[en] Singlet oxygen ((1) O2 ) signalling in plants is essential to trigger both acclimatory mechanisms and programmed cell death under high light stress. However, because of its chemical features, (1) O2 requires mediators, and the players involved in this pathway are largely unknown. The beta-carotene oxidation product, beta-cyclocitral, is one such mediator. Produced in the chloroplast, beta-cyclocitral induces changes in nuclear gene expression leading to photoacclimation. Recently, the METHYLENE BLUE SENSITIVITY protein MBS has been identified as a key player in (1) O2 signalling leading to tolerance to high light. Here, we provide evidence that MBS1 is essential for acclimation to (1) O2 and cross-talks with beta-cyclocitral to mediate transfer of the (1) O2 signal to the nucleus, leading to photoacclimation. The presented results position MBS1 downstream of beta-cyclocitral in (1) O2 signalling and suggest an additional role for MBS1 in the regulation of plant growth and development under chronic (1) O2 production.
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