Positron emission tomography in non-Hodgkin's lymphoma (NHL): relationship between tracer uptake and pathological findings, including preliminary experience in the staging of low-grade NHL.

Jerusalem, Guy; Beguin, Yves

doi:10.3816/CLM.2002.n.012

Article (Scientific journals)

Positron emission tomography in non-Hodgkin's lymphoma (NHL): relationship between tracer uptake and pathological findings, including preliminary experience in the staging of low-grade NHL.

Jerusalem, Guy; Beguin, Yves

2002 • In Clinical Lymphoma, 3 (1), p. 56-61

Peer Reviewed verified by ORBi

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https://hdl.handle.net/2268/22926

DOI
10.3816/CLM.2002.n.012

PubMed
12141957

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Keywords :

Carbon Radioisotopes/diagnostic use/pharmacokinetics; Cell Division; Disease Progression; Fluorodeoxyglucose F18/diagnostic use/pharmacokinetics; Humans; Lymph Nodes/radionuclide imaging; Lymphoma, Non-Hodgkin/diagnosis/metabolism/pathology/radionuclide imaging; Methionine/diagnostic use/pharmacokinetics; Neoplasm Staging/methods; Prognosis; Radiopharmaceuticals/diagnostic use/pharmacokinetics; Sensitivity and Specificity; Tissue Distribution; Tomography, Emission-Computed

Abstract :

[en] Advances in imaging techniques have allowed more precise staging and better evaluation of the effect of new treatment modalities. The limitations of conventional morphologic imaging techniques are well known. Positron emission tomography (PET) using fluorine-18-labeled fluorodeoxyglucose is now routinely used for initial staging and re-evaluation during or after treatment of Hodgkin's disease and aggressive non-Hodgkin's lymphoma (NHL), but not in low-grade NHL. In the first part of this review, the relationship between glucose metabolism as measured by PET, pathological findings including histological grade and proliferative activity, and prognosis are analyzed. In the second part, the potential role of PET in the staging and follow-up of low-grade NHL is discussed. Published data indicate that PET may contribute to the management of low-grade follicular NHL.

Disciplines :

Hematology

Author, co-author :

Jerusalem, Guy ; Centre Hospitalier Universitaire de Liège - CHU > Oncologie médicale

Beguin, Yves ; Centre Hospitalier Universitaire de Liège - CHU > Hématologie clinique

Language :

English

Title :

Positron emission tomography in non-Hodgkin's lymphoma (NHL): relationship between tracer uptake and pathological findings, including preliminary experience in the staging of low-grade NHL.

Publication date :

2002

Journal title :

Clinical Lymphoma

ISSN :

1526-9655

Publisher :

Cancer Information Group, Dallas, United States - Texas

Volume :

Issue :

Pages :

56-61

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 18 September 2009

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