Relationship between peak expiratory flow and incidence of frailty, deaths and falls among nursing home residents: Results of the SENIOR cohort

Charles, Alexia; Buckinx, Fanny; Cataldo, Didier; Rygaert, X.; Gruslin, B.; Reginster, Jean-Yves; Bruyère, Olivier

doi:10.1016/j.archger.2019.103913

Article (Scientific journals)

Relationship between peak expiratory flow and incidence of frailty, deaths and falls among nursing home residents: Results of the SENIOR cohort

Charles, Alexia; Buckinx, Fanny; Cataldo, Didier et al.

2019 • In Archives of Gerontology and Geriatrics, 85

Peer Reviewed verified by ORBi

Permalink
https://hdl.handle.net/2268/238613

DOI
10.1016/j.archger.2019.103913

PubMed
31357107

Files (1)Send to Details Statistics Bibliography Similar publications

Files

Full Text

Relationship between peak expiratory flow and incidence of frailty, deaths and falls among nursing home residents - results of the SENIOR cohort.pdf

Publisher postprint (278.73 kB)

Request a copy

All documents in ORBi are protected by a user license.

Send to

RIS BibTex APA Chicago Permalink X Linkedin

Details

Keywords :

Adverse outcomes; Frailty; Institutionalization; Respiratory function

Abstract :

[en] Objective: To correlate peak expiratory flow (PEF) with the incidence of frailty, deaths and falls among nursing home residents. Methods: This is a 1-year longitudinal analysis performed on the clinical data of the SENIOR cohort. PEF, measured by peak flow meter, was considered as “low” when the observed value was ≤80% of the theoretical value. Physical capacity was evaluated using Short Physical Performance Battery, balance and gait using Tinetti test and muscle strength using a dynamometer. The incidence of frailty was defined as the transition from a “robust” or “prefrail” status to a “frail” status following Fried's criteria. Deaths and falls were also collected. Results: Among 646 subjects included at baseline (83.2 ± 9 years and 72.1% women), 297 (45.7%) displayed a low PEF. In this subgroup, physical capacity (p-values from 0.01 to <0.001), muscle strength (p < 0.001), balance and gait score (p < 0.001) were significantly lower compared to subjects displaying normal PEF. Subjects who became frail after one year displayed a lower % of the theoretical PEF value compared to those that did not (88.52 ± 45.06 vs 102.78 ± 50.29, respectively, p = 0.03). After adjustment for potential confounding variables (calf circumference, Tinetti test, SPPB test and handgrip strength), PEF was no longer associated with the occurrence of frailty. There was no association between PEF and mortality and falls. Conclusion: In a nursing home setting, PEF is not an independent factor associated with the incidence of frailty, deaths and falls. © 2019 Elsevier B.V.

Disciplines :

Public health, health care sciences & services

Author, co-author :

Charles, Alexia ; Université de Liège - ULiège > Département des sciences de la santé publique > Epidémiologie clinique

Buckinx, Fanny ; Université de Liège - ULiège > Département des sciences de la santé publique > Département des sciences de la santé publique

Cataldo, Didier ; Université de Liège - ULiège > Département des sciences cliniques > Labo de biologie des tumeurs et du développement

Rygaert, X.; Department of Public Health, Epidemiology and Health Economics, University of Liège, WHO Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Ageing, Avenue Hippocrate 13, Liège, Belgium

Gruslin, B.; Department of Public Health, Epidemiology and Health Economics, University of Liège, WHO Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Ageing, Avenue Hippocrate 13, Liège, Belgium

Reginster, Jean-Yves ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé

Bruyère, Olivier ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé

Language :

English

Title :

Relationship between peak expiratory flow and incidence of frailty, deaths and falls among nursing home residents: Results of the SENIOR cohort

Publication date :

2019

Journal title :

Archives of Gerontology and Geriatrics

ISSN :

0167-4943

eISSN :

1872-6976

Publisher :

Elsevier Ireland Ltd

Volume :

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 13 August 2019

Statistics

Number of views

76 (14 by ULiège)

