Article (Scientific journals)
Comparison of the effect of trisodium phosphonoformate on the mean plaque size of pseudorabies virus, infectious bovine rhinotracheitis virus and pigeon herpesvirus
Schwers, Anne; Pastoret, Paul-Pierre; Vindevogel, Henri et al.
1980In Journal of Comparative Pathology, 90 (4), p. 625-633
Peer Reviewed verified by ORBi
 

Files


Full Text
Trisodium phosphonoformate pigeon herpes.PDF
Publisher postprint (3.2 MB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Animals; Cattle; Columbidae; Foscarnet; Herpesviridae; Herpesvirus 1, Suid; Organophosphorus Compounds; Phosphonoacetic Acid; Plaque Assay; Rhinovirus; Swine; Animalia; Bovinae; Bovine herpesvirus 1; Bovine rhinotracheitis virus; Columba; Suid herpesvirus 1
Abstract :
[en] The effect of various concentrations of trisodium phosphonoformate on the titre and the mean plaque of pseudorabies virus (SHS), infectious bovine rhinotracheitis (IBR) virus and pigeon herpesvirus (PHV) was studied. Phosphonoformate significantly reduced the mean plaque size of all three viruses whatever the concentration used. However, an increase of the concentration of phosphonoformate over 100 µM per ml in the overlay medium did not further reduce the mean plaque size of PHV. Phosphonoformate also produced a decrease in the titre of the three viruses at the highest concentration. SHV was the most susceptible to the effect of trisodium Phosphonoformate and PHV was the least susceptible. This finding might be of signifiance for a possible clinical application in the treatment of local lesions produced by PHV infection.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Schwers, Anne;  Faculté de médecine vétérinaire, Université de Liège, B-1070 Brussels, Belgium
Pastoret, Paul-Pierre ;  Université de Liège - ULiège > Faculté de médecine vétérinaire
Vindevogel, Henri ;  Université de Liège - ULiège > Faculté de médecine vétérinaire
Leroy, Pascal ;  Université de Liège - ULiège > Faculté de médecine vétérinaire
Aguilar-Setien, A.;  Université de Liège - ULiège > Faculté de médecine vétérinaire
Godart, M.;  Université de Liège - ULiège > Faculté de médecine vétérinaire
Language :
English
Title :
Comparison of the effect of trisodium phosphonoformate on the mean plaque size of pseudorabies virus, infectious bovine rhinotracheitis virus and pigeon herpesvirus
Publication date :
1980
Journal title :
Journal of Comparative Pathology
ISSN :
0021-9975
Publisher :
Academic Press, Liverpool, United Kingdom
Volume :
90
Issue :
4
Pages :
625-633
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 03 May 2019

Statistics


Number of views
34 (4 by ULiège)
Number of downloads
112 (1 by ULiège)

Scopus citations®
 
12
Scopus citations®
without self-citations
7
OpenCitations
 
12

Bibliography


Similar publications



Contact ORBi