2018 • In EuroIntervention: Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 13 (13), p. 1603-1611
[en] AIMS: This study aimed to assess the safety and efficacy at midterm follow-up of left atrial appendage occlusion (LAAO) using different devices, in real life in Belgium. METHODS AND RESULTS: Between June 2009 and November 2016, 457 consecutive patients (63% male, 75+/-12 yrs, CHA2DS2-VASc 4+/-0.6, HAS-BLED 3.5+/-0.7) undergoing LAAO were included. Technical success was 97.1%. There were 19 periprocedural major adverse events (4.1%) including three deaths (0.6%), nine tamponades (1.9%), four major bleedings (0.8%) and two device embolisations (0.4%). Among patients successfully implanted having a complete follow-up (672 patient-years, median follow-up 370 days), the actual annual stroke rate was 1.2%, lower than the expected stroke risk of 4% (70% reduction). The observed bleeding rate was 2%, while the calculated risk was 3.7% (46% reduction). Kaplan-Meier analysis showed a similar overall survival (93+/-2% and 87+/-3% versus 91+/-3% and 87+/-4%; p=0.35) and event-free survival (92+/-2% and 84+/-3% versus 88+/-3% and 80+/-5%; p=0.17) at one and two years, for the ACP/Amulet versus the WATCHMAN groups of patients, respectively. CONCLUSIONS: The data from the Belgian left atrial appendage occlusion registry suggest that the procedure is effective and relatively safe in a real-world setting, using either the WATCHMAN or the ACP/Amulet device.
Disciplines :
Cardiovascular & respiratory systems
Author, co-author :
Kefer, Joelle
Aminian, Adel
Vermeersch, Paul
de Potter, Tom
Stammen, Francis
Benit, Edouard
Budts, Werner
Missault, Luc
Drieghe, Benny
Buysschaert, Ian
Cornelis, Kristoff
Herzet, Jean-Manuel
Guedes, Antoine
Debbas, Nadia
Rivero, Maximo
LEMPEREUR, Mathieu ; Centre Hospitalier Universitaire de Liège - CHU > Département de médecine interne > Cardiologie interventionnelle
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