Article (Scientific journals)
Empirical examination of the replicability of associations between brain structure and psychological variables
Kharabian Masouleh, Shahrzad; Eickhoff, Simon; Hoffstaedter, Felix et al.
2019In eLife, 13 (8), p. 43464
Peer Reviewed verified by ORBi
 

Files


Full Text
Kharabian_et_al_replicabilitySBB_preprint.pdf
Author preprint (29.13 MB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Abstract :
[en] Linking interindividual differences in psychological phenotype to variations in brain structure is an old dream for psychology and a crucial question for cognitive neurosciences. Yet, replicability of the previously-reported “structural brain behavior” (SBB)-associations has been questioned, recently. Here, we conducted an empirical investigation, assessing replicability of SBB among heathy adults. For a wide range of psychological measures, the replicability of associations with gray matter volume was assessed. Our results revealed that among healthy individuals 1) finding an association between performance at standard psychological tests and brain morphology is relatively unlikely 2) significant associations, found using an exploratory approach, have overestimated effect sizes and 3) can hardly be replicated in an independent sample. After considering factors such as sample size and comparing our findings with more replicable SBB-associations in a clinical cohort and replicable associations between brain structure and non-psychological phenotype, we discuss the potential causes and consequences of these findings.
Disciplines :
Neurosciences & behavior
Author, co-author :
Kharabian Masouleh, Shahrzad
Eickhoff, Simon
Hoffstaedter, Felix
Genon, Sarah ;  Université de Liège - ULiège > Département des sciences cliniques > Neuroimagerie des troubles de la mémoire et revalid. cogn.
Language :
English
Title :
Empirical examination of the replicability of associations between brain structure and psychological variables
Publication date :
March 2019
Journal title :
eLife
eISSN :
2050-084X
Publisher :
eLife Sciences Publications, United Kingdom
Volume :
13
Issue :
8
Pages :
e43464
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 28 March 2019

Statistics


Number of views
92 (7 by ULiège)
Number of downloads
238 (3 by ULiège)

Scopus citations®
 
104
Scopus citations®
without self-citations
89
OpenCitations
 
67

Bibliography


Similar publications



Contact ORBi