Article (Scientific journals)
Human consciousness is supported by dynamic complex patterns of brain signal coordination
Demertzi, Athina; Tagliazucchi, Enzo; Dehaene, S et al.
2019In Science Advances, 5 (2), p. 7603
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Abstract :
[en] Adopting the framework of brain dynamics as a cornerstone of human consciousness, we determined whether dynamic signal coordination provides specific and generalizable patterns pertaining to conscious and unconscious states after brain damage. A dynamic pattern of coordinated and anticoordinated functional magnetic resonance imaging signals characterized healthy individuals and minimally conscious patients. The brains of unresponsive patients showed primarily a pattern of low interareal phase coherence mainly mediated by structural connectivity, and had smaller chances to transition between patterns. The complex pattern was further corroborated in patients with covert cognition, who could perform neuroimaging mental imagery tasks, validating this pattern’s implication in consciousness. Anesthesia increased the probability of the less complex pattern to equal levels, validating its implication in unconsciousness. Our results establish that consciousness rests on the brain’s ability to sustain rich brain dynamics and pave the way for determining specific and generalizable fingerprints of conscious and unconscious states.
Disciplines :
Neurosciences & behavior
Author, co-author :
Demertzi, Athina   ;  Université de Liège - ULiège > GIGA : Coma Group
Tagliazucchi, Enzo 
Dehaene, S
Deco, G
Barttfeld, P
Raimondo, Federico ;  Université de Liège - ULiège > GIGA-Research
Martial, Charlotte  ;  Université de Liège - ULiège > GIGA : Coma Group
Fernandez-Espejo, D
Rohaut, B
Voss, HU
Schiff, ND
Owen, AM
Laureys, Steven  ;  Université de Liège - ULiège > GIGA : Coma Group
Naccache, Lionel
Sitt, JD
More authors (5 more) Less
 These authors have contributed equally to this work.
Language :
English
Title :
Human consciousness is supported by dynamic complex patterns of brain signal coordination
Publication date :
February 2019
Journal title :
Science Advances
eISSN :
2375-2548
Publisher :
American Association for the Advancement of Science (AAAS), Washington, United States - District of Columbia
Volume :
5
Issue :
2
Pages :
eaat7603
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 19 November 2018

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