Article (Scientific journals)
Endorsement by Central European experts of the revised ESCEO algorithm for the management of knee osteoarthritis
Kucharz, E. J.; Szántó, S.; Ivanova Goycheva, M. et al.
2019In Rheumatology International, 39, p. 1117-1123
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Keywords :
NSAID; Osteoarthritis; Paracetamol; Safety; SYSADOA
Abstract :
[en] Osteoarthritis (OA) is characterized by deterioration of the joints and associated with considerable pain and disability. OA is a chronic disease that requires intervention with both non-pharmacological and pharmacological treatment modalities and, inevitably, disease progression may necessitate successive treatments throughout the course of the disease. There is increasing data on the shortfalls of current pharmacological treatment of OA, and safety concerns associated with analgesic therapy use in OA arising from increasing evidence of gastrointestinal, cardiovascular, hepatic and renal adverse events with paracetamol and non-steroidal anti-inflammatory drugs (NSAIDs). Consequently, symptomatic slow-acting drugs for OA (SYSADOAs) may now be considered as a first-line treatment for knee OA, with a particular emphasis placed on the outstanding benefit: risk ratio of pharmaceutical-grade glucosamine and chondroitin sulfate formulations. In this short communication we review recent publications concerned with the safety of paracetamol, NSAIDs and SYSADOAs. Greater understanding of the benefits and limitations of current medications will lead to better disease management in OA. Furthermore, adherence to guideline recommendations across Europe and internationally, such as those from the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), will promote evidence-based medicine and patient-centric care, ultimately leading to greater physician and patient satisfaction. © 2019, The Author(s).
Disciplines :
General & internal medicine
Author, co-author :
Kucharz, E. J.;  Department of Internal Medicine, Rheumatology and Clinical Immunology, Medical University of Silesia, Katowice, Poland
Szántó, S.;  Department of Sports Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
Ivanova Goycheva, M.;  Rheumatology Clinic, Medical Faculty, University Hospital “St. Iv. Rilski”, Medical University, Sofia, Bulgaria
Petronijević, M.;  Clinic of Rheumatology, MMA Medical Faculty, University of Defence, Military Medical Academy, Belgrade, Serbia
Šimnovec, K.;  Department of Orthopedics, General Hospital Jesenice, Jesenice, Slovenia
Domżalski, M.;  Orthopedic and Trauma Department Medical, Veteran’s Memorial Hospital, University of Lodz, Lodz, Poland
Gallelli, L.;  Clinical Pharmacology and Pharmacovigilance Operative Unit, Department of Health Sciences, MaterDomini Hospital Catanzaro, University of Magna Graecia Catanzaro, Catanzaro, Italy
Kamenov, Z.;  Department of Internal Medicine, Clinic of Endocrinology, Medical University Sofia, University Hospital “Alexandrovska”, Sofia, Bulgaria
Konstantynowicz, J.;  Department of Pediatric Rheumatology, Immunology, and Metabolic Bone Diseases, Medical University of Bialystok, Bialystok, Poland
Radunović, G.;  Institute of Rheumatology, University of Belgrade Medical School, Resavska 69, Belgrade, Serbia
Šteňo, B.;  II. Department of Orthopaedic and Trauma Surgery, Faculty of Medicine in Bratislava, Comenius University, University Hospital Bratislava, Bratislava, Slovakia
Stoilov, R.;  Rheumatology Clinic, Medical Faculty, University Hospital “St. Iv. Rilski”, Medical University, Sofia, Bulgaria
Stok, R.;  Ultramedica, Vošnjakova 1, Ljubljana, Slovenia
Vrana, R.;  Osteocentrum Mediekos Ltd., Orthopedics, Ortopedie Hradiště Ltd., Uherské Hradiště, Czech Republic
Bruyère, Olivier  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Cooper, Cyrus
Reginster, Jean-Yves  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
More authors (7 more) Less
Language :
English
Title :
Endorsement by Central European experts of the revised ESCEO algorithm for the management of knee osteoarthritis
Publication date :
2019
Journal title :
Rheumatology International
ISSN :
0172-8172
eISSN :
1437-160X
Publisher :
Springer Verlag
Volume :
39
Pages :
1117-1123
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 18 June 2019

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