Article (Scientific journals)
The Iowa Gambling Task in fMRI images.
Li, Xiang; Lu, Zhong-Lin; D'Argembeau, Arnaud et al.
2010In Human Brain Mapping, 31, p. 410-423
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Abstract :
[en] The Iowa Gambling Task (IGT) is a sensitive test for the detection of decision-making impairments in several neurological and psychiatric populations. Very few studies have employed the IGT in functional magnetic resonance imaging (fMRI) investigations, in part, because the task is cognitively complex. Here we report a method for exploring brain activity using fMRI during performance of the IGT. Decision-making during the IGT was associated with activity in several brain regions in a group of healthy individuals. The activated regions were consistent with the neural circuitry hypothesized to underlie somatic marker activation and decision-making. Specifically, a neural circuitry involving the dorsolateral prefrontal cortex (for working memory), the insula and posterior cingulate cortex (for representations of emotional states), the mesial orbitofrontal and ventromedial prefrontal cortex (for coupling the two previous processes), the ventral striatum and anterior cingulate/SMA (supplementary motor area) for implementing behavioral decisions was engaged. These results have implications for using the IGT to study abnormal mechanisms of decision making in a variety of clinical populations. Hum Brain Mapp, 2009. (c) 2009 Wiley-Liss, Inc.
Disciplines :
Neurosciences & behavior
Author, co-author :
Li, Xiang ;  Université de Liège - ULiège > Département Argenco : Secteur MS2F > Mécanique des solides
Lu, Zhong-Lin
D'Argembeau, Arnaud  ;  Université de Liège - ULiège > Département des sciences cognitives > Psychopathologie cognitive
Ng, Marie
Bechara, Antoine
Language :
English
Title :
The Iowa Gambling Task in fMRI images.
Publication date :
2010
Journal title :
Human Brain Mapping
ISSN :
1065-9471
eISSN :
1097-0193
Publisher :
Wiley Liss, Inc., New York, United States - New York
Volume :
31
Pages :
410-423
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 10 May 2010

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