How to Characterize the Function of a Brain Region

[en] Many brain regions have been defined, but a comprehensive formalization of each region's function in relation to human behavior is still lacking. Current knowledge comes from various fields, which have diverse conceptions of 'functions'. We briefly review these fields and outline how the heterogeneity of associations could be harnessed to disclose the computational function of any region. Aggregating activation data from neuroimaging studies allows us to characterize the functional engagement of a region across a range of experimental conditions. Furthermore, large-sample data can disclose covariation between brain region features and ecological behavioral phenotyping. Combining these two approaches opens a new perspective to determine the behavioral associations of a brain region, and hence its function and broader role within large-scale functional networks.

Disciplines :

Neurosciences & behavior

Author, co-author :

Genon, Sarah ; Université de Liège - ULiège > Département des sciences cliniques > Neuroimagerie des troubles de la mémoire et révalid. cogn.

Reid, Andrew

Langner, Robert

Amunts, Katrin

Eickhoff, Simon

Language :

English

Title :

How to Characterize the Function of a Brain Region

Publication date :

April 2018

Journal title :

Trends in Cognitive Sciences

ISSN :

1364-6613

eISSN :

1879-307X

Publisher :

Elsevier, Netherlands

Volume :

Issue :

Pages :

350-364

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 25 June 2018

Statistics

Number of views

158 (3 by ULiège)

Number of downloads

169 (2 by ULiège)

More statistics

Scopus citations^®

152

Scopus citations^®
without self-citations

124

OpenCitations

121

OpenAlex citations

200

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