Number of downloads

5 (2 by ULiège)

More statistics

Scopus citations^®

Scopus citations^®
without self-citations

OpenCitations

OpenAlex citations

Bibliography

Albert, M.S., Jones, K., Savage, C.R., Berkman, L., Seeman, T., Blazer, D., et al. Predictors of cognitive change in older persons: MacArthur studies of successful aging. Psychology and Aging 10:4 (1995), 578–589.
Bellia, V., Pistelli, R., Catalano, F., Antonelli-Incalzi, R., Grassi, V., Melillo, G., et al. Quality control of spirometry in the elderly. American Journal of Respiratory and Critical Care Medicine 161 (2000), 1094–1100, 10.1164/ajrccm.161.4.9810093.
Bellia, V., Pistelli, F., Giannini, D., Scichilone, N., Catalano, F., Spatafora, M., et al. Questionnaires, spirometry and PEF monitoring in epidemiological studies on elderly respiratory patients. The European Respiratory Journal 21:Supplement 40 (2003), 21S–27s, 10.1183/09031936.03.00402303.
Bone, A.E., Hepgul, N., Kon, S., Maddocks, M., Sarcopenia and frailty in chronic respiratory disease: Lessons from gerontology. Chronic Respiratory Disease 14:1 (2017), 85–99, 10.1177/1479972316679664.
Buckinx, F., Rolland, Y., Reginster, J.Y., Ricour, C., Petermans, J., Bruyère, O., Burden of frailty in the elderly population: Perspectives for a public health challenge. Archives of Public Health 73:1 (2015), 1–7, 10.1186/s13690-015-0068-x.
Buckinx, F., Croisier, J.L., Reginster, J.Y., Petermans, J., Goffart, E., Bruyere, O., Relationship between isometric strength of six lower limb muscle groups and motor skills among nursing home residents. The Journal of Frailty & Aging 4:4 (2015), 184–187, 10.14283/jfa.2015.70.
Buckinx, F., Reginster, J.Y., Petermans, J., Croisier, J.L., Beaudart, C., Brunois, T., et al. Relationship between frailty, physical performance and quality of life among nursing home residents: The SENIOR cohort. Aging Clinical and Experimental Research 28:6 (2016), 1149–1157, 10.1007/s40520-016-0616-4.
Buckinx, F., Croisier, J.L., Reginster, J.Y., Lenaerts, C., Brunois, T., Rygaert, X., et al. Prediction of the incidence of falls and deaths among elderly nursing home residents: The SENIOR study. Journal of the American Medical Directors Association 19:1 (2018), 18–24, 10.1016/j.jamda.2017.06.014.
Cruz-Jentofs, A.J., Bahat, G., Bauer, J., Boirie, Y., Bruyère, O., Cederholm, T., et al. Sarcopenia: Revised European consensus on definition and diagnosis. Age and Ageing(September 2018), 2019, 16–31, 10.1093/ageing/afy169.
Dent, E., Kowal, P., Hoogendijk, E.O., Frailty measurement in research and clinical practice: A review. European Journal of Internal Medicine 31 (2016), 3–10, 10.1016/j.ejim.2016.03.007.
Fried, L.P., Tangen, C.M., Walston, J., Newman, A.B., Hirsch, C., Gottdiener, J., et al. Frailty in older adults: Evidence for a phenotype. Journal of Gerontology 56:3 (2001), 146–157.
Furtado, G., Patrício, M., Loureiro, M., Teixeira, A.M., Ferreira, J.P., Physical fitness and frailty syndrome in institutionalized older women. Perceptual and Motor Skills 124:4 (2017), 754–776, 10.1177/0031512517709915.
Gale, C.R.G., Cooper, C.C., Westbury, L.D., Dennison, E., Prevalence and risk factors for falls in older men and women: The English Longitudinal Study of Ageing. Age and Ageing, 2016, 1–6, 10.1093/ageing/afw129.
