Veronese, N.; National Research Council, Neuroscience Institute, Aging Branch, Via Giustiniani, 2, Padua, 35128, Italy
Punzi, L.; Rheumatology Unit, Department of Medicine (DIMED), University of Padova, Padua, Italy
Sieber, C.; Institute for Biomedicine of Aging, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nuremberg, Germany, Krankenhaus Barmherzige Brüder Regensburg, Regensburg, Germany
Bauer, J.; Center for Geriatric Medicine, Agaplesion Bethanien Krankenhaus Heidelberg, University of Heidelberg, Heidelberg, Germany
Reginster, Jean-Yves ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Maggi, S.; National Research Council, Neuroscience Institute, Aging Branch, Via Giustiniani, 2, Padua, 35128, Italy
On behalf of theTask Finish Group on Arthritis of the European Geriatric Medicine Society
Language :
English
Title :
Sarcopenic osteoarthritis: a new entity in geriatric medicine?
Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F et al (2010) Sarcopenia: European consensus on definition and diagnosis: report of the European working group on sarcopenia in older people. Age Ageing 39(4):412–423. https://doi.org/10.1093/ageing/afq034
Marzetti E, Calvani R, Tosato M, Cesari M, Di Bari M, Cherubini A et al (2017) Sarcopenia: an overview. Aging Clin Exp Res 29(1):11–17. https://doi.org/10.1007/s40520-016-0704-5
Tosato M, Marzetti E, Cesari M, Savera G, Miller RR, Bernabei R et al (2017) Measurement of muscle mass in sarcopenia: from imaging to biochemical markers. Aging Clin Exp Res 29(1):19–27. https://doi.org/10.1007/s40520-016-0717-0
Bernabei R, Mariotti L, Bordes P, Roubenoff R (2017) The, “sarcopenia and physical frailty in older people: multi-component treatment strategies” (SPRINTT) project: advancing the care of physically frail and sarcopenic older people. Aging Clin Exp Res 29(1):1–2. https://doi.org/10.1007/s40520-016-0707-2
Shafiee G, Keshtkar A, Soltani A, Ahadi Z, Larijani B, Heshmat R (2017) Prevalence of sarcopenia in the world: a systematic review and meta- analysis of general population studies. J Diabetes Metab Disord 16:21. https://doi.org/10.1186/s40200-017-0302-x
Morley JE, Anker SD, von Haehling S (2014) Prevalence, incidence, and clinical impact of sarcopenia: facts, numbers, and epidemiology—update 2014. J Cachexia 5(4):253–259. https://doi.org/10.1007/s13539-014-0161-y
Morley JE, Abbatecola AM, Argiles JM, Baracos V, Bauer J, Bhasin S et al (2011) Sarcopenia with limited mobility: an international consensus. J Am Med Dir Assoc 12(6):403–409. https://doi.org/10.1016/j.jamda.2011.04.014
Bano G, Trevisan C, Carraro S, Solmi M, Luchini C, Stubbs B et al (2017) Inflammation and sarcopenia: a systematic review and meta-analysis. Maturitas 96:10–15. https://doi.org/10.1016/j.maturitas.2016.11.006
Byeon CH, Kang KY, Kang SH, Kim HK, Bae EJ (2016) Sarcopenia is not associated with depression in Korean adults: results from the 2010–2011 Korean National Health and Nutrition Examination Survey. Korean J Fam Med 37(1):37–43. https://doi.org/10.4082/kjfm.2016.37.1.37
Thomas DR (2007) Loss of skeletal muscle mass in aging: examining the relationship of starvation, sarcopenia and cachexia. Clin Nutr 26(4):389–399. https://doi.org/10.1016/j.clnu.2007.03.008
Chang KV, Hsu TH, Wu WT, Huang KC, Han DS (2017) Is sarcopenia associated with depression? A systematic review and meta-analysis of observational studies. Age Ageing 46(5):738–746. https://doi.org/10.1093/ageing/afx094
Campins L, Camps M, Riera A, Pleguezuelos E, Yebenes JC, Serra-Prat M (2017) Oral drugs related with muscle wasting and sarcopenia. A Review. Pharmacology 99(1–2):1–8. https://doi.org/10.1159/000448247
Sirven N, Rapp T, Coretti S, Ruggeri M, Cicchetti A (2017) Preventing mobility disability in Europe: a health economics perspective from the SPRINTT study. Aging Clin Exp Res 29(1):75–79. https://doi.org/10.1007/s40520-016-0713-4
