[en] Seasonal timing of reproduction is a key life-history trait, but we know little about the mechanisms underlying individual variation in female endocrine profiles associated with reproduction. In birds, 17b-oestradiol is a key repro- ductive hormone that links brain neuroendocrine mechanisms, involved in information processing and decision-making, to downstream mechanisms in the liver, where egg-yolk is produced. Here, we test, using a simulated induction of the reproductive system through a GnRH challenge, whether the ovary of pre-breeding female great tits responds to a brain stimulation by increasing oestradiol. We also assess how this response is modified by individual-specific traits like age, ovarian follicle size and personality, using females from lines artificially selected for divergent levels of explora- tory behaviour. We show that a GnRH injection leads to a rapid increase in circulating concentrations of oestradiol, but responses varied among individ- uals. Females with more developed ovarian follicles showed stronger responses and females from lines selected for fast exploratory behaviour showed stronger increases compared to females from the slow line, indicat- ing a heritable component. This study shows that the response of the ovary to a reproductive stimulation from the brain greatly varies among individ- uals and that this variation can be attributed to several commonly measured individual traits, which sheds light on the mechanisms shaping heritable endocrine phenotypes.
Research Center/Unit :
Giga-Neurosciences - ULiège
Disciplines :
Neurosciences & behavior
Author, co-author :
Caro, Samuel
Cornil, Charlotte ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biologie de la différenciation sexuelle du cerveau
van Oers, Kees
Visser, Marcel
Language :
English
Title :
Personality and gonadal development as sources of individual variation in response to GnRH challenge in female great tits
Publication date :
2019
Journal title :
Proceedings of the Royal Society of London. Series B, Biological Sciences
ISSN :
0080-4649
Publisher :
Royal Society
Volume :
286
Issue :
1902
Pages :
20190142
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
CNRS - Centre National de la Recherche Scientifique F.R.S.-FNRS - Fonds de la Recherche Scientifique
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