Gawel, J., Vengrow, D., Collins, J., Brown, S., Buchanan, A., Cook, C., The short physical performance battery as a predictor for long term disability or institutionalization in the community dwelling population aged 65 years old or older. The Physical Therapy Review 17:1 (2012), 37–44, 10.1179/1743288X11Y.0000000050.
Gregg, I., Nunn, A.J., Nunn, M., Peak expiratory flow in symptomless elderly smokers and ex-smokers. British Medical Journal 298:April (1989), 1071–1072.
Hansen, E.F., Vestbo, J., Phanareth, K., Kok-Jensen, A., Dirksen, A., Peak flow as predictor of overall mortality in asthma and chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine 163:3 Pt 1 (2001), 690–693, 10.1164/ajrccm.163.3.2006120.
Hegendörfer, E., Vaes, B., Andreeva, E., Matheï, C., Van Pottelbergh, G., Degryse, J.M., Predictive value of different expressions of forced expiratory volume in 1 second (FEV1) for adverse outcomes in a cohort of adults aged 80 and older. Journal of the American Medical Directors Association 18:2 (2017), 123–130, 10.1016/j.jamda.2016.08.012.
Hegewald, M.J., Lefor, M.J., Jensen, R.L., Crapo, R.O., Kritchevsky, S.B., Haggerty, C.L., et al. Peak expiratory flow is not a quality indicator for spirometry. Chest 131:5 (2007), 1494–1499, 10.1378/chest.06-2707.
Kera, T., Kawai, H., Hirano, H., Kojima, M., Fujiwara, Y., Ihara, K., et al. Relationships among peak expiratory flow rate, body composition, physical function, and sarcopenia in community-dwelling older adults. Aging Clinical and Experimental Research 30:4 (2018), 331–340, 10.1007/s40520-017-0777-9.
Lahousse, L., Ziere, G., Verlinden, V.J.A., Zillikens, M.C., Uitterlinden, A.G., Rivadeneira, F., et al. Risk of frailty in elderly with COPD: A population-based study. Journals of Gerontology Series A: Biological Sciences and Medical Sciences 71:5 (2016), 689–695, 10.1093/gerona/glv154.
Lee, W.-J., Peng, L.-N., Chiou, S.-T., Chen, L.-K., Physical health indicators improve prediction of cardiovascular and all-cause mortality among middle-aged and older people: A national population-based study. Scientific Reports, 7, 2017, 40427, 10.1038/srep40427.
Leng, S., Chen, X., Mao, G., Frailty syndrome: An overview. Clinical Interventions in Aging 9 (2014), 433–441, 10.2147/CIA.S45300.
Liu, Z., Wei, Y., Wei, L., Jiang, X., Wang, X., Shi, Y., et al. Frailty transitions and types of death in Chinese older adults: A population-based cohort study. Clinical Interventions in Aging 13 (2018), 947–956, 10.2147/CIA.S157089.
Marengoni, A., Vetrano, D.L., Manes-Gravina, E., Bernabei, R., Onder, G., Palmer, K., The relationship between chronic obstructive pulmonary disease and frailty: A systematic review and meta-analysis of observational studies. Chest 154:1 (2018), 21–40, 10.1016/j.chest.2018.02.014.
Miller, M.R., Hankinson, J., Brusasco, V., Burgos, F., Casaburi, R., Coates, A., et al. Standardisation of spirometry. The European Respiratory Journal 26:2 (2005), 319–338, 10.1183/09031936.05.00034805.
Nunn, A.J., Gregg, I., New regression equations for predicting peak expiratory flow in adults. BMJ 298:6680 (1989), 1068–1070, 10.1136/bmj.298.6680.1068.
Park, C., Yi, Y., Do, J.G., Lee, Y., Yoon, K.J., Relationship between skeletal muscle mass and lung function in Korean adults without clinically apparent lung disease. Medicine, 97(37), 2018, e12281.
Pegorari, M.S., Ruas, G., Patrizzi, L.J., Relationship between frailty and respiratory function in the community-dwelling elderly. Brazilian Journal of Physical Therapy 17:1 (2013), 9–16, 10.1590/S1413-35552012005000065.