Cederholm T, Cruz-Jentoft AJ, Maggi S (2013) Sarcopenia and fragility fractures. Eur J Phys Rehabil Med 49(1):111–117
Bianchi L, Ferrucci L, Cherubini A, Maggio M, Bandinelli S, Savino E et al (2015) The predictive value of the EWGSOP definition of sarcopenia: results from the InCHIANTI study. J Gerontol Series A. https://doi.org/10.1093/gerona/glv129
Rizzoli R, Reginster JY, Arnal JF, Bautmans I, Beaudart C, Bischoff-Ferrari H et al (2013) Quality of life in sarcopenia and frailty. Calcif Tissue Int 93(2):101–120. https://doi.org/10.1007/s00223-013-9758-y
Kinds MB, Welsing PMJ, Vignon EP, Bijlsma JWJ, Viergever MA, Marijnissen ACA et al (2011) A systematic review of the association between radiographic and clinical osteoarthritis of hip and knee. Osteoarthr Cartil 19(7):768–778. https://doi.org/10.1016/j.joca.2011.01.015
Litwic A, Edwards MH, Dennison EM, Cooper C (2013) Epidemiology and burden of osteoarthritis. Br Med Bull 105(1):185–199. https://doi.org/10.1093/bmb/lds038
Castell MV, van der Pas S, Otero A, Siviero P, Dennison E, Denkinger M et al (2015) Osteoarthritis and frailty in elderly individuals across six European countries: results from the European Project on OSteoArthritis (EPOSA). BMC Musculoskelet Disord 16:359. https://doi.org/10.1186/s12891-015-0807-8
Schaap LA, Peeters GMEE, Dennison EM, Zambon S, Nikolaus T, Sanchez-Martinez M et al (2011) European Project on Osteoarthritis (EPOSA): methodological challenges in harmonization of existing data from five European population-based cohorts on aging. BMC Musculoskelet Disord 12:272. https://doi.org/10.1186/1471-2474-12-272
Veronese N, Stubbs B, Noale M, Solmi M, Luchini C, Smith TO et al (2016) Adherence to a Mediterranean diet is associated with lower prevalence of osteoarthritis: data from the osteoarthritis initiative. Clin Nutr (Edinb, Scotl). https://doi.org/10.1016/j.clnu.2016.09.035
Jordan J, Luta G, Renner J, Dragomir A, Hochberg M, Fryer J (1997) Knee pain and knee osteoarthritis severity in self-reported task specific disability: the Johnston County Osteoarthritis Project. J Rheumatol 24(7):1344–1349
Veronese N, Cereda E, Maggi S, Luchini C, Solmi M, Smith T et al (2016) Osteoarthritis and mortality: a prospective cohort study and systematic review with meta-analysis. Semin Arthr Rheum 46(2):160–167. https://doi.org/10.1016/j.semarthrit.2016.04.002
Veronese N, Trevisan C, De Rui M, Bolzetta F, Maggi S, Zambon S et al (2016) Association of osteoarthritis with increased risk of cardiovascular diseases in the elderly: findings from the progetto veneto anziano study cohort. Arthr Rheumatol (Hoboken, NJ) 68(5):1136–1144. https://doi.org/10.1002/art.39564
Veronese N, Stubbs B, Solmi M, Smith TO, Reginster JY, Maggi S (2017) Osteoarthritis increases the risk of cardiovascular disease: data from the osteoarthritis initiative. J Nutr. https://doi.org/10.1007/s12603-017-0941-0
Veronese N, Stubbs B, Solmi M, Smith T, Noale M, Schofield P et al (2017) Knee osteoarthritis and risk of hypertension: a longitudinal cohort study. Rejuvenation Res. https://doi.org/10.1089/rej.2017.1917
Veronese N, Stubbs B, Solmi M, Smith TO, Noale M, Cooper C et al (2016) Association between lower limb osteoarthritis and incidence of depressive symptoms: data from the osteoarthritis initiative. Age Ageing. https://doi.org/10.1093/ageing/afw216
Stubbs B, Aluko Y, Myint PK, Smith TO (2016) Prevalence of depressive symptoms and anxiety in osteoarthritis: a systematic review and meta-analysis. Age Ageing. https://doi.org/10.1093/ageing/afw001
Huang SW, Wang WT, Chou LC, Liao CD, Liou TH, Lin HW (2015) Osteoarthritis increases the risk of dementia: a nationwide cohort study in Taiwan. Scientific Rep 5:10145. https://doi.org/10.1038/srep10145
