[en] Poly(vinylamine) is a highly valuable class of polymer used in several applications. Although free radical polymerization has been extensively exploited for its synthesis, the preparation of poly(vinylamine) with low dispersity and controlled molar mass is barely developed. Recently, a great step was made in this direction via organometallic-mediated radical polymerization (OMRP) of N-vinylacetamides followed by hydrolysis of the pendent amide groups. This chapter summarizes, completes and put in perspective the main accomplishments in the OMRP of acyclic N-vinylamides for the controlled synthesis of both primary and secondary poly(vinylamine)s. Thermal and photochemical initiating systems are compared and the controlled thermally initiated radical polymerization of N-vinylacetamide is reported for the first time. The optimal hydrolysis conditions for producing the poly(vinylamine) derivatives as well as their potential as vectors for gene transfection are also presented.
Research Center/Unit :
CESAM - Complex and Entangled Systems from Atoms to Materials - ULiège Center for Education and Research on Macromolecules (CERM)
Disciplines :
Chemistry Materials science & engineering
Author, co-author :
Stiernet, Pierre ; University of Liège (ULiège), Complex and Entangled Systems from Atoms to Materials (CESAM), Center for Education and Research on Macromolecules (CERM)
Dréan, Mathilde; University of Liège (ULiège), Complex and Entangled Systems from Atoms to Materials (CESAM), Center for Education and Research on Macromolecules (CERM)
Jérôme, Christine ; University of Liège (ULiège), Complex and Entangled Systems from Atoms to Materials (CESAM), Center for Education and Research on Macromolecules (CERM)
Midoux, Patrick; Centre Biophysique Moléculaire, CNRS, Orléans, France
Guégan, Patrick; Sorbonne University, Institut Parisien de Chimie Moléculaire (IPCM), Paris, France
Rieger, Jutta; Sorbonne University, Institut Parisien de Chimie Moléculaire (IPCM), Paris, France
Debuigne, Antoine ; University of Liège (ULiège), Complex and Entangled Systems from Atoms to Materials (CESAM), Center for Education and Research on Macromolecules (CERM)
Language :
English
Title :
Tailor-made poly(vinylamine)s via thermal or photochemical organometallic mediated radical polymerization
Publication date :
2018
Main work title :
ACS Symposium Series
Editor :
Matyjaszewski, Krzysztof
Gao, Haifeng
Sumerlin, Brent S.
Tsarevsky, Nicolay V.
Publisher :
American Chemical Society, United States
Pages :
349-363
Peer reviewed :
Peer reviewed
Funders :
BELSPO - SPP Politique scientifique - Service Public Fédéral de Programmation Politique scientifique F.R.S.-FNRS - Fonds de la Recherche Scientifique The European Community in the frame of the International Doctoral School IDS-Funmat
