[en] This study shows that, during collagen-initiated platelet activation, the early secretion of ATP results in the activation of the P2X1 ion channel, which plays a role as a positive regulator of further platelet responses.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Oury, Cécile ; Katholieke Universiteit Leuven - KUL > Molecular and Cellular Medicine > CMVB
Toth-Zsamboki, Emese; Katholieke Universiteit Leuven - KUL > Molecular and Cellular Medicine > CMVB
Thijs, Chantal; Katholieke Universiteit Leuven - KUL > Molecular and Cellular Medicine > CMVB
Vermylen, Jos; Katholieke Universiteit Leuven - KUL > Molecular and Cellular Medicine > CMVB
Hoylaerts, Marc F; Katholieke Universiteit Leuven - KUL > Molecular and Cellular Medicine > CMVB
Language :
English
Title :
The ATP-gated P2X1 ion channel acts as a positive regulator of platelet responses to collagen.
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