Veronese N, Stubbs B, Noale M, Solmi M, Luchini C, Maggi S (2016) Adherence to the Mediterranean diet is associated with better quality of life: data from the osteoarthritis initiative. Am J Clin Nutr 104(5):1403–1409. https://doi.org/10.3945/ajcn.116.136390
Beaudart C, Biver E, Bruyere O, Cooper C, Al-Daghri N, Reginster JY et al (2017) Quality of life assessment in musculo-skeletal health. Aging Clin Exp Res. https://doi.org/10.1007/s40520-017-0794-8
Reginster JY, Beaudart C, Buckinx F, Bruyere O (2016) Osteoporosis and sarcopenia: two diseases or one? Curr Opin Clin Nutr Metabol Care 19(1):31–36. https://doi.org/10.1097/mco.0000000000000230
Edwards MH, van der Pas S, Denkinger MD, Parsons C, Jameson KA, Schaap L et al (2014) Relationships between physical performance and knee and hip osteoarthritis: findings from the European Project on Osteoarthritis (EPOSA). Age Ageing 43(6):806–813. https://doi.org/10.1093/ageing/afu068
Sharma L, Dunlop DD, Cahue S, Song J, Hayes KW (2003) Quadriceps strength and osteoarthritis progression in malaligned and lax knees. Ann Intern Med 138(8):613–619
Chaisson CE, Zhang Y, Sharma L, Kannel W, Felson DT (1999) Grip strength and the risk of developing radiographic hand osteoarthritis: results from the Framingham Study. Arthr Rheum 42(1):33–38. doi: 10.1002/1529-0131(199901)42:1<33::AID-ANR4>3.0.CO;2-I
Kemmler W, Teschler M, Goisser S, Bebenek M, von Stengel S, Bollheimer LC et al (2015) Prevalence of sarcopenia in Germany and the corresponding effect of osteoarthritis in females 70 years and older living in the community: results of the FORMoSA study. Clin Interven Aging 10:1565–1573. https://doi.org/10.2147/cia.s89585
Wang Y, Wluka AE, Berry PA, Siew T, Teichtahl AJ, Urquhart DM et al (2012) Increase in vastus medialis cross-sectional area is associated with reduced pain, cartilage loss, and joint replacement risk in knee osteoarthritis. Arthr Rheum 64(12):3917–3925. https://doi.org/10.1002/art.34681
De Ceuninck F, Fradin A, Pastoureau P (2014) Bearing arms against osteoarthritis and sarcopenia: when cartilage and skeletal muscle find common interest in talking together. Drug Discov Today 19(3):305–311. https://doi.org/10.1016/j.drudis.2013.08.004
Miller ME, Rejeski WJ, Messier SP, Loeser RF (2001) Modifiers of change in physical functioning in older adults with knee pain: the Observational Arthritis Study in Seniors (OASIS). Arthr Rheum 45(4):331–339. doi: 10.1002/1529-0131(200108)45:4<331::AID-ART345>3.0.CO;2-6
Scott D, Blizzard L, Fell J, Jones G (2012) Prospective study of self-reported pain, radiographic osteoarthritis, sarcopenia progression, and falls risk in community-dwelling older adults. Arthr Care Res 64(1):30–37
Isaacson J, Brotto M (2014) Physiology of mechanotransduction: how do muscle and bone “talk” to one another? Clin Rev Bone Miner Metabol 12(2):77–85. https://doi.org/10.1007/s12018-013-9152-3
Tagliaferri C, Wittrant Y, Davicco MJ, Walrand S, Coxam V (2015) Muscle and bone, two interconnected tissues. Ageing Res Rev 21:55–70. https://doi.org/10.1016/j.arr.2015.03.002
Tie K, Zhang X, Tan Y, Deng Y, Li J, Ni Q et al (2016) Intrauterine low-functional programming of IGF1 by prenatal nicotine exposure mediates the susceptibility to osteoarthritis in female adult rat offspring. FASEB J 30(2):785–797. https://doi.org/10.1096/fj.15-274399
Sassi N, Laadhar L, Allouche M, Achek A, Kallel-Sellami M, Makni S et al (2014) WNT signaling and chondrocytes: from cell fate determination to osteoarthritis physiopathology. J Recept Signal Transduc Res 34(2):73–80. https://doi.org/10.3109/10799893.2013.863919
Roman-Blas JA, Herrero-Beaumont G (2014) Targeting subchondral bone in osteoporotic osteoarthritis. Arthr Res Ther 16(6):494. https://doi.org/10.1186/s13075-014-0494-0
Cairns DM, Lee PG, Uchimura T, Seufert CR, Kwon H, Zeng L (2010) The role of muscle cells in regulating cartilage matrix production. J Orthop Res 28(4):529–536. https://doi.org/10.1002/jor.21014
