Compact plasmonic multichannel spectroscopic sensor platform

we present a hybrid plasmonic sensor architecture, as well as its first experimental proof-of-concept demonstrating its practical feasibility. The proposed approach supports two detection formats on the same lab-on-chip device: surface plasmon resonance (SPR) and localized surface plasmon resonance (LSPR) biosensing. The developed instrumental platform is dedicated to multichannel microfluidic biosensing and a specific microfabrication technique involving gold nanoparticles synthesis by pulsed laser writing was developed for the LSPR part. We experimentally demonstrate that the use of the total internal spectroscopic reflectometry can significantly enhance the LSPR sensor sensitivity to refractive index variations of the liquid sample