasr-Esfahani, M.-H., Ramakrishna, S., Electrospun poly (ɛ-caprolactone)/gelatin nanofibrous scaffolds for nerve tissue engineering. Biomaterials 29:34 (2008), 4532–4539.
Alvarez-Perez, M.A., Guarino, V., Cirillo, V., Ambrosio, L., Influence of gelatin cues in PCL electrospun membranes on nerve outgrowth. Biomacromolecules 11:9 (2010), 2238–2246.
Feng, B., Duan, H., Fu, W., Cao, Y., Jie Zhang, W., Zhang, Y., Effect of inhomogeneity of the electrospun fibrous scaffolds of gelatin/polycaprolactone hybrid on cell proliferation. J. Biomed. Mater. Res. A 103:2 (2015), 431–438.
Kim, M.S., Jun, I., Shin, Y.M., Jang, W., Kim, S.I., Shin, H., The development of genipin-crosslinked poly (caprolactone) (PCL)/gelatin nanofibers for tissue engineering applications. Macromol. Biosci. 10:1 (2010), 91–100.
Ramier, J., Bouderlique, T., Stoilova, O., Manolova, N., Rashkov, I., Langlois, V., Renard, E., Albanese, P., Grande, D., Biocomposite scaffolds based on electrospun poly (3-hydroxybutyrate) nanofibers and electrosprayed hydroxyapatite nanoparticles for bone tissue engineering applications. Mater. Sci. Eng. C 38 (2014), 161–169.
Yoo, H.S., Kim, T.G., Park, T.G., Surface-functionalized electrospun nanofibers for tissue engineering and drug delivery. Adv. Drug Deliv. Rev. 61:12 (2009), 1033–1042.
Kai, D., Tan, M.J., Prabhakaran, M.P., Chan, B.Q.Y., Liow, S.S., Ramakrishna, S., Loh, X.J., Biocompatible electrically conductive nanofibers from inorganic-organic shape memory polymers. Colloids Surf. B Biointerfaces 148 (2016), 557–565.
Hu, J., Kai, D., Ye, H.Y., Tian, L.L., Ding, X., Ramakrishna, S., Loh, X.J., Electrospinning of poly(glycerol sebacate)-based nanofibers for nerve tissue engineering. Mater. Sci. Eng. C Mater. Biol. Appl. 70 (2017), 1089–1094.
Loh, X.J., Peh, P., Liao, S., Sng, C., Li, J., Controlled drug release from biodegradable thermoresponsive physical hydrogel nanofibers. J. Control. Release 143:2 (2010), 175–182.
Zhao, Y.F., Ma, J., Triblock co-polymer templating synthesis of mesostructured hydroxyapatite. Microporous Mesoporous Mater. 87:2 (2005), 110–117.
Binulal, N.S., Natarajan, A., Menon, D., Bhaskaran, V.K., Mony, U., Nair, S.V., PCL-gelatin composite nanofibers electrospun using diluted acetic acid-ethyl acetate solvent system for stem cell-based bone tissue engineering. J. Biomater. Sci. Polym. Ed. 25:4 (2014), 325–340.
Kim, K., Luu, Y.K., Chang, C., Fang, D., Hsiao, B.S., Chu, B., Hadjiargyrou, M., Incorporation and controlled release of a hydrophilic antibiotic using poly (lactide-co-glycolide)-based electrospun nanofibrous scaffolds. J. Control. Release 98:1 (2004), 47–56.
Zhou, H., Lee, J., Nanoscale hydroxyapatite particles for bone tissue engineering. Acta Biomater. 7:7 (2011), 2769–2781.
Wang, S., Wang, X., Xu, H., Abe, H., Tan, Z., Zhao, Y., Guo, J., Naito, M., Ichikawa, H., Fukumori, Y., Towards sustained delivery of small molecular drugs using hydroxyapatite microspheres as the vehicle. Adv. Powder Technol. 21:3 (2010), 268–272.
