Reference : Localization of interleukin 6 mRNA in human tonsils by in situ hybridization.
Scientific journals : Article
Life sciences : Anatomy (cytology, histology, embryology...) & physiology
http://hdl.handle.net/2268/23268
Localization of interleukin 6 mRNA in human tonsils by in situ hybridization.
English
Bosseloir, A. [> > > >]
Hooghe-Peters, E. L. [> > > >]
Heinen, Ernst mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Histologie humaine >]
Cormann, N. [> > > >]
Kinet-Denoel, C. [> > > >]
Vanhaelst, L. [> > > >]
Simar, L. [> > > >]
1989
European Journal of Immunology
VCH Verlagsgesellschaft
19
12
2379-81
Yes (verified by ORBi)
International
0014-2980
1521-4141
Weinheim
Germany
[en] B-Lymphocytes/physiology ; DNA Probes ; Humans ; Interleukin-6/genetics ; Nucleic Acid Hybridization ; Palatine Tonsil/cytology/physiology ; RNA, Messenger/genetics
[en] We have investigated which areas produce interleukin 6 (IL 6) in human tonsils. This growth factor is required for the terminal differentiation of B lymphocytes into plasmocytes. Using 35S-labeled IL 6 cDNA we demonstrated IL 6 gene expression over various areas of the tonsils, with consistent exception of the follicles, by in situ hybridization. It is, therefore, proposed that B cells are stimulated during their migration out of the follicles.
http://hdl.handle.net/2268/23268
also: http://hdl.handle.net/2268/23272
10.1002/eji.1830191230

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