Podsiadlo, D., Richardson, S., The timed “up & go”: A test of basic functional mobility for frail elderly persons. Journal of the American Geriatrics Society 39:2 (1991), 142–148.
Portney, L., Watkins, M., Hall, P., (eds.) Foundations of clinical research: Applications to practice, 3rd edition, 2002 Upper Saddle River.
Quanjer, P.H., Lebowitz, M.D., Gregg, I., Miller, M.R., Pedersen, O.F., Peak expiratory flow: Conclusions and recommendations of a Working Party of the European Respiratory Society. The European Respiratory Journal 10:24 (1997), 2S–8S.
Roberts, M.H., Mapel, D.W., Limited lung function: Impact of reduced peak expiratory flow on health status, health-care utilization, and expected survival in older adults. American Journal of Epidemiology 176:2 (2012), 127–134, 10.1093/aje/kwr503.
Roberts, H.C., Denison, H.J., Martin, H.J., Patel, H.P., Syddall, H., Cooper, C., et al. A review of the measurement of grip strength in clinical and epidemiological studies: Towards a standardised approach. Age and Ageing 40:4 (2011), 423–429, 10.1093/ageing/afr051.
Rockwood, K., Conceptual models of frailty: Accumulation of deficits. The Canadian Journal of Cardiology 32:9 (2016), 1046–1050, 10.1016/j.cjca.2016.03.020.
Smolej Narančić, N., Pavlović, M., Žuškin, E., Milicic, J., Skaric-Juric, T., Barbalic, M., et al. New reference equations for forced spirometry in elderly persons. Respiratory Medicine 103:4 (2009), 621–628, 10.1016/j.rmed.2008.10.013.
Société Belge de Pneumologie, Normes de qualite, indications et standardisation des épreuves fonctionnelles respiratoires: Document de consensus. 2001 Published (Accessed 12 December 2018) https://www.bvp-sbp.org/index.php/en/guidelines.
Tabue-Teguo, M., Dartigues, J.F., Simo, N., Kuate-Tegueu, C., Vellas, B., Cesari, M., Physical status and frailty index in nursing home residents: Results from the INCUR study. Archives of Gerontology and Geriatrics 74:October 2017 (2018), 72–76, 10.1016/j.archger.2017.10.005.
Tinetti, M.E., Performance‐oriented assessment of mobility problems in elderly patients. Journal of the American Geriatrics Society 34:2 (1986), 119–126, 10.1111/j.1532-5415.1986.tb05480.x.
Vaz Fragoso, C.A., Gahbauer, E.A., Van Ness, P.H., Concato, J., Gill, T.M., Peak expiratory flow as a predictor of subsequent disability and death in community-living older persons. Journal of the American Geriatrics Society 56:6 (2008), 1014–1020, 10.1111/j.1532-5415.2008.01687.x.
Vaz Fragoso, C., Gahbauer, E., Van Hess, P., Gill, Yu, T., Reporting peak expiratory flow in older persons. The Journals of Gerontology Series A, Biological Sciences and Medical Sciences 62:10 (2009), 1147–1151.
Vaz Fragoso, C.A., Enright, P.L., McAvay, G., Van Ness, P.H., Gill, T.M., Frailty and respiratory impairment in older persons. The American Journal of Medicine 125:1 (2012), 79–86, 10.1016/j.amjmed.2011.06.024.
Weiss, C.O., Hoenig, H.H., Varadhan, R., Simonsick, E.M., Fried, L.P., Relationships of cardiac, pulmonary, and muscle reserves and frailty to exercise capacity in older women. Journals of Gerontology Series A: Biological Sciences and Medical Sciences 65 A:3 (2010), 287–294, 10.1093/gerona/glp147.
Xie, B., Larson, J.L., Gonzalez, R., Pressler, S.J., Lustig, C., Arslanian-Engoren, C., Components and indicators of frailty measures: A literature review. The Journal of Frailty & Aging 6:2 (2017), 76–82, 10.14283/jfa.2017.11.