Boonsongrit, Y., Abe, H., Sato, K., Naito, M., Yoshimura, M., Ichikawa, H., Fukumori, Y., Controlled release of bovine serum albumin from hydroxyapatite microspheres for protein delivery system. Mater. Sci. Eng. B 148:1–3 (2008), 162–165.
Wang, A., Liu, D., Yin, H., Wu, H., Wada, Y., Ren, M., Jiang, T., Cheng, X., Xu, Y., Size-controlled synthesis of hydroxyapatite nanorods by chemical precipitation in the presence of organic modifiers. Mater. Sci. Eng. C 27:4 (2007), 865–869.
Puvvada, N., Panigrahi, P.K., Pathak, A., Room temperature synthesis of highly hemocompatible hydroxyapatite, study of their physical properties and spectroscopic correlation of particle size. Nano 2:12 (2010), 2631–2638.
Kruk, M., Jaroniec, M., Gas adsorption characterization of ordered organic–inorganic nanocomposite materials. Chem. Mater. 13:10 (2001), 3169–3183.
Pham, Q.P., Sharma, U., Mikos, A.G., Electrospinning of polymeric nanofibers for tissue engineering applications: a review. Tissue Eng. 12:5 (2006), 1197–1211.
Meng, Z.X., Xu, X.X., Zheng, W., Zhou, H.M., Li, L., Zheng, Y.F., Lou, X., Preparation and characterization of electrospun PLGA/gelatin nanofibers as a potential drug delivery system. Colloids Surf. B: Biointerfaces 84:1 (2011), 97–102.
Kołbuk, D., Sajkiewicz, P., Maniura-Weber, K., Fortunato, G., Structure and morphology of electrospun polycaprolactone/gelatine nanofibres. Eur. Polym. J. 49:8 (2013), 2052–2061.
Yang, X., Yang, F., Walboomers, X.F., Bian, Z., Fan, M., Jansen, J.A., The performance of dental pulp stem cells on nanofibrous PCL/gelatin/nHA scaffolds. J. Biomed. Mater. Res. A 93:1 (2010), 247–257.
Binulal, N., Deepthy, M., Selvamurugan, N., Shalumon, K., Suja, S., Mony, U., Jayakumar, R., Nair, S., Role of nanofibrous poly (caprolactone) scaffolds in human mesenchymal stem cell attachment and spreading for in vitro bone tissue engineering—response to osteogenic regulators. Tissue Eng. A 16:2 (2010), 393–404.
Elzein, T., Nasser-Eddine, M., Delaite, C., Bistac, S., Dumas, P., FTIR study of polycaprolactone chain organization at interfaces. J. Colloid Interface Sci. 273:2 (2004), 381–387.
Ki, C.S., Baek, D.H., Gang, K.D., Lee, K.H., Um, I.C., Park, Y.H., Characterization of gelatin nanofiber prepared from gelatin–formic acid solution. Polymer 46:14 (2005), 5094–5102.
Shi, R., Xue, J., Wang, H., Wang, R., Gong, M., Chen, D., Zhang, L., Tian, W., Fabrication and evaluation of a homogeneous electrospun PCL-gelatin hybrid membrane as an anti-adhesion barrier for craniectomy. J. Mater. Chem. B 3:19 (2015), 4063–4073.
Sangeetha, K., Kalkura, S., Yokogawa, Y., Thamizhavel, A., Girija, E., Novel porogen free porous hydroxyapatite–gelatin nanocomposite: synthesis and characterization. Advanced Nanomaterials and Nanotechnology, 2013, Springer, 399–407.
Chang, M.C., Organic–inorganic interaction between hydroxyapatite and gelatin with the aging of gelatin in aqueous phosphoric acid solution. J. Mater. Sci. Mater. Med. 19:11 (2008), 3411–3418.
Wang, S., Guo, S., Cheng, L., Disodium norcantharidate loaded poly (ɛ-caprolactone) microspheres: I. Preparation and evaluation. Int. J. Pharm. 350:1 (2008), 130–137.
