The Iowa Gambling Task in fMRI images.

[en] The Iowa Gambling Task (IGT) is a sensitive test for the detection of decision-making impairments in several neurological and psychiatric populations. Very few studies have employed the IGT in functional magnetic resonance imaging (fMRI) investigations, in part, because the task is cognitively complex. Here we report a method for exploring brain activity using fMRI during performance of the IGT. Decision-making during the IGT was associated with activity in several brain regions in a group of healthy individuals. The activated regions were consistent with the neural circuitry hypothesized to underlie somatic marker activation and decision-making. Specifically, a neural circuitry involving the dorsolateral prefrontal cortex (for working memory), the insula and posterior cingulate cortex (for representations of emotional states), the mesial orbitofrontal and ventromedial prefrontal cortex (for coupling the two previous processes), the ventral striatum and anterior cingulate/SMA (supplementary motor area) for implementing behavioral decisions was engaged. These results have implications for using the IGT to study abnormal mechanisms of decision making in a variety of clinical populations. Hum Brain Mapp, 2009. (c) 2009 Wiley-Liss, Inc.

Disciplines :

Neurosciences & behavior

Author, co-author :

Li, Xiang ; Université de Liège - ULiège > Département Argenco : Secteur MS2F > Mécanique des solides

Lu, Zhong-Lin

D'Argembeau, Arnaud ; Université de Liège - ULiège > Département des sciences cognitives > Psychopathologie cognitive

Ng, Marie

Bechara, Antoine

Language :

English

Title :

The Iowa Gambling Task in fMRI images.

Publication date :

2010

Journal title :

Human Brain Mapping

ISSN :

1065-9471

eISSN :

1097-0193

Publisher :

Wiley Liss, Inc., New York, United States - New York

Volume :

Pages :

410-423

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 10 May 2010

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