Andriamanalijaona R, Duval E, Raoudi M, Lecourt S, Vilquin JT, Marolleau JP et al (2008) Differentiation potential of human muscle-derived cells towards chondrogenic phenotype in alginate beads culture. Osteoarthr Cartil 16(12):1509–1518. https://doi.org/10.1016/j.joca.2008.04.018
Stenholm S, Harris TB, Rantanen T, Visser M, Kritchevsky SB, Ferrucci L (2008) Sarcopenic obesity - definition, etiology and consequences. Curr Opin Clin Nutr Metabol Care 11(6):693–700. https://doi.org/10.1097/MCO.0b013e328312c37d
Franceschi C, Campisi J (2014) Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. J Gerontol Series A 69(Suppl 1):S4–S9. https://doi.org/10.1093/gerona/glu057
Ilich JZ, Kelly OJ, Inglis JE (2016) Osteosarcopenic obesity syndrome: what is it and how can it be identified and diagnosed? Curr Gerontol Geriatr Res 2016:7325973. https://doi.org/10.1155/2016/7325973
Lee S, Kim TN, Kim SH (2012) Sarcopenic obesity is more closely associated with knee osteoarthritis than is nonsarcopenic obesity: a cross-sectional study. Arthr Rheum 64(12):3947–3954. https://doi.org/10.1002/art.37696
Vlietstra L, Meredith-Jones K, Stebbings S, Abbott JH, Treharne GJ, Waters DL (2017) Sarcopenic obesity is more prevalent in osteoarthritis than rheumatoid arthritis: are different processes involved? Rheumatol (Oxf, Engl) 56(10):1816–1818. https://doi.org/10.1093/rheumatology/kex303
Curtis GL, Chughtai M, Khlopas A, Newman JM, Khan R, Shaffiy S et al (2017) Impact of physical activity in cardiovascular and musculoskeletal health: can motion be medicine? J Clin Med Res 9(5):375–381. https://doi.org/10.14740/jocmr3001w
Marzetti E, Calvani R, Tosato M, Cesari M, Di Bari M, Cherubini A et al (2017) Physical activity and exercise as countermeasures to physical frailty and sarcopenia. Aging Clin Exp Res 29(1):35–42. https://doi.org/10.1007/s40520-016-0705-4
Beaudart C, Dawson A, Shaw SC, Harvey NC, Kanis JA, Binkley N et al (2017) Nutrition and physical activity in the prevention and treatment of sarcopenia: systematic review. Osteoporos Int. https://doi.org/10.1007/s00198-017-3980-9
Landi F, Cesari M, Calvani R, Cherubini A, Di Bari M, Bejuit R et al (2017) The “sarcopenia and physical frailty in older people: multi-componenT Treatment strategies” (SPRINTT) randomized controlled trial: design and methods. Aging Clin Exp Res 29(1):89–100. https://doi.org/10.1007/s40520-016-0715-2
Bartels EM, Juhl CB, Christensen R, Hagen KB, Danneskiold-Samsoe B, Dagfinrud H et al (2016) Aquatic exercise for the treatment of knee and hip osteoarthritis. Cochrane Database Syst Rev 3:CD005523. https://doi.org/10.1002/14651858.CD005523.pub3
Brosseau L, Taki J, Desjardins B, Thevenot O, Fransen M, Wells GA et al (2017) The Ottawa panel clinical practice guidelines for the management of knee osteoarthritis. Part three: aerobic exercise programs. Clin Rehabil 31(5):612–624. https://doi.org/10.1177/0269215517691085
Minshull C, Gleeson N (2017) Considerations of the principles of resistance training in exercise studies for the management of knee osteoarthritis: a systematic review. Arch Phys Med Rehabil. https://doi.org/10.1016/j.apmr.2017.02.026
Osteras N, Kjeken I, Smedslund G, Moe RH, Slatkowsky-Christensen B, Uhlig T et al (2017) Exercise for hand osteoarthritis. Cochrane Database Syst Rev 1:CD010388. https://doi.org/10.1002/14651858.CD010388.pub2
Cruz-Jentoft AJ, Kiesswetter E, Drey M, Sieber CC (2017) Nutrition, frailty, and sarcopenia. Aging Clin Exp Res 29(1):43–48. https://doi.org/10.1007/s40520-016-0709-0
Bliddal H, Leeds AR, Christensen R (2014) Osteoarthritis, obesity and weight loss: evidence, hypotheses and horizons – a scoping review. Obes Rev 15(7):578–586. https://doi.org/10.1111/obr.12173
Dyer J, Davison G, Marcora SM, Mauger AR (2017) Effect of a Mediterranean type diet on inflammatory and cartilage degradation biomarkers in patients with osteoarthritis. J Nutr 21(5):562–566. https://doi.org/10.1007/s12603-016-0806-y
