Reference : De l'atherosclerose a l'atherothrombose: D'une pathologie chronique silencieuse a un ...
Scientific journals : Article
Human health sciences : Cardiovascular & respiratory systems
http://hdl.handle.net/2268/227135
De l'atherosclerose a l'atherothrombose: D'une pathologie chronique silencieuse a un accident aigu critique.
French
[en] From atherosclerosis to atherothrombosis : from a silent chronic pathology to an acute critical event
Scheen, André mailto [Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques >]
2018
Revue medicale de Liege
73
5-6
224-228
Yes (verified by ORBi)
National
0370-629X
Belgium
[en] Atherosclerosis ; MACE ; Myocardial infarction - Stroke - Type 2 diabetes - Thrombosis ; Myocardial infarction ; Stroke ; Type 2 diabetes ; Thrombosis
[en] Cardiovascular disease still represents, together with cancer, a major cause of morbidity and mortality. Atherosclerosis is a silent progressive process, which can start in early life and usually progresses with advancing age. Besides genetic predisposition, atherosclerosis is accelerated by the presence of several modifiable risk factors such as smoking, dyslipidaemia, arterial hypertension and diabetes mellitus. Asymptomatic atherosclerosis may lead to an acute event, mostly due to plaque rupture and secondary thrombosis. If the thrombus is occlusive, according to the artery where it occurs, the acute complication involves most often an acute coronary event or an ischaemic stroke. Major cardiovascular events (MACEs) represent the primary outcome in a majority of clinical trials. Some populations, as patients with type 2 diabetes, are especially prone to these complications due to atherothrombosis linked to subclinical accelerated atherosclerosis. In most cases, an emergency intervention is mandatory to avoid premature death or irreversible sequelae.
Researchers ; Professionals ; Students
http://hdl.handle.net/2268/227135
https://www.rmlg.ulg.ac.be

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