Reference : Can Blood Biomarkers Help Predicting Outcome in Transcatheter Aortic Valve Implantation?
Scientific journals : Article
Human health sciences : Cardiovascular & respiratory systems
http://hdl.handle.net/2268/225750
Can Blood Biomarkers Help Predicting Outcome in Transcatheter Aortic Valve Implantation?
English
Oury, Cécile mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > GIGA-R : GIGA - Cardiovascular Sciences >]
Nchimi Longang, Alain [Université de Liège - ULiège > Département des sciences cliniques > Cardiologie - Pathologie spéciale et réhabilitation >]
Lancellotti, Patrizio [Université de Liège - ULiège > Département des sciences cliniques > Cardiologie - Pathologie spéciale et réhabilitation >]
Bergler-Klein, Jutta [> >]
2018
Frontiers in cardiovascular medicine
5
31
Yes
International
2297-055X
Switzerland
[en] TAVI ; blood biomarkers ; inflammation ; myocardial stress ; platelet ; thrombocytopenia
[en] Transcatheter aortic valve implantation (TAVI) has become the method of choice for patients with severe aortic valve stenosis, who are ineligible or at high risk for surgery. In this high risk patient population, early and late mortality and rehospitalization rates after TAVI are still relatively high. In spite of recent improvements in procedural TAVI, and establishment of risk models for poor outcome, determining individual risk remains challenging. In this context, current data from several small studies strongly suggest that blood biomarkers of myocardial injury, cardiac mechanical stretch, inflammation, and hemostasis imbalance might play an important role by providing informations on patient risk at baseline, and postprocedural progression of patient clinical conditions from days up to years post-TAVI. Although the role of biomarkers for predicting survival post-TAVI remains to be validated in large randomized studies, implementing biomarkers in clinical practice might improve risk stratification, thereby further reducing TAVI-associated morbidity and mortality.
http://hdl.handle.net/2268/225750
10.3389/fcvm.2018.00031

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Open access
fcvm-05-00031.pdfPublisher postprint358.83 kBView/Open

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.