Rivero, S., García, M., Pinotti, A., Correlations between structural, barrier, thermal and mechanical properties of plasticized gelatin films. Innovative Food Sci. Emerg. Technol. 11:2 (2010), 369–375.
Biscarat, J., Bechelany, M., Pochat-Bohatier, C., Miele, P., Graphene-like BN/gelatin nanobiocomposites for gas barrier applications. Nano 7:2 (2015), 613–618.
Gautam, S., Dinda, A.K., Mishra, N.C., Fabrication and characterization of PCL/gelatin composite nanofibrous scaffold for tissue engineering applications by electrospinning method. Mater. Sci. Eng. C 33:3 (2013), 1228–1235.
Mohamed, A., Finkenstadt, V.L., Gordon, S.H., Biresaw, G., Palmquist, D.E., Rayas-Duarte, P., Thermal properties of PCL/gluten bioblends characterized by TGA, DSC, SEM, and infrared-PAS. J. Appl. Polym. Sci. 110:5 (2008), 3256–3266.
Wan, Y., Zuo, G., Liu, C., Li, X., He, F., Ren, K., Luo, H., Preparation and characterization of nano-platelet-like hydroxyapatite/gelatin nanocomposites. Polym. Adv. Technol. 22:12 (2011), 2659–2664.
Tortora, G., Funke, R.B., Case, L.C., Microbiology: An Introduction. 2001, Addison-Wesley Longman, Inc., New York.
Carlson, G.A., Dragoo, J.L., Samimi, B., Bruckner, D.A., Bernard, G.W., Hedrick, M., Benhaim, P., Bacteriostatic properties of biomatrices against common orthopaedic pathogens. Biochem. Biophys. Res. Commun. 321:2 (2004), 472–478.
Ueshima, M., Tanaka, S., Nakamura, S., Yamashita, K., Manipulation of bacterial adhesion and proliferation by surface charges of electrically polarized hydroxyapatite. J. Biomed. Mater. Res. 60:4 (2002), 578–584.
Liu, S., Zhou, G., Liu, D., Xie, Z., Huang, Y., Wang, X., Wu, W., Jing, X., Inhibition of orthotopic secondary hepatic carcinoma in mice by doxorubicin-loaded electrospun polylactide nanofibers. J. Mater. Chem. B 1:1 (2013), 101–109.
Hu, X., Liu, S., Zhou, G., Huang, Y., Xie, Z., Jing, X., Electrospinning of polymeric nanofibers for drug delivery applications. J. Control. Release 185:0 (2014), 12–21.
Vallath, S., Sage, E.K., Kolluri, K.K., Lourenco, S.N., Teixeira, V.S., Chimalapati, S., George, P.J., Janes, S.M., Giangreco, A., CADM1 inhibits squamous cell carcinoma progression by reducing STAT3 activity. Sci Rep, 6, 2016.
Wang, H., Zhao, Y., Wu, Y., Hu, Y.-l., Nan, K., Nie, G., Chen, H., Enhanced anti-tumor efficacy by co-delivery of doxorubicin and paclitaxel with amphiphilic methoxy PEG-PLGA copolymer nanoparticles. Biomaterials 32:32 (2011), 8281–8290.
Xu, J., Xu, P., Li, Z., Huang, J., Yang, Z., Oxidative stress and apoptosis induced by hydroxyapatite nanoparticles in C6 cells. J. Biomed. Mater. Res. A 100:3 (2012), 738–745.
Leinonen, T., Pirinen, R., Bohm, J., Johansson, R., Kosma, V.M., Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer. Histol. Histopathol. 23:6 (2008), 693–700.
Passlick, B., Sienel, W., Seen-Hibler, R., Wöckel, W., Thetter, O., Mutschler, W., Pantel, K., Overexpression of matrix metalloproteinase 2 predicts unfavorable outcome in early-stage non-small cell lung cancer. Clin. Cancer Res. 6:10 (2000), 3944–3948.