Low field magnetic resonance imaging of the equine distal interphalangeal joint: comparison between weight-bearing conditions

Evrard, Laurence; Audigié, Fabrice; Bertoni, Lélia; Jacquet, Sandrine; Denoix, Jean-Marie; Busoni, Valeria

doi:10.1371/journal.pone.0211101

Article (Scientific journals)

Low field magnetic resonance imaging of the equine distal interphalangeal joint: comparison between weight-bearing conditions

Evrard, Laurence; Audigié, Fabrice; Bertoni, Lélia et al.

2019 • In PLoS ONE

Peer Reviewed verified by ORBi

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https://hdl.handle.net/2268/236895

DOI
10.1371/journal.pone.0211101

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30689659

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Abstract :

[en] This descriptive study aimed to compare the magnetic resonance appearance of the distal interphalangeal joint articular cartilage between standing weight-bearing and non-weightbearing conditions. Ten forefeet of live horses were scanned in a standing low-field magnetic resonance system (0.27 T). After euthanasia for reasons unrelated to the study, the non-weight-bearing isolated feet were scanned in a vertical positioning reproducing limb orientation in live horses. The same acquisition settings as during the weight-bearing examination were used. Thickness and cross-sectional area of the distal interphalangeal articular cartilage and joint space were measured on tridimensional T1-weighted gradient echo high resolution frontal and sagittal images at predetermined landmarks in both conditions and were compared using a linear mixed-effects model. Frontal images were randomized and submitted to 9 blinded readers with 3 different experience levels for identification of weightbearing versus non-weight-bearing acquisitions based on cartilage appearance. Weightbearing limbs had significantly thinner distal interphalangeal cartilage (p = 0.0001) than nonweight-bearing limbs. This change was greater in the distal phalanx cartilage than that of the middle phalanx. Blinded readers correctly identified 83% (range 65 to 95%) of the images as weight-bearing or non-weight-bearing acquisitions, with significantly different results observed among the different readers (p < 0.001) and groups (p < 0.001). These results indicate that distal interphalangeal articular cartilage and particularly cartilage of the distal phalanx thins when weight-bearing compared to the non-weight-bearing standing postmortem conditions and suggest that cartilage abnormalities may be more difficult to identify on weight-bearing standing magnetic resonance imaging.

Disciplines :

Veterinary medicine & animal health

Author, co-author :

Evrard, Laurence ; Université de Liège - ULiège > Clinique vétérinaire universitaire (CVU)

Audigié, Fabrice

Bertoni, Lélia

Jacquet, Sandrine

Denoix, Jean-Marie

Busoni, Valeria ; Université de Liège - ULiège > Dép. clinique des animaux de compagnie et des équidés (DCA) > Imagerie médicale

Language :

English

Title :

Low field magnetic resonance imaging of the equine distal interphalangeal joint: comparison between weight-bearing conditions

Publication date :

28 January 2019

Journal title :

PLoS ONE

eISSN :

1932-6203

Publisher :

Public Library of Science, United States - California

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 16 June 2019

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