Hashemi R, Motlagh AD, Heshmat R, Esmaillzadeh A, Payab M, Yousefinia M et al (2016) Diet and its relationship to sarcopenia in community dwelling Iranian elderly: a cross sectional study. Nutrition 31(1):97–104. https://doi.org/10.1016/j.nut.2014.05.003
Wang Y, Hao Q, Dong B (2017) adherence to the mediterranean diet and risk of sarcopenia in chinese community older people. Innov Aging 1:1132. https://doi.org/10.1093/geroni/igx004.4138
Shahar DR, Houston DK, Hue TF, Lee J-S, Sahyoun NR, Tylavsky FA et al (2012) Adherence to Mediterranean diet and decline in walking speed over 8 years in community-dwelling older adults. J Am Geriatr Soc 60(10):1881–1888. https://doi.org/10.1111/j.1532-5415.2012.04167.x
Smith A (2014) Sarcopenia, malnutrition and nutrient density in older people. Post Reproduct Health 20(1):19–21. https://doi.org/10.1177/1754045314521552
Rizzoli R, Boonen S, Brandi ML, Bruyere O, Cooper C, Kanis JA et al (2013) Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Curr Med Res Opin 29(4):305–313. https://doi.org/10.1185/03007995.2013.766162
Cianferotti L, Cricelli C, Kanis JA, Nuti R, Reginster JY, Ringe JD et al (2015) The clinical use of vitamin D metabolites and their potential developments: a position statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF). Endocrine 50(1):12–26. https://doi.org/10.1007/s12020-015-0606-x
Veronese N, Maggi S, Noale M, De Rui M, Bolzetta F, Zambon S et al (2015) Serum 25-hydroxyvitamin D and osteoarthritis in older people: the progetto veneto anziani study. Rejuvenation Res. https://doi.org/10.1089/rej.2015.1671
Sanders KM, Scott D, Ebeling PR (2014) Vitamin D deficiency and its role in muscle-bone interactions in the elderly. Curr Osteoporos Rep 12(1):74–81. https://doi.org/10.1007/s11914-014-0193-4
Arik G, Ulger Z (2016) Vitamin D in sarcopenia: understanding its role in pathogenesis, prevention and treatment. Eur Geriatr Med 7(3):207–213. https://doi.org/10.1016/j.eurger.2015.12.001
Bauer JM, Verlaan S, Bautmans I, Brandt K, Donini LM, Maggio M et al (2015) Effects of a vitamin D and leucine-enriched whey protein nutritional supplement on measures of sarcopenia in older adults, the PROVIDE study: a randomized, double-blind, placebo-controlled trial. J Am Med Dir Assoc 16(9):740–747. https://doi.org/10.1016/j.jamda.2015.05.021
Bergink AP, Zillikens MC, Van Leeuwen JP, Hofman A, Uitterlinden AG, van Meurs JB (2016) 25-Hydroxyvitamin D and osteoarthritis: a meta-analysis including new data. Semin Arthr Rheum 45(5):539–546. https://doi.org/10.1016/j.semarthrit.2015.09.010
McAlindon T, LaValley M, Schneider E et al (2013) Effect of vitamin d supplementation on progression of knee pain and cartilage volume loss in patients with symptomatic osteoarthritis: a randomized controlled trial. JAMA 309(2):155–162. https://doi.org/10.1001/jama.2012.164487
Veronese N, Bolzetta F, De Rui M, Zambon S, Corti MC, Musacchio E et al (2014) Serum 25-hydroxyvitamin D and orthostatic hypotension in old people: the Pro.V.A. study. Hypertension 64(3):481–486. https://doi.org/10.1161/hypertensionaha.114.03143
Veronese N, De Rui M, Bolzetta F, Toffanello ED, Coin A, Zambon S et al (2015) Serum 25-hydroxyvitamin D and the incidence of peripheral artery disease in the elderly: the Pro.V.A study. J Atheroscler Thromb 22(7):726–734. https://doi.org/10.5551/jat.28134
Veronese N, Trevisan C, Bolzetta F, De Rui M, Zambon S, Musacchio E et al (2016) Hypovitaminosis D predicts the onset of orthostatic hypotension in older adults. J Am Soc Hypertens. https://doi.org/10.1016/j.jash.2016.06.038
Veronese N, Trevisan C, Carraro S, Sarti S, Zanforlini BM, De Rui M et al (2016) Hypovitaminosis D and fat mass in healthy older people. Eur J Clin Nutr. https://doi.org/10.1038/ejcn.2016.95
